Details for: Ndst1

Gene ID: 15531

Symbol: Ndst1

Ensembl ID: ENSMUSG00000054008

Description: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

Associated with

Other Information

Genular Protein ID: 3345322309

Symbol: NDST1_MOUSE

Name: Glucosaminyl N-deacetylase/N-sulfotransferase 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9565617

Title: Identification and expression in mouse of two heparan sulfate glucosaminyl N-deacetylase/N-sulfotransferase genes.

PubMed ID: 9565617

DOI: 10.1074/jbc.273.19.11902

PubMed ID: 11087757

Title: Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4.

PubMed ID: 11087757

DOI: 10.1074/jbc.m009606200

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10758005

Title: Overexpression of different isoforms of glucosaminyl N-deacetylase/N-sulfotransferase results in distinct heparan sulfate N-sulfation patterns.

PubMed ID: 10758005

DOI: 10.1021/bi992524l

PubMed ID: 10664446

Title: Targeted disruption of NDST-1 gene leads to pulmonary hypoplasia and neonatal respiratory distress in mice.

PubMed ID: 10664446

DOI: 10.1016/s0014-5793(00)01111-x

PubMed ID: 10852901

Title: Defective heparan sulfate biosynthesis and neonatal lethality in mice lacking N-deacetylase/N-sulfotransferase-1.

PubMed ID: 10852901

DOI: 10.1074/jbc.c000359200

PubMed ID: 12590599

Title: Distinct effects on heparan sulfate structure by different active site mutations in NDST-1.

PubMed ID: 12590599

DOI: 10.1021/bi026928g

PubMed ID: 12634318

Title: Antibody-based assay for N-deacetylase activity of heparan sulfate/heparin N-deacetylase/N-sulfotransferase (NDST): novel characteristics of NDST-1 and -2.

PubMed ID: 12634318

DOI: 10.1093/glycob/cwg011

PubMed ID: 12692154

Title: Disturbed Ca2+ kinetics in N-deacetylase/N-sulfotransferase-1 defective myotubes.

PubMed ID: 12692154

DOI: 10.1242/jcs.00447

PubMed ID: 16020517

Title: Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function.

PubMed ID: 16020517

DOI: 10.1242/dev.01935

PubMed ID: 16056228

Title: Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses.

PubMed ID: 16056228

DOI: 10.1038/ni1233

PubMed ID: 18337501

Title: Heparan sulfate biosynthesis enzymes EXT1 and EXT2 affect NDST1 expression and heparan sulfate sulfation.

PubMed ID: 18337501

DOI: 10.1073/pnas.0705807105

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 882
  • Mass: 100726
  • Checksum: 8BE300ABCB8E648D
  • Sequence:
  • MPALACLRRL CRHLSPQAVL FLLFVFCLFS VFVSAYYLYG WNRGLEPSAD ASESDCGDPP 
    PVAPSRLLPI KPVQAVAPSR TDPLVLVFVE SLYSQLGQEV VAILESSRFK YRTEIAPGKG 
    DMPTLTDKGR GRFALIIYEN ILKYVNLDAW NRELLDKYCV AYGVGIIGFF KANENSLLSA 
    QLKGFPLFLH SNLGLKDCSI NPKSPLLYVT RPSEVEKGVL PGEDWTVFQS NHSTYEPVLL 
    AKTRSSESIP HLGADAGLHA ALHATVVQDL GLHDGIQRVL FGNNLNFWLH KLVFVDAVAF 
    LTGKRLSLPL DRYILVDIDD IFVGKEGTRM KVEDVKALFD TQNELRTHIP NFTFNLGYSG 
    KFFHTGTDAE DAGDDLLLSY VKEFWWFPHM WSHMQPHLFH NQSVLAEQMA LNKKFAVEHG 
    IPTDMGYAVA PHHSGVYPVH VQLYEAWKQV WGIRVTSTEE YPHLKPARYR RGFIHNGIMV 
    LPRQTCGLFT HTIFYNEYPG GSSELDKIIN GGELFLTVLL NPISIFMTHL SNYGNDRLGL 
    YTFKHLVRFL HSWTNLRLQT LPPVQLAQKY FQIFSEEKDP LWQDPCEDKR HKDIWSKEKT 
    CDRFPKLLII GPQKTGTTAL YLFLGMHPDL SSNYPSSETF EEIQFFNGHN YHKGIDWYME 
    FFPIPSNTTS DFYFEKSANY FDSEVAPRRA AALLPKAKIL SILINPADRA YSWYQHQRAH 
    DDPVALKYTF HEVITAGPDA SSKLRALQNR CLVPGWYATH IERWLSAFHA NQILVLDGKL 
    LRTEPAKVMD TVQKFLGVTS TVDYHKTLAF DPKKGFWCQL LEGGKTKCLG KSKGRKYPEM 
    DLDSRAFLKD YFRDHNIELS KLLYKMGQTL PTWLREDLQN TR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.