Details for: AP2A1

Gene ID: 160

Symbol: AP2A1

Ensembl ID: ENSG00000196961

Description: adaptor related protein complex 2 subunit alpha 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 128.2509
    Cell Significance Index: -32.5300
  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 120.2223
    Cell Significance Index: -18.7000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 75.4253
    Cell Significance Index: -35.6100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 72.8110
    Cell Significance Index: -29.5800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 66.7010
    Cell Significance Index: -34.3100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 31.0136
    Cell Significance Index: -29.6100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 24.9401
    Cell Significance Index: -30.7500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.2380
    Cell Significance Index: -30.1100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.8164
    Cell Significance Index: -34.7900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 8.2565
    Cell Significance Index: -18.0700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.0385
    Cell Significance Index: -24.6900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.8392
    Cell Significance Index: 49.1100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.6230
    Cell Significance Index: 189.1400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.5032
    Cell Significance Index: 244.4800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.1922
    Cell Significance Index: 163.7200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.1207
    Cell Significance Index: 15.2900
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 1.0822
    Cell Significance Index: 9.0900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.0487
    Cell Significance Index: 210.3600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.8597
    Cell Significance Index: 51.6100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.7319
    Cell Significance Index: 38.4300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7118
    Cell Significance Index: 141.2500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5496
    Cell Significance Index: 15.8400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4883
    Cell Significance Index: 337.7600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4573
    Cell Significance Index: 82.4400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4573
    Cell Significance Index: 164.0200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4440
    Cell Significance Index: 30.7100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4074
    Cell Significance Index: 50.1000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3993
    Cell Significance Index: 8.6500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3990
    Cell Significance Index: 217.8800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3340
    Cell Significance Index: 17.3500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2934
    Cell Significance Index: 264.9400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2219
    Cell Significance Index: 26.1700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2096
    Cell Significance Index: 16.0900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2011
    Cell Significance Index: 12.9800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1918
    Cell Significance Index: 84.8100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1863
    Cell Significance Index: 8.7600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1825
    Cell Significance Index: 23.3900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1787
    Cell Significance Index: 11.2700
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.1644
    Cell Significance Index: 2.1100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1624
    Cell Significance Index: 7.5700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1561
    Cell Significance Index: 15.4400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.1430
    Cell Significance Index: 4.1000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1166
    Cell Significance Index: 3.1300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1113
    Cell Significance Index: 3.1100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0683
    Cell Significance Index: 2.4000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0582
    Cell Significance Index: 11.0700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0430
    Cell Significance Index: 0.9000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0199
    Cell Significance Index: 37.5400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0112
    Cell Significance Index: 0.6900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0089
    Cell Significance Index: 16.3700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0043
    Cell Significance Index: 0.5600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0011
    Cell Significance Index: 1.6300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0029
    Cell Significance Index: -1.8200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0107
    Cell Significance Index: -14.5600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0112
    Cell Significance Index: -5.0700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0197
    Cell Significance Index: -3.3600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0281
    Cell Significance Index: -20.6200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0284
    Cell Significance Index: -0.6100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0305
    Cell Significance Index: -23.0700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0364
    Cell Significance Index: -0.6100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0395
    Cell Significance Index: -29.2900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0468
    Cell Significance Index: -4.7800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0555
    Cell Significance Index: -31.3000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0580
    Cell Significance Index: -4.3200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0629
    Cell Significance Index: -39.3100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0671
    Cell Significance Index: -1.1500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0676
    Cell Significance Index: -1.8400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1015
    Cell Significance Index: -29.2000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1169
    Cell Significance Index: -8.2700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1240
    Cell Significance Index: -8.3400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1291
    Cell Significance Index: -18.7700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1468
    Cell Significance Index: -3.8600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1776
    Cell Significance Index: -5.2200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1822
    Cell Significance Index: -38.3800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.1834
    Cell Significance Index: -3.3900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1962
    Cell Significance Index: -22.4800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2195
    Cell Significance Index: -12.3200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2307
    Cell Significance Index: -7.3900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2427
    Cell Significance Index: -2.2400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2487
    Cell Significance Index: -11.0000
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.2616
    Cell Significance Index: -3.6700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.2654
    Cell Significance Index: -5.1800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2910
    Cell Significance Index: -13.1900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2994
    Cell Significance Index: -8.0100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.3068
    Cell Significance Index: -3.8100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3098
    Cell Significance Index: -32.2600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3427
    Cell Significance Index: -9.7800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3525
    Cell Significance Index: -13.3500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3788
    Cell Significance Index: -30.0000
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.3851
    Cell Significance Index: -3.1400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4713
    Cell Significance Index: -11.7800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4837
    Cell Significance Index: -16.8100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.4939
    Cell Significance Index: -25.7300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.5472
    Cell Significance Index: -13.9800
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.5514
    Cell Significance Index: -4.2500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5692
    Cell Significance Index: -34.9000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.5737
    Cell Significance Index: -13.7600
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: -0.5859
    Cell Significance Index: -3.6300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.5960
    Cell Significance Index: -12.6500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.6091
    Cell Significance Index: -19.4000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **AP-2 Adaptor Complex**: AP2A1 is a subunit of the AP-2 adaptor complex, which is a multi-protein complex involved in the regulation of various cellular processes. 2. **Endocytosis**: AP2A1 is involved in receptor-mediated endocytosis, a process by which cells internalize receptors and cargo from the plasma membrane. 3. **Synaptic Plasticity**: AP2A1 plays a role in synaptic plasticity, the mechanism underlying learning and memory. 4. **Immune System**: AP2A1 is expressed in immune cells, where it regulates immune responses and interactions with pathogens. 5. **Neuronal System**: AP2A1 is also expressed in neurons, where it regulates neurotransmitter receptor internalization and synaptic transmission. **Pathways and Functions** 1. **Clathrin-Coated Endocytosis**: AP2A1 is involved in clathrin-coated endocytosis, the process by which cells internalize receptors and cargo from the plasma membrane. 2. **Signaling by Receptor Tyrosine Kinases**: AP2A1 interacts with receptor tyrosine kinases, regulating signaling pathways involved in cell growth, differentiation, and survival. 3. **Wnt Signaling**: AP2A1 is involved in Wnt signaling, a pathway regulating cell proliferation, differentiation, and survival. 4. **Infectious Disease**: AP2A1 plays a role in the regulation of viral infections, including HIV-1 replication and disease pathogenesis. 5. **Neurotransmitter Receptor Internalization**: AP2A1 regulates the internalization of neurotransmitter receptors, a process critical for synaptic plasticity and learning. **Clinical Significance** 1. **Infectious Diseases**: AP2A1 plays a role in the regulation of viral infections, including HIV-1, and its dysregulation may contribute to disease pathogenesis. 2. **Neurological Disorders**: AP2A1 is involved in synaptic plasticity and neurotransmitter receptor internalization, and its dysregulation may contribute to neurological disorders, such as Alzheimer's disease and Parkinson's disease. 3. **Immunological Disorders**: AP2A1 regulates immune responses and interactions with pathogens, and its dysregulation may contribute to immunological disorders, such as autoimmune diseases. 4. **Cancer**: AP2A1 is involved in cell growth, differentiation, and survival, and its dysregulation may contribute to cancer development and progression. 5. **Potential Therapeutics**: AP2A1 may serve as a target for therapeutic interventions in infectious diseases, neurological disorders, and immunological disorders. In conclusion, AP2A1 is a multifunctional gene involved in various cellular processes, including endocytosis, signaling, and cell migration. Its dysregulation may contribute to disease pathogenesis, and its potential as a therapeutic target makes it an important area of research.

Genular Protein ID: 628385147

Symbol: AP2A1_HUMAN

Name: AP-2 complex subunit alpha-1

UniProtKB Accession Codes:

O95782 Q96CI7 Q96PP6 Q96PP7 Q9H070

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 7 Ensembl 2 ExpressionAtlas 1 GO 27 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 14 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12036598

Title: Cloning, physical mapping and structural characterization of the human alpha(A)-adaptin gene.

PubMed ID: 12036598

DOI: 10.1016/s0378-1119(02)00504-8

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11532990

Title: The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis.

PubMed ID: 11532990

DOI: 10.1093/hmg/10.17.1807

PubMed ID: 12364336

Title: Rab11-FIP2, an adaptor protein connecting cellular components involved in internalization and recycling of epidermal growth factor receptors.

PubMed ID: 12364336

DOI: 10.1074/jbc.m206316200

PubMed ID: 14745134

Title: Adaptor protein complexes as the key regulators of protein sorting in the post-Golgi network.

PubMed ID: 14745134

DOI: 10.1247/csf.28.419

PubMed ID: 15473838

Title: Adaptors for clathrin coats: structure and function.

PubMed ID: 15473838

DOI: 10.1146/annurev.cellbio.20.010403.104543

PubMed ID: 16262731

Title: Effect of clathrin assembly lymphoid myeloid leukemia protein depletion on clathrin coat formation.

PubMed ID: 16262731

DOI: 10.1111/j.1600-0854.2005.00355.x

PubMed ID: 19033387

Title: The adaptor complex AP-2 regulates post-endocytic trafficking through the non-clathrin Arf6-dependent endocytic pathway.

PubMed ID: 19033387

DOI: 10.1242/jcs.033522

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22262466

Title: AP2 adaptor complex mediates bile salt export pump internalization and modulates its hepatocanalicular expression and transport function.

PubMed ID: 22262466

DOI: 10.1002/hep.25591

PubMed ID: 23676497

Title: Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease.

PubMed ID: 23676497

DOI: 10.1172/jci65401

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27022195

Title: Raftlin controls lipopolysaccharide-induced TLR4 internalization and TICAM-1 signaling in a cell type-specific manner.

PubMed ID: 27022195

DOI: 10.4049/jimmunol.1501734

PubMed ID: 29262337

Title: APache is an AP2-interacting protein involved in synaptic vesicle trafficking and neuronal development.

PubMed ID: 29262337

DOI: 10.1016/j.celrep.2017.11.073

Sequence Information:

  • Length: 977
  • Mass: 107546
  • Checksum: D9FB569E7EDDF6ED
  • Sequence:
    • MPAVSKGDGM RGLAVFISDI RNCKSKEAEI KRINKELANI RSKFKGDKAL DGYSKKKYVC 
KLLFIFLLGH DIDFGHMEAV NLLSSNKYTE KQIGYLFISV LVNSNSELIR LINNAIKNDL 
ASRNPTFMCL ALHCIANVGS REMGEAFAAD IPRILVAGDS MDSVKQSAAL CLLRLYKASP 
DLVPMGEWTA RVVHLLNDQH MGVVTAAVSL ITCLCKKNPD DFKTCVSLAV SRLSRIVSSA 
STDLQDYTYY FVPAPWLSVK LLRLLQCYPP PEDAAVKGRL VECLETVLNK AQEPPKSKKV 
QHSNAKNAIL FETISLIIHY DSEPNLLVRA CNQLGQFLQH RETNLRYLAL ESMCTLASSE 
FSHEAVKTHI DTVINALKTE RDVSVRQRAA DLLYAMCDRS NAKQIVSEML RYLETADYAI 
REEIVLKVAI LAEKYAVDYS WYVDTILNLI RIAGDYVSEE VWYRVLQIVT NRDDVQGYAA 
KTVFEALQAP ACHENMVKVG GYILGEFGNL IAGDPRSSPP VQFSLLHSKF HLCSVATRAL 
LLSTYIKFIN LFPETKATIQ GVLRAGSQLR NADVELQQRA VEYLTLSSVA STDVLATVLE 
EMPPFPERES SILAKLKRKK GPGAGSALDD GRRDPSSNDI NGGMEPTPST VSTPSPSADL 
LGLRAAPPPA APPASAGAGN LLVDVFDGPA AQPSLGPTPE EAFLSELEPP APESPMALLA 
DPAPAADPGP EDIGPPIPEA DELLNKFVCK NNGVLFENQL LQIGVKSEFR QNLGRMYLFY 
GNKTSVQFQN FSPTVVHPGD LQTQLAVQTK RVAAQVDGGA QVQQVLNIEC LRDFLTPPLL 
SVRFRYGGAP QALTLKLPVT INKFFQPTEM AAQDFFQRWK QLSLPQQEAQ KIFKANHPMD 
AEVTKAKLLG FGSALLDNVD PNPENFVGAG IIQTKALQVG CLLRLEPNAQ AQMYRLTLRT 
SKEPVSRHLC ELLAQQF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.