Genular: Defining Cellular Identity and Function

Details for: Hsd17b4

Gene ID: 15488

Symbol: Hsd17b4

Ensembl ID: ENSMUSG00000024507

Description: hydroxysteroid (17-beta) dehydrogenase 4

Associated with

Alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
(R-MMU-2046104)
Alpha-linolenic acid (ala) metabolism
(R-MMU-2046106)
Beta-oxidation of pristanoyl-coa
(R-MMU-389887)
Beta-oxidation of very long chain fatty acids
(R-MMU-390247)
Bile acid and bile salt metabolism
(R-MMU-194068)
Fatty acid metabolism
(R-MMU-8978868)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Metabolism of steroids
(R-MMU-8957322)
Peroxisomal lipid metabolism
(R-MMU-390918)
Peroxisomal protein import
(R-MMU-9033241)
Protein localization
(R-MMU-9609507)
Synthesis of bile acids and bile salts
(R-MMU-192105)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
(R-MMU-193368)
(3r)-hydroxyacyl-coa dehydrogenase (nad) activity
(GO:0106386)
3-hydroxyacyl-coa dehydratase activity
(GO:0018812)
3-hydroxyacyl-coa dehydrogenase activity
(GO:0003857)
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-coa hydratase activity
(GO:0033989)
17-beta-hydroxysteroid dehydrogenase (nad+) activity
(GO:0044594)
Androgen metabolic process
(GO:0008209)
Enoyl-coa hydratase activity
(GO:0004300)
Estradiol 17-beta-dehydrogenase [nad(p)] activity
(GO:0004303)
Estrogen metabolic process
(GO:0008210)
Fatty acid beta-oxidation
(GO:0006635)
Fatty acid metabolic process
(GO:0006631)
Identical protein binding
(GO:0042802)
Isomerase activity
(GO:0016853)
Lipid metabolic process
(GO:0006629)
Lyase activity
(GO:0016829)
Medium-chain fatty-acyl-coa metabolic process
(GO:0036112)
Mitochondrion
(GO:0005739)
Oxidoreductase activity
(GO:0016491)
Peroxisomal matrix
(GO:0005782)
Peroxisome
(GO:0005777)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Sertoli cell development
(GO:0060009)
Very long-chain fatty-acyl-coa metabolic process
(GO:0036111)
Very long-chain fatty acid metabolic process
(GO:0000038)

Other Information

Proteins

17-beta-hydroxysteroid dehydrogenase 4

Genular Protein ID: 1935981992

Symbol: DHB4_MOUSE

Name: 17-beta-hydroxysteroid dehydrogenase 4

UniProtKB Accession Codes:

P51660 Q9DBM3

Database IDs:

Citations:

PubMed ID: 8547180

Title: Molecular characterization of mouse 17 beta-hydroxysteroid dehydrogenase IV.

PubMed ID: 8547180

DOI: 10.1016/0960-0760(95)00204-9

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17442273

Title: Beta-oxidation in hepatocyte cultures from mice with peroxisomal gene knockouts.

PubMed ID: 17442273

DOI: 10.1016/j.bbrc.2007.03.198

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

Sequence Information:

Length: 735
Mass: 79482
Checksum: AD7804FE93EB9BA8
Sequence:

MASPLRFDGR VVLVTGAGGG LGRAYALAFA ERGALVIVND LGGDFKGIGK GSSAADKVVA 
EIRRKGGKAV ANYDSVEAGE KLVKTALDTF GRIDVVVNNA GILRDRSFSR ISDEDWDIIH 
RVHLRGSFQV TRAAWDHMKK QNYGRILMTS SASGIYGNFG QANYSAAKLG ILGLCNTLAI 
EGRKNNIHCN TIAPNAGSRM TETVLPEDLV EALKPEYVAP LVLWLCHESC EENGGLFEVG 
AGWIGKLRWE RTLGAIVRKR NQPMTPEAVR DNWEKICDFS NASKPQTIQE STGGIVEVLH 
KVDSEGISPN RTSHAAPAAT SGFVGAVGHK LPSFSSSYTE LQSIMYALGV GASVKNPKDL 
KFVYEGSADF SCLPTFGVIV AQKSMMNGGL AEVPGLSFNF AKALHGEQYL ELYKPLPRSG 
ELKCEAVIAD ILDKGSGVVI VMDVYSYSGK ELICYNQFSV FVVGSGGFGG KRTSEKLKAA 
VAVPNRPPDA VLRDATSLNQ AALYRLSGDW NPLHIDPDFA SVAGFEKPIL HGLCTFGFSA 
RHVLQQFADN DVSRFKAIKV RFAKPVYPGQ TLQTEMWKEG NRIHFQTKVH ETGDVVISNA 
YVDLVPASGV STQTPSEGGE LQSALVFGEI GRRLKSVGRE VVKKANAVFE WHITKGGTVA 
AKWTIDLKSG SGEVYQGPAK GSADVTIIIS DEDFMEVVFG KLDPQKAFFS GRLKARGNIM 
LSQKLQMILK DYAKL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hsd17b4

Associated with

Other Information

Molecular characterization of mouse 17 beta-hydroxysteroid dehydrogenase IV. PubMed ID: 8547180

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Beta-oxidation in hepatocyte cultures from mice with peroxisomal gene knockouts. PubMed ID: 17442273

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. PubMed ID: 23576753