Genular: Defining Cellular Identity and Function

Details for: Htr6

Gene ID: 15565

Symbol: Htr6

Ensembl ID: ENSMUSG00000028747

Description: 5-hydroxytryptamine (serotonin) receptor 6

Associated with

Amine ligand-binding receptors
(R-MMU-375280)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (s) signalling events
(R-MMU-418555)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Serotonin receptors
(R-MMU-390666)
Signaling by gpcr
(R-MMU-372790)
Cerebral cortex cell migration
(GO:0021795)
Chemical synaptic transmission
(GO:0007268)
Cilium
(GO:0005929)
Dendrite
(GO:0030425)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
(GO:0007187)
G protein-coupled serotonin receptor activity
(GO:0004993)
Learning
(GO:0007612)
Long-term synaptic potentiation
(GO:0060291)
Membrane
(GO:0016020)
Negative regulation of acetylcholine secretion, neurotransmission
(GO:0014058)
Negative regulation of gamma-aminobutyric acid secretion
(GO:0014053)
Negative regulation of glutamate secretion
(GO:0014050)
Neurotransmitter receptor activity
(GO:0030594)
Plasma membrane
(GO:0005886)
Positive regulation of dopamine secretion
(GO:0033603)
Positive regulation of gamma-aminobutyric acid secretion
(GO:0014054)
Positive regulation of tor signaling
(GO:0032008)
Protein binding
(GO:0005515)
Signal transduction
(GO:0007165)

Other Information

Proteins

5-hydroxytryptamine receptor 6

Genular Protein ID: 2239565225

Symbol: 5HT6R_MOUSE

Name: 5-hydroxytryptamine receptor 6

UniProtKB Accession Codes:

Q9R1C8

Database IDs:

Citations:

PubMed ID: 11406289

Title: Cloning of the mouse 5-HT6 serotonin receptor and mutagenesis studies of the third cytoplasmic loop.

PubMed ID: 11406289

DOI: 10.1016/s0169-328x(01)00090-0

PubMed ID: 23027611

Title: 5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.

PubMed ID: 23027611

DOI: 10.1002/emmm.201201410

PubMed ID: 25078650

Title: The serotonin 6 receptor controls neuronal migration during corticogenesis via a ligand-independent Cdk5-dependent mechanism.

PubMed ID: 25078650

DOI: 10.1242/dev.108043

Sequence Information:

Length: 440
Mass: 46998
Checksum: 4440CDEBE01FEF0C
Sequence:

MVPEPGPVNS STPAWGPGPP PAPGGSGWVA AALCVVIVLT AAANSLLIAL ICTQPALRNT 
SNFFLVSLFT SDLMVGLVVM PPAMLNALYG RWVLARGLCL LWTAFDVMCC SASILNLCLI 
SLDRYLLILS PLRYKLRMTA PRALALILGA WSLAALASFL PLLLGWHELG KARTSAPGQC 
RLLASLPYVL VASGVTFFLP SGAICFTYCR ILLAARKQAV QVASLTTGTA TAGQALETLQ 
VPRTPRPGME SADSRRLTTK HSRKALKASL TLGILLSMFF VTWLPFFVAS IAQAVCDCIS 
PGLFDVLTWL GYCNSTMNPI IYPLFMRDFK RALGRFVPCV HCPPEHRASP ASPSMWTSHS 
GARPGLSLQQ VLPLPLPPNS DSDSASGGTS GLQLTAQLLL PGEATRDPPP PTRAPTVVNF 
FVTDSVEPEI RQHPLGSPMN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.