Genular: Defining Cellular Identity and Function

Details for: Ier3

Gene ID: 15937

Symbol: Ier3

Ensembl ID: ENSMUSG00000003541

Description: immediate early response 3

Associated with

Intracellular signaling by second messengers
(R-MMU-9006925)
Negative regulation of the pi3k/akt network
(R-MMU-199418)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-MMU-6811558)
Pip3 activates akt signaling
(R-MMU-1257604)
Signal transduction
(R-MMU-162582)
Dna damage response
(GO:0006974)
Glycolytic process
(GO:0006096)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
Membrane
(GO:0016020)
Mitotic g2 dna damage checkpoint signaling
(GO:0007095)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of glycolytic process
(GO:0045820)
Negative regulation of inflammatory response
(GO:0050728)
Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
(GO:1901029)
Negative regulation of systemic arterial blood pressure
(GO:0003085)
Nucleus
(GO:0005634)
Positive regulation of protein catabolic process
(GO:0045732)
Protein binding
(GO:0005515)
Regulation of dna repair
(GO:0006282)
Regulation of nucleocytoplasmic transport
(GO:0046822)
Regulation of reactive oxygen species metabolic process
(GO:2000377)
Response to protozoan
(GO:0001562)

Other Information

Proteins

Radiation-inducible immediate-early gene IEX-1

Genular Protein ID: 2187848169

Symbol: IEX1_MOUSE

Name: Radiation-inducible immediate-early gene IEX-1

UniProtKB Accession Codes:

P46694 Q4FJY1 Q91VZ5

Database IDs:

Citations:

PubMed ID: 8437864

Title: Genomic structure, cDNA sequence, and expression of gly96, a growth factor-inducible immediate-early gene encoding a short-lived glycosylated protein.

PubMed ID: 8437864

PubMed ID: 14644419

Title: Regulation of flotillin-1 in the establishment of NIH-3T3 cell-cell interactions.

PubMed ID: 14644419

DOI: 10.1016/s0014-5793(03)01239-0

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22565310

Title: Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis.

PubMed ID: 22565310

DOI: 10.1172/jci60144

Sequence Information:

Length: 160
Mass: 17655
Checksum: 0666DF96E751FCF4
Sequence:

MCHSRNHLHT MTGLRAPSPA PSTGPELRRG SGPEIFTFDP LPERAVVSTA RLNTSRGHRK 
RSRRVLYPRV VRRQLPTEEP NIAKRVLFLL FAIIFCQILM AEEGVSQPLA PEDATSAVTP 
EPISAPITAP PVLEPLNLTS ESSDYALDLK AFLQQHPAAF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ier3

Associated with

Other Information

Genomic structure, cDNA sequence, and expression of gly96, a growth factor-inducible immediate-early gene encoding a short-lived glycosylated protein. PubMed ID: 8437864

Regulation of flotillin-1 in the establishment of NIH-3T3 cell-cell interactions. PubMed ID: 14644419

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis. PubMed ID: 22565310