Details for: CYP2F1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 9.0128
Cell Significance Index: 92.9700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 5.6773
Cell Significance Index: -1.4400 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.6676
Cell Significance Index: 25.8000 - Cell Name: tracheal goblet cell (CL1000329)
Fold Change: 1.1099
Cell Significance Index: 9.1800 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 0.2929
Cell Significance Index: 2.5200 - Cell Name: germ cell (CL0000586)
Fold Change: 0.2662
Cell Significance Index: 2.0100 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.1796
Cell Significance Index: 2.3200 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.1704
Cell Significance Index: 2.4400 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.1668
Cell Significance Index: 2.3900 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 0.1494
Cell Significance Index: 1.5900 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 0.0627
Cell Significance Index: 0.6500 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 0.0346
Cell Significance Index: 0.2300 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.0217
Cell Significance Index: 0.2800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0098
Cell Significance Index: 7.4400 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 0.0084
Cell Significance Index: 0.1100 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: 0.0004
Cell Significance Index: 0.0000 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.0000
Cell Significance Index: 0.0000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0001
Cell Significance Index: -0.2100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0004
Cell Significance Index: -0.7300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0005
Cell Significance Index: -0.7100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0006
Cell Significance Index: -0.8600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0011
Cell Significance Index: -0.2200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0012
Cell Significance Index: -0.3400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0019
Cell Significance Index: -0.6800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0020
Cell Significance Index: -1.2400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0020
Cell Significance Index: -1.4800 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0023
Cell Significance Index: -1.2600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0026
Cell Significance Index: -1.4400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0029
Cell Significance Index: -0.0400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0030
Cell Significance Index: -1.3400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0030
Cell Significance Index: -0.5900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0036
Cell Significance Index: -0.6100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0069
Cell Significance Index: -1.4500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0070
Cell Significance Index: -1.2600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0070
Cell Significance Index: -0.9600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0072
Cell Significance Index: -1.0400 - Cell Name: secretory cell (CL0000151)
Fold Change: -0.0072
Cell Significance Index: -0.0500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0074
Cell Significance Index: -0.8600 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: -0.0094
Cell Significance Index: -0.1300 - Cell Name: club cell (CL0000158)
Fold Change: -0.0101
Cell Significance Index: -0.1100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0101
Cell Significance Index: -1.1600 - Cell Name: goblet cell (CL0000160)
Fold Change: -0.0111
Cell Significance Index: -0.1000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0113
Cell Significance Index: -1.3900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0116
Cell Significance Index: -0.3100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0124
Cell Significance Index: -1.2700 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0137
Cell Significance Index: -0.3600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0142
Cell Significance Index: -1.6800 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0144
Cell Significance Index: -0.5300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0168
Cell Significance Index: -0.8500 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.0188
Cell Significance Index: -0.4700 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0206
Cell Significance Index: -0.8400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0208
Cell Significance Index: -1.4000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0209
Cell Significance Index: -1.3500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0216
Cell Significance Index: -1.1200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0217
Cell Significance Index: -1.0100 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.0223
Cell Significance Index: -0.5400 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: -0.0225
Cell Significance Index: -0.2500 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0228
Cell Significance Index: -0.5000 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: -0.0230
Cell Significance Index: -0.2800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0241
Cell Significance Index: -0.6700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0251
Cell Significance Index: -0.6500 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.0281
Cell Significance Index: -0.4000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0284
Cell Significance Index: -0.9100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0284
Cell Significance Index: -1.3400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0289
Cell Significance Index: -0.9500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0303
Cell Significance Index: -0.8100 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0309
Cell Significance Index: -0.5300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.0312
Cell Significance Index: -0.9000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0319
Cell Significance Index: -1.4100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0323
Cell Significance Index: -1.8100 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: -0.0348
Cell Significance Index: -0.1900 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: -0.0359
Cell Significance Index: -0.3300 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0361
Cell Significance Index: -0.9000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0367
Cell Significance Index: -1.3900 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0386
Cell Significance Index: -1.2200 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0400
Cell Significance Index: -1.4000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0408
Cell Significance Index: -1.4400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0446
Cell Significance Index: -1.2900 - Cell Name: lung goblet cell (CL1000143)
Fold Change: -0.0448
Cell Significance Index: -0.4400 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: -0.0449
Cell Significance Index: -0.4500 - Cell Name: basal cell (CL0000646)
Fold Change: -0.0462
Cell Significance Index: -0.5500 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0463
Cell Significance Index: -1.2600 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: -0.0467
Cell Significance Index: -0.6800 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.0499
Cell Significance Index: -1.4700 - Cell Name: epithelial cell (CL0000066)
Fold Change: -0.0502
Cell Significance Index: -0.5300 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.0505
Cell Significance Index: -0.8700 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0509
Cell Significance Index: -1.3000 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.0510
Cell Significance Index: -1.3000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0522
Cell Significance Index: -1.4900 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.0527
Cell Significance Index: -1.0500 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: -0.0539
Cell Significance Index: -0.5500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0547
Cell Significance Index: -1.4600 - Cell Name: ciliated cell (CL0000064)
Fold Change: -0.0554
Cell Significance Index: -0.6000 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0556
Cell Significance Index: -1.1800 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.0562
Cell Significance Index: -1.6500 - Cell Name: airway submucosal gland collecting duct epithelial cell (CL4033023)
Fold Change: -0.0570
Cell Significance Index: -0.4000 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.0577
Cell Significance Index: -1.4400 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.0579
Cell Significance Index: -1.2500 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: -0.0584
Cell Significance Index: -0.6900 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.0592
Cell Significance Index: -1.2400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1847476192
Symbol: CP2F1_HUMAN
Name: Cytochrome P450 2F1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1974816
Title: The human CYP2F gene subfamily: identification of a cDNA encoding a new cytochrome P450, cDNA-directed expression, and chromosome mapping.
PubMed ID: 1974816
DOI: 10.1021/bi00475a012
PubMed ID: 11827709
Title: Identification and cross-species comparisons of CYP2F subfamily genes in mammals.
PubMed ID: 11827709
PubMed ID: 17327131
Title: Molecular analysis of the CYP2F1 gene: identification of a frequent non-functional allelic variant.
PubMed ID: 17327131
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8619884
Title: Expression of xenobiotic-metabolizing cytochrome P450 forms in human full-term placenta.
PubMed ID: 8619884
PubMed ID: 8558432
Title: Metabolism of 3-methylindole by vaccinia-expressed P450 enzymes: correlation of 3-methyleneindolenine formation and protein-binding.
PubMed ID: 8558432
PubMed ID: 10383923
Title: Specific dehydrogenation of 3-methylindole and epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells.
PubMed ID: 10383923
Sequence Information:
- Length: 491
- Mass: 55501
- Checksum: D8022271FC0B6D06
- Sequence:
MDSISTAILL LLLALVCLLL TLSSRDKGKL PPGPRPLSIL GNLLLLCSQD MLTSLTKLSK EYGSMYTVHL GPRRVVVLSG YQAVKEALVD QGEEFSGRGD YPAFFNFTKG NGIAFSSGDR WKVLRQFSIQ ILRNFGMGKR SIEERILEEG SFLLAELRKT EGEPFDPTFV LSRSVSNIIC SVLFGSRFDY DDERLLTIIR LINDNFQIMS SPWGELYDIF PSLLDWVPGP HQRIFQNFKC LRDLIAHSVH DHQASLDPRS PRDFIQCFLT KMAEEKEDPL SHFHMDTLLM TTHNLLFGGT KTVSTTLHHA FLALMKYPKV QARVQEEIDL VVGRARLPAL KDRAAMPYTD AVIHEVQRFA DIIPMNLPHR VTRDTAFRGF LIPKGTDVIT LLNTVHYDPS QFLTPQEFNP EHFLDANQSF KKSPAFMPFS AGRRLCLGES LARMELFLYL TAILQSFSLQ PLGAPEDIDL TPLSSGLGNL PRPFQLCLRP R
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.