Details for: Hsd17b3

Gene ID: 15487

Symbol: Hsd17b3

Ensembl ID: ENSMUSG00000033122

Description: hydroxysteroid (17-beta) dehydrogenase 3

Associated with

Other Information

Genular Protein ID: 4288344616

Symbol: DHB3_MOUSE

Name: 17-beta-hydroxysteroid dehydrogenase type 3

UniProtKB Accession Codes:

P70385 G3UWF9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChEBI 46 ChEMBL 1 ChiTaRS 1 DNASU 1 EC 2 EMBL 3 Ensembl 3 ExpressionAtlas 1 GO 7 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 3 KEGG 1 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRINTS 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 1 Rhea 18 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 9182854

Title: Sequence of mouse 17beta-hydroxysteroid dehydrogenase type 3 cDNA and tissue distribution of the type 1 and type 3 isoform mRNAs.

PubMed ID: 9182854

DOI: 10.1016/s0960-0760(96)00165-3

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 32190925

Title: The lack of HSD17B3 in male mice results in disturbed Leydig cell maturation and endocrine imbalance akin to humans with HSD17B3 deficiency.

PubMed ID: 32190925

DOI: 10.1096/fj.201902384r

PubMed ID: 32557858

Title: Ablation of the canonical testosterone production pathway via knockout of the steroidogenic enzyme HSD17B3, reveals a novel mechanism of testicular testosterone production.

PubMed ID: 32557858

DOI: 10.1096/fj.202000361r

Sequence Information:

  • Length: 305
  • Mass: 34330
  • Checksum: 8EA9966B2777064D
  • Sequence:
    • MEKLFIAAGL FVGLVCLVKC MRFSQHLFLR FCKALPSSFL RSMGQWAVIT GAGDGIGKAY 
SFELARHGLN VVLISRTLEK LQTIAEEIER TTGSCVKIVQ ADFTREDIYD HIKEHLEGLE 
IGILVNNVGM LPSFFPSHFL STSGESQNLI HCNITSVVKM TQLVLKHMES RRKGLILNIS 
SGAALRPWPL YSLYSASKAF VYTFSKALSV EYRDKGIIIQ VLTPYSISTP MTKYLNNKMT 
KTADEFVKES LKYVTIGAES CGCLAHEIIA IILNRIPSRI FYSSTAQRFL LTRYSDYLKR 
NISNR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.