Details for: CYP3A5

Gene ID: 1577

Symbol: CYP3A5

Ensembl ID: ENSG00000106258

Description: cytochrome P450 family 3 subfamily A member 5

Associated with

Other Information

Genular Protein ID: 2684542022

Symbol: CP3A5_HUMAN

Name: CYPIIIA5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2732228

Title: Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine.

PubMed ID: 2732228

DOI: 10.1016/s0021-9258(18)81632-5

PubMed ID: 2802615

Title: Characterization of a cDNA encoding a new member of the glucocorticoid-responsive cytochromes P450 in human liver.

PubMed ID: 2802615

DOI: 10.1016/0003-9861(89)90449-9

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11266076

Title: Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene.

PubMed ID: 11266076

DOI: 10.1097/00008571-200103000-00002

PubMed ID: 8569713

Title: Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells.

PubMed ID: 8569713

PubMed ID: 7811260

Title: Sequence of the 5'-flanking region of CYP3A5: comparative analysis with CYP3A4 and CYP3A7.

PubMed ID: 7811260

DOI: 10.1006/bbrc.1994.2870

PubMed ID: 10681376

Title: Biosynthesis of all-trans-retinoic acid from all-trans-retinol: catalysis of all-trans-retinol oxidation by human P-450 cytochromes.

PubMed ID: 10681376

PubMed ID: 11093772

Title: Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.

PubMed ID: 11093772

DOI: 10.1124/mol.58.6.1341

PubMed ID: 11726664

Title: Intergenic mRNA molecules resulting from trans-splicing.

PubMed ID: 11726664

DOI: 10.1074/jbc.m109175200

PubMed ID: 12865317

Title: Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms.

PubMed ID: 12865317

DOI: 10.1210/en.2003-0192

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 8619878

Title: Detection of CYP3A5 allelic variant: a candidate for the polymorphic expression of the protein?

PubMed ID: 8619878

DOI: 10.1006/bbrc.1996.0618

PubMed ID: 11502729

Title: Genetic polymorphism of cytochrome P450 3A5 in Chinese.

PubMed ID: 11502729

PubMed ID: 12893984

Title: Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups.

PubMed ID: 12893984

DOI: 10.1097/00008571-200308000-00004

PubMed ID: 15469410

Title: Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population.

PubMed ID: 15469410

DOI: 10.1517/14622416.5.7.895

Sequence Information:

  • Length: 502
  • Mass: 57109
  • Checksum: D5A2302E2633E717
  • Sequence:
  • MDLIPNLAVE TWLLLAVSLV LLYLYGTRTH GLFKRLGIPG PTPLPLLGNV LSYRQGLWKF 
    DTECYKKYGK MWGTYEGQLP VLAITDPDVI RTVLVKECYS VFTNRRSLGP VGFMKSAISL 
    AEDEEWKRIR SLLSPTFTSG KLKEMFPIIA QYGDVLVRNL RREAEKGKPV TLKDIFGAYS 
    MDVITGTSFG VNIDSLNNPQ DPFVESTKKF LKFGFLDPLF LSIILFPFLT PVFEALNVSL 
    FPKDTINFLS KSVNRMKKSR LNDKQKHRLD FLQLMIDSQN SKETESHKAL SDLELAAQSI 
    IFIFAGYETT SSVLSFTLYE LATHPDVQQK LQKEIDAVLP NKAPPTYDAV VQMEYLDMVV 
    NETLRLFPVA IRLERTCKKD VEINGVFIPK GSMVVIPTYA LHHDPKYWTE PEEFRPERFS 
    KKKDSIDPYI YTPFGTGPRN CIGMRFALMN MKLALIRVLQ NFSFKPCKET QIPLKLDTQG 
    LLQPEKPIVL KVDSRDGTLS GE

Genular Protein ID: 369579349

Symbol: B7Z3P6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 492
  • Mass: 56070
  • Checksum: 6EBD4EC8756815C9
  • Sequence:
  • MQLLMLELLL LFIVYGTRTH GLFKRLGIPG PTPLPLLGNV LSYRQGLWKF DTECYKKYGK 
    MWGTYEGQLP VLAITDPDVI RTVLVKECYS VFTNRRSLGP VGFMKSAISL AEDEEWKRIR 
    SLLSPTFTSG KLKEMFPIIA QYGDVLVRNL RREAEKGKPV TLKDIFGAYS MDVITGTSFG 
    VNIDSLNNPQ DPFVESTKKF LKFGFLDPLF LSIILFPFLT PVFEALNVSL FPKDTINFLS 
    KSVNRMKKSR LNDKQKHRLD FLQLMIDSQN SKETESHKAL SDLELAAQSI IFIFAGYETT 
    SSVLSFTLYE LATHPDVQQK LQKEIDAVLP NKAPPTYDAV VQMEYLDMVV NETLRLFPVA 
    IRLERTCKKD VEINGVFIPK GSMVVIPTYA LHHDPKYWTE PEEFRPERFS KKKDSIDPYV 
    YTPFGTGPRN CIGMRFALMN MKLALIRVLQ NFSFKPCKET QIPLKLDTQG LLQPEKPIVL 
    KVDSRDGTLS GE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.