Genular: Defining Cellular Identity and Function

Details for: Hspa1b

Gene ID: 15511

Symbol: Hspa1b

Ensembl ID: ENSMUSG00000090877

Description: heat shock protein 1B

Associated with

Antiviral mechanism by ifn-stimulated genes
(R-MMU-1169410)
Attenuation phase
(R-MMU-3371568)
Auf1 (hnrnp d0) binds and destabilizes mrna
(R-MMU-450408)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to heat stress
(R-MMU-3371556)
Cytokine signaling in immune system
(R-MMU-1280215)
Hsf1-dependent transactivation
(R-MMU-3371571)
Hsp90 chaperone cycle for steroid hormone receptors (shr) in the presence of ligand
(R-MMU-3371497)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Interferon signaling
(R-MMU-913531)
Metabolism of rna
(R-MMU-8953854)
Neutrophil degranulation
(R-MMU-6798695)
Pkr-mediated signaling
(R-MMU-9833482)
Regulation of hsf1-mediated heat shock response
(R-MMU-3371453)
Regulation of mrna stability by proteins that bind au-rich elements
(R-MMU-450531)
Aggresome
(GO:0016235)
Apical plasma membrane
(GO:0016324)
Atp-dependent protein disaggregase activity
(GO:0140545)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Basolateral plasma membrane
(GO:0016323)
Binding of sperm to zona pellucida
(GO:0007339)
C3hc4-type ring finger domain binding
(GO:0055131)
Cell body
(GO:0044297)
Centriole
(GO:0005814)
Centrosome
(GO:0005813)
Chaperone cofactor-dependent protein refolding
(GO:0051085)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Enzyme binding
(GO:0019899)
G protein-coupled receptor binding
(GO:0001664)
Heat shock protein binding
(GO:0031072)
Histone deacetylase binding
(GO:0042826)
Inclusion body
(GO:0016234)
Intracellular anatomical structure
(GO:0005622)
Membrane raft
(GO:0045121)
Mitochondrial matrix
(GO:0005759)
Mitochondrion
(GO:0005739)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0043154)
Nf-kappab binding
(GO:0051059)
Nuclear speck
(GO:0016607)
Nucleus
(GO:0005634)
Perinuclear region of cytoplasm
(GO:0048471)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process
(GO:0032436)
Protease binding
(GO:0002020)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein folding
(GO:0006457)
Protein folding chaperone
(GO:0044183)
Protein refolding
(GO:0042026)
Regulation of mitotic spindle assembly
(GO:1901673)
Response to heat
(GO:0009408)
Ribonucleoprotein complex
(GO:1990904)
Signaling receptor binding
(GO:0005102)
Ubiquitin protein ligase binding
(GO:0031625)
Unfolded protein binding
(GO:0051082)
Zona pellucida receptor complex
(GO:0002199)

Other Information

Proteins

Heat shock 70 kDa protein 1B

Genular Protein ID: 1740305354

Symbol: HS71B_MOUSE

Name: Heat shock 70 kDa protein 1B

UniProtKB Accession Codes:

P17879 Q61689 Q925V6

Database IDs:

Citations:

PubMed ID: 2332169

Title: Characterization and sequence of a mouse hsp70 gene and its expression in mouse cell lines.

PubMed ID: 2332169

DOI: 10.1016/0378-1119(90)90302-8

PubMed ID: 14656967

Title: Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.

PubMed ID: 14656967

DOI: 10.1101/gr.1736803

PubMed ID: 17478420

Title: CatSperbeta, a novel transmembrane protein in the CatSper channel complex.

PubMed ID: 17478420

DOI: 10.1074/jbc.m701083200

PubMed ID: 19516020

Title: A novel, single, transmembrane protein CATSPERG is associated with CATSPER1 channel protein.

PubMed ID: 19516020

DOI: 10.1095/biolreprod.109.077107

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23973223

Title: The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3.

PubMed ID: 23973223

DOI: 10.1016/j.immuni.2013.08.006

Sequence Information:

Length: 642
Mass: 70176
Checksum: 4BB9B0B130C23D8B
Sequence:

MAKNTAIGID LGTTYSCVGV FQHGKVEIIA NDQGNRTTPS YVAFTDTERL IGDAAKNQVA 
LNPQNTVFDA KRLIGRKFGD AVVQSDMKHW PFQVVNDGDK PKVQVNYKGE SRSFFPEEIS 
SMVLTKMKEI AEAYLGHPVT NAVITVPAYF NDSQRQATKD AGVIAGLNVL RIINEPTAAA 
IAYGLDRTGK GERNVLIFDL GGGTFDVSIL TIDDGIFEVK ATAGDTHLGG EDFDNRLVSH 
FVEEFKRKHK KDISQNKRAV RRLRTACERA KRTLSSSTQA SLEIDSLFEG IDFYTSITRA 
RFEELCSDLF RGTLEPVEKA LRDAKMDKAQ IHDLVLVGGS TRIPKVQKLL QDFFNGRDLN 
KSINPDEAVA YGAAVQAAIL MGDKSENVQD LLLLDVAPLS LGLETAGGVM TALIKRNSTI 
PTKQTQTFTT YSDNQPGVLI QVYEGERAMT RDNNLLGRFE LSGIPPAPRG VPQIEVTFDI 
DANGILNVTA TDKSTGKANK ITITNDKGRL SKEEIERMVQ EAERYKAEDE VQRDRVAAKN 
ALESYAFNMK SAVEDEGLKG KLSEADKKKV LDKCQEVISW LDSNTLADKE EFVHKREELE 
RVCSPIISGL YQGAGAPGAG GFGAQAPPKG ASGSGPTIEE VD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hspa1b

Associated with

Other Information

Characterization and sequence of a mouse hsp70 gene and its expression in mouse cell lines. PubMed ID: 2332169

Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. PubMed ID: 14656967

CatSperbeta, a novel transmembrane protein in the CatSper channel complex. PubMed ID: 17478420

A novel, single, transmembrane protein CATSPERG is associated with CATSPER1 channel protein. PubMed ID: 19516020

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079