Details for: CYP3A5

Gene ID: 1577

Symbol: CYP3A5

Ensembl ID: ENSG00000106258

Description: cytochrome P450 family 3 subfamily A member 5

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 67.6974
    Cell Significance Index: -10.5300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 41.4756
    Cell Significance Index: -10.5200
  • Cell Name: epithelial cell of exocrine pancreas (CL1001433)
    Fold Change: 32.8348
    Cell Significance Index: 16.4900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 14.6928
    Cell Significance Index: 247.5000
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 13.2203
    Cell Significance Index: 100.2500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 8.9249
    Cell Significance Index: 257.1500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 8.8405
    Cell Significance Index: -10.9000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 6.3881
    Cell Significance Index: 95.7200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 5.9112
    Cell Significance Index: 307.0700
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 5.8598
    Cell Significance Index: 33.7500
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 5.3185
    Cell Significance Index: 14.0300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 4.9734
    Cell Significance Index: 225.4300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 4.8062
    Cell Significance Index: 130.8200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 4.6382
    Cell Significance Index: 320.7600
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 4.6234
    Cell Significance Index: 46.6400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.2443
    Cell Significance Index: -11.3700
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 3.8280
    Cell Significance Index: 64.3900
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 2.7072
    Cell Significance Index: 29.3400
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 2.5829
    Cell Significance Index: 15.9800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.3767
    Cell Significance Index: 51.4900
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 2.0727
    Cell Significance Index: 21.4500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.0679
    Cell Significance Index: 410.3800
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 1.9436
    Cell Significance Index: 7.3200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.9214
    Cell Significance Index: 190.0700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.8075
    Cell Significance Index: 196.6100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 1.4090
    Cell Significance Index: 49.5100
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.2944
    Cell Significance Index: 11.4900
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 1.2765
    Cell Significance Index: 7.9000
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.2643
    Cell Significance Index: 7.8000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.2504
    Cell Significance Index: 33.5100
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.2437
    Cell Significance Index: 12.2700
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.1674
    Cell Significance Index: 17.2300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.1501
    Cell Significance Index: 32.1400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9401
    Cell Significance Index: 152.8900
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.8211
    Cell Significance Index: 13.5300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5685
    Cell Significance Index: 513.2900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.4939
    Cell Significance Index: 9.6400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.4404
    Cell Significance Index: 9.3800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.4297
    Cell Significance Index: 49.0500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.4148
    Cell Significance Index: 3.8200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3487
    Cell Significance Index: 66.3500
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 0.2708
    Cell Significance Index: 3.4100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.2639
    Cell Significance Index: 3.6000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2435
    Cell Significance Index: 29.9500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.2409
    Cell Significance Index: 27.6000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.2224
    Cell Significance Index: 13.6700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2049
    Cell Significance Index: 36.9400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1653
    Cell Significance Index: 12.6900
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.1627
    Cell Significance Index: 3.7600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1496
    Cell Significance Index: 30.0100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.1138
    Cell Significance Index: 3.6500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.1109
    Cell Significance Index: 2.8500
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.0838
    Cell Significance Index: 0.3700
  • Cell Name: colonocyte (CL1000347)
    Fold Change: 0.0825
    Cell Significance Index: 0.5100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0796
    Cell Significance Index: 43.4600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0542
    Cell Significance Index: 19.4300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.0480
    Cell Significance Index: 1.1500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0478
    Cell Significance Index: 0.5700
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.0462
    Cell Significance Index: 0.7100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0249
    Cell Significance Index: 7.1700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0241
    Cell Significance Index: 3.5100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0236
    Cell Significance Index: 4.0300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0167
    Cell Significance Index: 30.8200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0162
    Cell Significance Index: 24.9700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0150
    Cell Significance Index: 0.7900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0126
    Cell Significance Index: 17.1400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0116
    Cell Significance Index: 21.8000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0036
    Cell Significance Index: 0.4600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0007
    Cell Significance Index: -0.1000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0016
    Cell Significance Index: -1.1800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0023
    Cell Significance Index: -1.4600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0035
    Cell Significance Index: -1.5900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0039
    Cell Significance Index: -1.7200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0050
    Cell Significance Index: -3.1700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0086
    Cell Significance Index: -4.8700
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0130
    Cell Significance Index: -0.4100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0131
    Cell Significance Index: -9.5900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0135
    Cell Significance Index: -10.2300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0200
    Cell Significance Index: -4.2100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0218
    Cell Significance Index: -2.2300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0263
    Cell Significance Index: -0.4500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0308
    Cell Significance Index: -0.7700
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.0473
    Cell Significance Index: -0.3400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0489
    Cell Significance Index: -3.0800
  • Cell Name: urothelial cell (CL0000731)
    Fold Change: -0.0516
    Cell Significance Index: -0.3600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0517
    Cell Significance Index: -6.0200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0597
    Cell Significance Index: -3.3500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0651
    Cell Significance Index: -4.3800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0656
    Cell Significance Index: -8.4700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0722
    Cell Significance Index: -3.6500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0726
    Cell Significance Index: -3.2100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0829
    Cell Significance Index: -3.1400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0883
    Cell Significance Index: -9.1900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0895
    Cell Significance Index: -6.3300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0915
    Cell Significance Index: -10.7900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1021
    Cell Significance Index: -7.6100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1034
    Cell Significance Index: -1.7300
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1067
    Cell Significance Index: -2.6600
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.1073
    Cell Significance Index: -0.7800
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.1151
    Cell Significance Index: -0.8800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CYP3A5 is a non-steroidal member of the cytochrome P450 superfamily, characterized by its ability to catalyze monooxygenase reactions. The gene is highly conserved across species, with a high degree of sequence similarity to other cytochrome P450 enzymes. The CYP3A5 enzyme is a heme-containing protein, which is essential for its catalytic activity. The gene is transcribed in the nucleus and translated into a polypeptide chain, which is then inserted into the endoplasmic reticulum membrane. **Pathways and Functions:** The CYP3A5 enzyme is involved in the metabolism of a wide range of substances, including: 1. **Xenobiotics:** CYP3A5 plays a critical role in the detoxification of xenobiotics, such as drugs, pesticides, and environmental pollutants. 2. **Steroids:** The enzyme is involved in the metabolism of steroids, including testosterone and estrogen, which are essential for various physiological processes. 3. **Endogenous compounds:** CYP3A5 also metabolizes endogenous compounds, such as retinoids and retinoic acid, which are involved in cell growth and differentiation. 4. **Aflatoxin activation:** The enzyme is involved in the activation of aflatoxins, which are potent carcinogens produced by certain fungi. The CYP3A5 enzyme is also involved in various cellular processes, including: 1. **Heme binding:** The enzyme binds heme, which is essential for its catalytic activity. 2. **Oxidative demethylation:** CYP3A5 is involved in the oxidative demethylation of various compounds, which is a critical step in their metabolism. 3. **Lipid hydroxylation:** The enzyme is involved in the lipid hydroxylation of various compounds, which is essential for their metabolism and detoxification. **Clinical Significance:** The CYP3A5 enzyme plays a critical role in various clinical processes, including: 1. **Drug metabolism:** The enzyme is involved in the metabolism of many drugs, including immunosuppressants, antibiotics, and anticonvulsants. 2. **Cancer treatment:** CYP3A5 is involved in the metabolism of certain cancer therapies, including docetaxel and paclitaxel. 3. **Allergic reactions:** The enzyme is involved in the metabolism of allergens, which can lead to allergic reactions. 4. **Infectious diseases:** CYP3A5 is involved in the metabolism of certain antibiotics, which can lead to treatment failure. In conclusion, the CYP3A5 gene is a crucial component of the cytochrome P450 superfamily, playing a vital role in the metabolism and detoxification of various substances. Its expression in various tissues and its involvement in multiple physiological processes underscore its importance in human health and disease. Further research into the CYP3A5 enzyme is necessary to fully understand its role in human disease and to develop novel therapeutic strategies.

Genular Protein ID: 2684542022

Symbol: CP3A5_HUMAN

Name: CYPIIIA5

UniProtKB Accession Codes:

P20815 A4D289 B7Z5I7 Q53WY8 Q75MV0 Q9HB56

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 73 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 100 DrugCentral 1 EC 1 EMBL 11 Ensembl 3 ExpressionAtlas 1 GO 21 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 2 PRINTS 3 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 2 RefSeq 2 Rhea 40 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2732228

Title: Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine.

PubMed ID: 2732228

DOI: 10.1016/s0021-9258(18)81632-5

PubMed ID: 2802615

Title: Characterization of a cDNA encoding a new member of the glucocorticoid-responsive cytochromes P450 in human liver.

PubMed ID: 2802615

DOI: 10.1016/0003-9861(89)90449-9

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11266076

Title: Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene.

PubMed ID: 11266076

DOI: 10.1097/00008571-200103000-00002

PubMed ID: 8569713

Title: Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells.

PubMed ID: 8569713

PubMed ID: 7811260

Title: Sequence of the 5'-flanking region of CYP3A5: comparative analysis with CYP3A4 and CYP3A7.

PubMed ID: 7811260

DOI: 10.1006/bbrc.1994.2870

PubMed ID: 10681376

Title: Biosynthesis of all-trans-retinoic acid from all-trans-retinol: catalysis of all-trans-retinol oxidation by human P-450 cytochromes.

PubMed ID: 10681376

PubMed ID: 11093772

Title: Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.

PubMed ID: 11093772

DOI: 10.1124/mol.58.6.1341

PubMed ID: 11726664

Title: Intergenic mRNA molecules resulting from trans-splicing.

PubMed ID: 11726664

DOI: 10.1074/jbc.m109175200

PubMed ID: 12865317

Title: Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms.

PubMed ID: 12865317

DOI: 10.1210/en.2003-0192

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 8619878

Title: Detection of CYP3A5 allelic variant: a candidate for the polymorphic expression of the protein?

PubMed ID: 8619878

DOI: 10.1006/bbrc.1996.0618

PubMed ID: 11502729

Title: Genetic polymorphism of cytochrome P450 3A5 in Chinese.

PubMed ID: 11502729

PubMed ID: 12893984

Title: Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups.

PubMed ID: 12893984

DOI: 10.1097/00008571-200308000-00004

PubMed ID: 15469410

Title: Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population.

PubMed ID: 15469410

DOI: 10.1517/14622416.5.7.895

Sequence Information:

  • Length: 502
  • Mass: 57109
  • Checksum: D5A2302E2633E717
  • Sequence:
    • MDLIPNLAVE TWLLLAVSLV LLYLYGTRTH GLFKRLGIPG PTPLPLLGNV LSYRQGLWKF 
DTECYKKYGK MWGTYEGQLP VLAITDPDVI RTVLVKECYS VFTNRRSLGP VGFMKSAISL 
AEDEEWKRIR SLLSPTFTSG KLKEMFPIIA QYGDVLVRNL RREAEKGKPV TLKDIFGAYS 
MDVITGTSFG VNIDSLNNPQ DPFVESTKKF LKFGFLDPLF LSIILFPFLT PVFEALNVSL 
FPKDTINFLS KSVNRMKKSR LNDKQKHRLD FLQLMIDSQN SKETESHKAL SDLELAAQSI 
IFIFAGYETT SSVLSFTLYE LATHPDVQQK LQKEIDAVLP NKAPPTYDAV VQMEYLDMVV 
NETLRLFPVA IRLERTCKKD VEINGVFIPK GSMVVIPTYA LHHDPKYWTE PEEFRPERFS 
KKKDSIDPYI YTPFGTGPRN CIGMRFALMN MKLALIRVLQ NFSFKPCKET QIPLKLDTQG 
LLQPEKPIVL KVDSRDGTLS GE

Genular Protein ID: 369579349

Symbol: B7Z3P6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z3P6

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 10 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 4 Gene3D 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 3 PROSITE 1 PeptideAtlas 1 Pfam 1 RefSeq 1 Rhea 3 RuleBase 2 SAM 1 SUPFAM 1

Sequence Information:

  • Length: 492
  • Mass: 56070
  • Checksum: 6EBD4EC8756815C9
  • Sequence:
    • MQLLMLELLL LFIVYGTRTH GLFKRLGIPG PTPLPLLGNV LSYRQGLWKF DTECYKKYGK 
MWGTYEGQLP VLAITDPDVI RTVLVKECYS VFTNRRSLGP VGFMKSAISL AEDEEWKRIR 
SLLSPTFTSG KLKEMFPIIA QYGDVLVRNL RREAEKGKPV TLKDIFGAYS MDVITGTSFG 
VNIDSLNNPQ DPFVESTKKF LKFGFLDPLF LSIILFPFLT PVFEALNVSL FPKDTINFLS 
KSVNRMKKSR LNDKQKHRLD FLQLMIDSQN SKETESHKAL SDLELAAQSI IFIFAGYETT 
SSVLSFTLYE LATHPDVQQK LQKEIDAVLP NKAPPTYDAV VQMEYLDMVV NETLRLFPVA 
IRLERTCKKD VEINGVFIPK GSMVVIPTYA LHHDPKYWTE PEEFRPERFS KKKDSIDPYV 
YTPFGTGPRN CIGMRFALMN MKLALIRVLQ NFSFKPCKET QIPLKLDTQG LLQPEKPIVL 
KVDSRDGTLS GE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.