Genular: Defining Cellular Identity and Function

Details for: Hus1

Gene ID: 15574

Symbol: Hus1

Ensembl ID: ENSMUSG00000020413

Description: HUS1 checkpoint clamp component

Associated with

Activation of atr in response to replication stress
(R-MMU-176187)
Cell cycle
(R-MMU-1640170)
Cell cycle checkpoints
(R-MMU-69620)
Dna double-strand break repair
(R-MMU-5693532)
Dna repair
(R-MMU-73894)
G2/m checkpoints
(R-MMU-69481)
G2/m dna damage checkpoint
(R-MMU-69473)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Hdr through homologous recombination (hrr) or single strand annealing (ssa)
(R-MMU-5693567)
Hdr through single strand annealing (ssa)
(R-MMU-5685938)
Homology directed repair
(R-MMU-5693538)
Processing of dna double-strand break ends
(R-MMU-5693607)
Regulation of tp53 activity
(R-MMU-5633007)
Regulation of tp53 activity through phosphorylation
(R-MMU-6804756)
Rna polymerase ii transcription
(R-MMU-73857)
Transcriptional regulation by tp53
(R-MMU-3700989)
Cellular response to ionizing radiation
(GO:0071479)
Checkpoint clamp complex
(GO:0030896)
Cytoplasm
(GO:0005737)
Dna damage checkpoint signaling
(GO:0000077)
Dna damage response
(GO:0006974)
Double-strand break repair via homologous recombination
(GO:0000724)
Embryo development ending in birth or egg hatching
(GO:0009792)
Meiotic dna integrity checkpoint signaling
(GO:0044778)
Mitotic dna replication checkpoint signaling
(GO:0033314)
Mitotic intra-s dna damage checkpoint signaling
(GO:0031573)
Nucleolus
(GO:0005730)
Nucleotide-excision repair
(GO:0006289)
Nucleus
(GO:0005634)
Protein phosphorylation
(GO:0006468)
Regulation of protein phosphorylation
(GO:0001932)
Response to uv
(GO:0009411)
Site of double-strand break
(GO:0035861)
Telomere maintenance
(GO:0000723)

Other Information

Proteins

Checkpoint protein HUS1

Genular Protein ID: 1399681125

Symbol: HUS1_MOUSE

Name: Checkpoint protein HUS1

UniProtKB Accession Codes:

Q8BQY8 O70543 Q6P8H5

Database IDs:

Citations:

PubMed ID: 9878245

Title: cDNA cloning and gene mapping of human homologs for Schizosaccharomyces pombe rad17, rad1, and hus1 and cloning of homologs from mouse, Caenorhabditis elegans, and Drosophila melanogaster.

PubMed ID: 9878245

DOI: 10.1006/geno.1998.5587

PubMed ID: 10395797

Title: Mouse Hus1, a homologue of the Schizosaccharomyces pombe hus1+ cell cycle checkpoint gene.

PubMed ID: 10395797

DOI: 10.1006/geno.1999.5865

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 280
Mass: 31680
Checksum: 8721B79853E6150D
Sequence:

MKFRAKIVDL ACLNHFTRVS NMIAKLAKTC TLRISPEKLN FILCDKLASG GVSMWCELEQ 
ENFFSEFQME GVSEENNEIY LELTSENLSR ALKTAQNSRA LKIKLTNKHF PCLTVSVELV 
SSSSSSRIVV HDIPIKVLPR RLWKDLQEPS IPDCDVSICL PALKMMKSVV EKMRNISNQL 
VIEANLKGEL NLKIETELVC VTTHFKDLEN PLLPSDSVSQ NRHPEDMAKV HIDIKKLLQF 
LAGQQVTPTK AVCNIVNNRT VHFDLLLEDV SLQYFIPALS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hus1

Associated with

Other Information

cDNA cloning and gene mapping of human homologs for Schizosaccharomyces pombe rad17, rad1, and hus1 and cloning of homologs from mouse, Caenorhabditis elegans, and Drosophila melanogaster. PubMed ID: 9878245

Mouse Hus1, a homologue of the Schizosaccharomyces pombe hus1+ cell cycle checkpoint gene. PubMed ID: 10395797

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072