Genular: Defining Cellular Identity and Function

Details for: Ide

Gene ID: 15925

Symbol: Ide

Ensembl ID: ENSMUSG00000056999

Description: insulin degrading enzyme

Associated with

Deubiquitination
(R-MMU-5688426)
Metabolism of proteins
(R-MMU-392499)
Peroxisomal protein import
(R-MMU-9033241)
Post-translational protein modification
(R-MMU-597592)
Protein localization
(R-MMU-9609507)
Signaling by insulin receptor
(R-MMU-74752)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signal transduction
(R-MMU-162582)
Ub-specific processing proteases
(R-MMU-5689880)
Amyloid-beta binding
(GO:0001540)
Amyloid-beta clearance
(GO:0097242)
Amyloid-beta clearance by cellular catabolic process
(GO:0150094)
Amyloid-beta metabolic process
(GO:0050435)
Antigen processing and presentation of endogenous peptide antigen via mhc class i
(GO:0019885)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Basolateral plasma membrane
(GO:0016323)
Beta-endorphin binding
(GO:0031626)
Bradykinin catabolic process
(GO:0010815)
Catalytic activity
(GO:0003824)
Cell surface
(GO:0009986)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Cytosolic proteasome complex
(GO:0031597)
Endopeptidase activity
(GO:0004175)
Endosome lumen
(GO:0031904)
External side of plasma membrane
(GO:0009897)
Extracellular exosome
(GO:0070062)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Hormone catabolic process
(GO:0042447)
Hydrolase activity
(GO:0016787)
Identical protein binding
(GO:0042802)
Insulin binding
(GO:0043559)
Insulin catabolic process
(GO:1901143)
Insulin metabolic process
(GO:1901142)
Insulin receptor recycling
(GO:0038020)
Membrane
(GO:0016020)
Metabolic process
(GO:0008152)
Metal ion binding
(GO:0046872)
Metalloendopeptidase activity
(GO:0004222)
Metallopeptidase activity
(GO:0008237)
Mitochondrion
(GO:0005739)
Negative regulation of proteolysis
(GO:0045861)
Nucleotide binding
(GO:0000166)
Peptidase activity
(GO:0008233)
Peptide binding
(GO:0042277)
Peptide catabolic process
(GO:0043171)
Peptide hormone binding
(GO:0017046)
Peroxisomal matrix
(GO:0005782)
Peroxisome
(GO:0005777)
Plasma membrane
(GO:0005886)
Positive regulation of protein binding
(GO:0032092)
Protein-containing complex binding
(GO:0044877)
Protein catabolic process
(GO:0030163)
Protein homodimerization activity
(GO:0042803)
Proteolysis
(GO:0006508)
Proteolysis involved in protein catabolic process
(GO:0051603)
Regulation of aerobic respiration
(GO:1903715)
Response to oxidative stress
(GO:0006979)
Ubiquitin-dependent protein binding
(GO:0140036)
Ubiquitin recycling
(GO:0010992)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Q8CGB9_MOUSE

Genular Protein ID: 2011180883

Symbol: Q8CGB9_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8CGB9 F6RPJ9

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 1019
Mass: 117695
Checksum: 5DBC6C1C7E320054
Sequence:

MRNGLVWLLH PALPGTLRSI LGARPPPAKR LCGFPKQTYS TMSNPAIQRI EDQIVKSPED 
KREYRGLELA NGIKVLLISD PTTDKSSAAL DVHIGSLSDP PNIPGLSHFC EHMLFLGTKK 
YPKENEYSQF LSEHAGSSNA FTSGEHTNYY FDVSHEHLEG ALDRFAQFFL CPLFDASCKD 
REVNAVDSEH EKNVMNDAWR LFQLEKATGN PKHPFSKFGT GNKYTLETRP NQEGIDVREE 
LLKFHSTYYS SNLMAICVLG RESLDDLTNL VVKLFSEVEN KNVPLPEFPE HPFQEEHLRQ 
LYKIVPIKDI RNLYVTFPIP DLQQYYKSNP GHYLGHLIGH EGPGSLLSEL KSKGWVNTLV 
GGQKEGARGF MFFIINVDLT EEGLLHVEDI ILHMFQYIQK LRAEGPQEWV FQECKDLNAV 
AFRFKDKERP RGYTSKIAGK LHYYPLNGVL TAEYLLEEFR PDLIDMVLDK LRPENVRVAI 
VSKSFEGKTD RTEQWYGTQY KQEAIPEDII QKWQNADLNG KFKLPTKNEF IPTNFEILSL 
EKDATPYPAL IKDTAMSKLW FKQDDKFFLP KACLNFEFFS PFAYVDPLHC NMAYLYLELL 
KDSLNEYAYA AELAGLSYDL QNTIYGMYLS VKGYNDKQPI LLKKITEKMA TFEIDKKRFE 
IIKEAYMRSL NNFRAEQPHQ HAMYYLRLLM TEVAWTKDEL KEALDDVTLP RLKAFIPQLL 
SRLHIEALLH GNITKQAALG VMQMVEDTLI EHAHTKPLLP SQLVRYREVQ LPDRGWFVYQ 
QRNEVHNNCG IEIYYQTDMQ STSENMFLEL FCQIISEPCF NTLRTKEQLG YIVFSGPRRA 
NGIQGLRFII QSEKPPHYLE SRVEAFLITM EKAIEDMTEE AFQKHIQALA IRRLDKPKKL 
SAECAKYWGE IISQQYNYDR DNIEVAYLKT LTKDDIIRFY QEMLAVDAPR RHKVSVHVLA 
REMDSCPVVG EFPSQNDINL SEAPPLPQPE VIHNMTEFKR GLPLFPLVKP HINFMAAKL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ide

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Database document:

PubMed ID: 15489334

PubMed ID: 19468303

PubMed ID: 21183079

PubMed ID: 23806337