Details for: CYP2B6

Gene ID: 1555

Symbol: CYP2B6

Ensembl ID: ENSG00000197408

Description: cytochrome P450 family 2 subfamily B member 6

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 14.1322
    Cell Significance Index: 37.2800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 13.2603
    Cell Significance Index: 223.3700
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 10.9152
    Cell Significance Index: 101.3000
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.4688
    Cell Significance Index: 21.6800
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 1.0780
    Cell Significance Index: 4.0600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.8415
    Cell Significance Index: 160.1400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6595
    Cell Significance Index: 39.5900
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.5051
    Cell Significance Index: 5.2100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4481
    Cell Significance Index: 12.9100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4399
    Cell Significance Index: 9.5300
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.3673
    Cell Significance Index: 2.1200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3589
    Cell Significance Index: 39.0400
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.2976
    Cell Significance Index: 3.7600
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 0.2856
    Cell Significance Index: 0.7700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.2810
    Cell Significance Index: 4.2100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2597
    Cell Significance Index: 11.7700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2450
    Cell Significance Index: 24.2400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2437
    Cell Significance Index: 220.0600
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 0.2331
    Cell Significance Index: 1.8400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.2221
    Cell Significance Index: 5.9500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2143
    Cell Significance Index: 14.8200
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: 0.2000
    Cell Significance Index: 0.4400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1578
    Cell Significance Index: 25.6700
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.1209
    Cell Significance Index: 1.0400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1175
    Cell Significance Index: 4.1300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0998
    Cell Significance Index: 19.8100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0657
    Cell Significance Index: 1.4000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0628
    Cell Significance Index: 2.0100
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0478
    Cell Significance Index: 0.5000
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.0419
    Cell Significance Index: 0.6900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0408
    Cell Significance Index: 1.0200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0318
    Cell Significance Index: 0.6600
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.0275
    Cell Significance Index: 0.2100
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.0155
    Cell Significance Index: 0.2600
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.0116
    Cell Significance Index: 0.1100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0032
    Cell Significance Index: 1.7700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0003
    Cell Significance Index: -0.1900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0009
    Cell Significance Index: -1.7400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0010
    Cell Significance Index: -1.8700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0010
    Cell Significance Index: -1.4800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0013
    Cell Significance Index: -1.8000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0023
    Cell Significance Index: -0.4700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0028
    Cell Significance Index: -2.1100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0031
    Cell Significance Index: -1.1300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0034
    Cell Significance Index: -1.9500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0051
    Cell Significance Index: -0.2100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0055
    Cell Significance Index: -4.0000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0060
    Cell Significance Index: -0.7000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0063
    Cell Significance Index: -4.0000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0079
    Cell Significance Index: -3.5900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0082
    Cell Significance Index: -2.3700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0091
    Cell Significance Index: -1.5500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0098
    Cell Significance Index: -0.4900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0101
    Cell Significance Index: -0.2600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0107
    Cell Significance Index: -1.4700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0112
    Cell Significance Index: -2.3500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0113
    Cell Significance Index: -1.2900
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.0116
    Cell Significance Index: -0.1100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0134
    Cell Significance Index: -0.8200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0156
    Cell Significance Index: -0.4400
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.0173
    Cell Significance Index: -0.1900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0176
    Cell Significance Index: -3.1700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0180
    Cell Significance Index: -0.6300
  • Cell Name: colonocyte (CL1000347)
    Fold Change: -0.0210
    Cell Significance Index: -0.1300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0212
    Cell Significance Index: -2.7400
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.0226
    Cell Significance Index: -0.1400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0227
    Cell Significance Index: -2.3600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0247
    Cell Significance Index: -3.5900
  • Cell Name: inflammatory macrophage (CL0000863)
    Fold Change: -0.0273
    Cell Significance Index: -0.2100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0286
    Cell Significance Index: -2.1300
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.0289
    Cell Significance Index: -0.4000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0292
    Cell Significance Index: -3.5900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0306
    Cell Significance Index: -3.1300
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0319
    Cell Significance Index: -0.4800
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: -0.0341
    Cell Significance Index: -0.2400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0347
    Cell Significance Index: -2.3300
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: -0.0350
    Cell Significance Index: -0.3200
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: -0.0352
    Cell Significance Index: -0.4100
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0361
    Cell Significance Index: -0.5000
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0370
    Cell Significance Index: -0.3900
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -0.0433
    Cell Significance Index: -0.3800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0461
    Cell Significance Index: -1.5100
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.0490
    Cell Significance Index: -0.4200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0492
    Cell Significance Index: -3.9000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0496
    Cell Significance Index: -1.5800
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.0502
    Cell Significance Index: -0.3400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0515
    Cell Significance Index: -2.8900
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: -0.0517
    Cell Significance Index: -0.5100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0521
    Cell Significance Index: -1.4200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0533
    Cell Significance Index: -0.6100
  • Cell Name: precursor cell (CL0011115)
    Fold Change: -0.0541
    Cell Significance Index: -0.4100
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.0578
    Cell Significance Index: -0.4200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0591
    Cell Significance Index: -3.6300
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: -0.0593
    Cell Significance Index: -0.4900
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: -0.0630
    Cell Significance Index: -0.3300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0631
    Cell Significance Index: -2.7900
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: -0.0644
    Cell Significance Index: -0.4000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0657
    Cell Significance Index: -1.6400
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0661
    Cell Significance Index: -2.0900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** CYP2B6 is a member of the cytochrome P450 family, which is characterized by the presence of a heme group and a flavin moiety. The enzyme is a monooxygenase, meaning it catalyzes the incorporation of one atom of oxygen into a substrate. CYP2B6 is a cytochrome P450 enzyme, which means it contains a heme group and is involved in the oxidation of substrates. The enzyme is also a member of the CYP2 subfamily, which is characterized by the presence of a specific amino acid sequence. **Pathways and Functions** CYP2B6 is involved in the metabolism of a wide range of substrates, including: * Anandamide: CYP2B6 catalyzes the epoxidation of anandamide, a cannabinoid neurotransmitter, to form 11,12-dihydroanandamide. * Arachidonic acid: CYP2B6 catalyzes the epoxidation of arachidonic acid to form epoxyeicosatrienoic acid (EET), which is involved in various cellular processes, including inflammation and cell signaling. * Xenobiotics: CYP2B6 is involved in the metabolism of various xenobiotics, including drugs, such as cyclophosphamide and carbamazepine, and environmental toxins, such as polycyclic aromatic hydrocarbons (PAHs). * Steroids: CYP2B6 is involved in the metabolism of various steroids, including testosterone and estrogen. **Clinical Significance** CYP2B6 is involved in the metabolism of various drugs, including: * Cyclophosphamide: CYP2B6 is involved in the metabolism of cyclophosphamide, a chemotherapeutic agent, and its metabolite, acrolein, which can cause toxicity. * Carbamazepine: CYP2B6 is involved in the metabolism of carbamazepine, an anticonvulsant agent, and its metabolite, phenylacetylglutamine, which can cause toxicity. * Methadone: CYP2B6 is involved in the metabolism of methadone, an opioid analgesic, and its metabolite, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), which can cause toxicity. * Cannabinoids: CYP2B6 is involved in the metabolism of cannabinoids, including THC, the active metabolite of cannabis. Polymorphisms in the CYP2B6 gene can affect the metabolism of these drugs and may contribute to adverse drug reactions. Therefore, CYP2B6 is an important enzyme in the context of pharmacogenomics and personalized medicine. In addition to its role in drug metabolism, CYP2B6 is also involved in the regulation of various cellular processes, including inflammation, cell signaling, and metabolism. Alterations in CYP2B6 expression or activity may contribute to various diseases, including cancer, cardiovascular disease, and neurological disorders. In conclusion, CYP2B6 is an important enzyme involved in the metabolism of a wide range of substrates, including drugs, hormones, and toxins. Its polymorphisms can affect the metabolism of drugs and may contribute to adverse drug reactions. Further research is needed to fully understand the role of CYP2B6 in human health and disease.

Genular Protein ID: 3336004032

Symbol: CP2B6_HUMAN

Name: Cytochrome P450 2B6

UniProtKB Accession Codes:

P20813 B4DWP3 Q2V565 Q9UK46

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 59 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 100 DrugCentral 1 EMBL 7 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 19 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 2 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 13 PIR 1 PRINTS 3 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 4 RefSeq 2 Rhea 32 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 2573390

Title: cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver.

PubMed ID: 2573390

DOI: 10.1021/bi00444a029

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 2813061

Title: Alternative splicing in the human cytochrome P450IIB6 gene generates a high level of aberrant messages.

PubMed ID: 2813061

DOI: 10.1093/nar/17.20.8241

PubMed ID: 10768437

Title: Gene expression in distinct regions of the heart.

PubMed ID: 10768437

DOI: 10.1016/s0140-6736(00)99016-0

PubMed ID: 11695850

Title: Roles of cytochrome P450 3A enzymes in the 2-hydroxylation of 1,4-cineole, a monoterpene cyclic ether, by rat and human liver microsomes.

PubMed ID: 11695850

DOI: 10.1080/00498250110065595

PubMed ID: 12865317

Title: Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms.

PubMed ID: 12865317

DOI: 10.1210/en.2003-0192

PubMed ID: 21289075

Title: Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6.

PubMed ID: 21289075

DOI: 10.1124/dmd.110.036707

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 20061448

Title: Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl)imidazole at 2.0-A resolution.

PubMed ID: 20061448

DOI: 10.1124/mol.109.062570

PubMed ID: 21875942

Title: Structures of cytochrome P450 2B6 bound to 4-benzylpyridine and 4-(4-nitrobenzyl)pyridine: insight into inhibitor binding and rearrangement of active site side chains.

PubMed ID: 21875942

DOI: 10.1124/mol.111.074427

PubMed ID: 22909231

Title: Conformational adaptation of human cytochrome P450 2B6 and rabbit cytochrome P450 2B4 revealed upon binding multiple amlodipine molecules.

PubMed ID: 22909231

DOI: 10.1021/bi300894z

PubMed ID: 15622315

Title: Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study.

PubMed ID: 15622315

PubMed ID: 15194512

Title: Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens.

PubMed ID: 15194512

DOI: 10.1016/j.bbrc.2004.05.116

PubMed ID: 20639527

Title: Haplotype structure of CYP2B6 and association with plasma efavirenz concentrations in a Chilean HIV cohort.

PubMed ID: 20639527

DOI: 10.1093/jac/dkq260

PubMed ID: 20860463

Title: Influence of host genetic factors on efavirenz plasma and intracellular pharmacokinetics in HIV-1-infected patients.

PubMed ID: 20860463

DOI: 10.2217/pgs.10.94

PubMed ID: 11243870

Title: A single nucleotide polymorphism of CYP2b6 found in Japanese enhances catalytic activity by autoactivation.

PubMed ID: 11243870

DOI: 10.1006/bbrc.2001.4524

PubMed ID: 11470993

Title: Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver.

PubMed ID: 11470993

DOI: 10.1097/00008571-200107000-00004

PubMed ID: 12642465

Title: Functional characterization of cytochrome P450 2B6 allelic variants.

PubMed ID: 12642465

DOI: 10.1124/dmd.31.4.398

PubMed ID: 12721789

Title: Catalog of 680 variations among eight cytochrome p450 (CYP) genes, nine esterase genes, and two other genes in the Japanese population.

PubMed ID: 12721789

DOI: 10.1007/s10038-003-0021-7

PubMed ID: 14551287

Title: Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression.

PubMed ID: 14551287

DOI: 10.1124/jpet.103.054866

PubMed ID: 15190123

Title: Multiple novel nonsynonymous CYP2B6 gene polymorphisms in Caucasians: demonstration of phenotypic null alleles.

PubMed ID: 15190123

DOI: 10.1124/jpet.104.068973

PubMed ID: 15469410

Title: Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population.

PubMed ID: 15469410

DOI: 10.1517/14622416.5.7.895

Sequence Information:

  • Length: 491
  • Mass: 56278
  • Checksum: B9799164BE8FBF1D
  • Sequence:
    • MELSVLLFLA LLTGLLLLLV QRHPNTHDRL PPGPRPLPLL GNLLQMDRRG LLKSFLRFRE 
KYGDVFTVHL GPRPVVMLCG VEAIREALVD KAEAFSGRGK IAMVDPFFRG YGVIFANGNR 
WKVLRRFSVT TMRDFGMGKR SVEERIQEEA QCLIEELRKS KGALMDPTFL FQSITANIIC 
SIVFGKRFHY QDQEFLKMLN LFYQTFSLIS SVFGQLFELF SGFLKYFPGA HRQVYKNLQE 
INAYIGHSVE KHRETLDPSA PKDLIDTYLL HMEKEKSNAH SEFSHQNLNL NTLSLFFAGT 
ETTSTTLRYG FLLMLKYPHV AERVYREIEQ VIGPHRPPEL HDRAKMPYTE AVIYEIQRFS 
DLLPMGVPHI VTQHTSFRGY IIPKDTEVFL ILSTALHDPH YFEKPDAFNP DHFLDANGAL 
KKTEAFIPFS LGKRICLGEG IARAELFLFF TTILQNFSMA SPVAPEDIDL TPQECGVGKI 
PPTYQIRFLP R

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.