Details for: ADSL

Gene ID: 158

Symbol: ADSL

Ensembl ID: ENSG00000239900

Description: adenylosuccinate lyase

Associated with

Other Information

Genular Protein ID: 2820138176

Symbol: PUR8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8404037

Title: Mapping of the human adenylosuccinate lyase (ADSL) gene to chromosome 22q13.1-->q13.2.

PubMed ID: 8404037

DOI: 10.1159/000133575

PubMed ID: 10888601

Title: Human adenylosuccinate lyase (ADSL), cloning and characterization of full-length cDNA and its isoform, gene structure and molecular basis for ADSL deficiency in six patients.

PubMed ID: 10888601

DOI: 10.1093/hmg/9.10.1501

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1302001

Title: A mutation in adenylosuccinate lyase associated with mental retardation and autistic features.

PubMed ID: 1302001

DOI: 10.1038/ng0492-59

PubMed ID: 16973378

Title: Expression, purification, and characterization of stable, recombinant human adenylosuccinate lyase.

PubMed ID: 16973378

DOI: 10.1016/j.pep.2006.07.023

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 22812634

Title: Structural and biochemical characterization of human adenylosuccinate lyase (ADSL) and the R303C ADSL deficiency-associated mutation.

PubMed ID: 22812634

DOI: 10.1021/bi300796y

PubMed ID: 9266401

Title: Adenylosuccinase deficiency presenting with epilepsy in early infancy.

PubMed ID: 9266401

DOI: 10.1023/a:1005323512982

PubMed ID: 9545543

Title: Identification of new mutations in the adenylosuccinate lyase gene associated with impaired enzyme activity in lymphocytes and red blood cells.

PubMed ID: 9545543

DOI: 10.1016/s0925-4439(97)00086-0

PubMed ID: 10090474

Title: Mutation analysis in adenylosuccinate lyase deficiency: eight novel mutations in the re-evaluated full ADSL coding sequence.

PubMed ID: 10090474

DOI: 10.1002/(sici)1098-1004(1999)13:3<197::aid-humu3>3.0.co;2-d

PubMed ID: 10958654

Title: Clinical, biochemical and molecular genetic correlations in adenylosuccinate lyase deficiency.

PubMed ID: 10958654

DOI: 10.1093/hmg/9.14.2159

PubMed ID: 12016589

Title: Mutation of a nuclear respiratory factor 2 binding site in the 5' untranslated region of the ADSL gene in three patients with adenylosuccinate lyase deficiency.

PubMed ID: 12016589

DOI: 10.1086/341036

PubMed ID: 12070256

Title: Towards a suggestive facial dysmorphism in adenylosuccinate lyase deficiency?

PubMed ID: 12070256

DOI: 10.1136/jmg.39.6.440

PubMed ID: 12368987

Title: Screening for adenylosuccinate lyase deficiency: clinical, biochemical and molecular findings in four patients.

PubMed ID: 12368987

DOI: 10.1055/s-2002-34493

PubMed ID: 12833398

Title: Intrafamilial variability in the phenotypic expression of adenylosuccinate lyase deficiency: a report on three patients.

PubMed ID: 12833398

DOI: 10.1002/ajmg.a.20176

PubMed ID: 16839792

Title: Adenylosuccinate lyase deficiency.

PubMed ID: 16839792

DOI: 10.1016/j.ymgme.2006.04.018

PubMed ID: 19405474

Title: Biochemical and biophysical analysis of five disease-associated human adenylosuccinate lyase mutants.

PubMed ID: 19405474

DOI: 10.1021/bi802321m

Sequence Information:

  • Length: 484
  • Mass: 54889
  • Checksum: 7AA3A0A2C681FD94
  • Sequence:
  • MAAGGDHGSP DSYRSPLASR YASPEMCFVF SDRYKFRTWR QLWLWLAEAE QTLGLPITDE 
    QIQEMKSNLE NIDFKMAAEE EKRLRHDVMA HVHTFGHCCP KAAGIIHLGA TSCYVGDNTD 
    LIILRNALDL LLPKLARVIS RLADFAKERA SLPTLGFTHF QPAQLTTVGK RCCLWIQDLC 
    MDLQNLKRVR DDLRFRGVKG TTGTQASFLQ LFEGDDHKVE QLDKMVTEKA GFKRAFIITG 
    QTYTRKVDIE VLSVLASLGA SVHKICTDIR LLANLKEMEE PFEKQQIGSS AMPYKRNPMR 
    SERCCSLARH LMTLVMDPLQ TASVQWFERT LDDSANRRIC LAEAFLTADT ILNTLQNISE 
    GLVVYPKVIE RRIRQELPFM ATENIIMAMV KAGGSRQDCH EKIRVLSQQA ASVVKQEGGD 
    NDLIERIQVD AYFSPIHSQL DHLLDPSSFT GRASQQVQRF LEEEVYPLLK PYESVMKVKA 
    ELCL

Genular Protein ID: 1253245662

Symbol: X5D7W4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 24722188

Title: Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

PubMed ID: 24722188

Sequence Information:

  • Length: 46
  • Mass: 5193
  • Checksum: 66ACB1E1AB65000B
  • Sequence:
  • MAAGGDHGSP DSYRSPLASR YASPEMCFVF SDRHWVCLSQ MNKSRR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.