Details for: Ccn1

Gene ID: 16007

Symbol: Ccn1

Ensembl ID: ENSMUSG00000028195

Description: cellular communication network factor 1

Associated with

  • Metabolism of proteins
    (R-MMU-392499)
  • Post-translational protein modification
    (R-MMU-597592)
  • Post-translational protein phosphorylation
    (R-MMU-8957275)
  • Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
    (R-MMU-381426)
  • Apoptotic process
    (GO:0006915)
  • Apoptotic process involved in heart morphogenesis
    (GO:0003278)
  • Atrial septum morphogenesis
    (GO:0060413)
  • Atrioventricular valve morphogenesis
    (GO:0003181)
  • Cell-cell adhesion
    (GO:0098609)
  • Cell adhesion
    (GO:0007155)
  • Chemotaxis
    (GO:0006935)
  • Chondroblast differentiation
    (GO:0060591)
  • Chorio-allantoic fusion
    (GO:0060710)
  • Collagen-containing extracellular matrix
    (GO:0062023)
  • Cytosol
    (GO:0005829)
  • Extracellular matrix binding
    (GO:0050840)
  • Extracellular matrix organization
    (GO:0030198)
  • Extracellular region
    (GO:0005576)
  • Extracellular space
    (GO:0005615)
  • Growth factor binding
    (GO:0019838)
  • Heparin binding
    (GO:0008201)
  • Integrin binding
    (GO:0005178)
  • Intussusceptive angiogenesis
    (GO:0002041)
  • Labyrinthine layer blood vessel development
    (GO:0060716)
  • Membrane
    (GO:0016020)
  • Negative regulation of apoptotic process
    (GO:0043066)
  • Osteoblast differentiation
    (GO:0001649)
  • Positive regulation of apoptotic process
    (GO:0043065)
  • Positive regulation of bmp signaling pathway
    (GO:0030513)
  • Positive regulation of bone mineralization
    (GO:0030501)
  • Positive regulation of cartilage development
    (GO:0061036)
  • Positive regulation of cell-substrate adhesion
    (GO:0010811)
  • Positive regulation of cell differentiation
    (GO:0045597)
  • Positive regulation of cell migration
    (GO:0030335)
  • Positive regulation of ceramide biosynthetic process
    (GO:2000304)
  • Positive regulation of chemokine (c-x-c motif) ligand 2 production
    (GO:2000343)
  • Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
    (GO:0043280)
  • Positive regulation of interleukin-1 beta production
    (GO:0032731)
  • Positive regulation of interleukin-6 production
    (GO:0032755)
  • Positive regulation of interleukin-17 production
    (GO:0032740)
  • Positive regulation of osteoblast differentiation
    (GO:0045669)
  • Positive regulation of osteoblast proliferation
    (GO:0033690)
  • Positive regulation of phospholipase activity
    (GO:0010518)
  • Positive regulation of protein kinase activity
    (GO:0045860)
  • Positive regulation of protein phosphorylation
    (GO:0001934)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
    (GO:2000309)
  • Positive regulation of tumor necrosis factor production
    (GO:0032760)
  • Reactive oxygen species metabolic process
    (GO:0072593)
  • Regulation of erk1 and erk2 cascade
    (GO:0070372)
  • Signal transduction
    (GO:0007165)
  • Ventricular septum development
    (GO:0003281)
  • Wound healing, spreading of cells
    (GO:0044319)

Other Information

Genular Protein ID: 4002767399

Symbol: CCN1_MOUSE

Name: CCN family member 1

UniProtKB Accession Codes:

P18406

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 Ensembl 1 ExpressionAtlas 1 GO 45 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRO 1 PROSITE 7 PROSITE-ProRule 4 PaxDb 1 PeptideAtlas 1 Pfam 4 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 SMART 4 SMR 1 STRING 1 SUPFAM 3 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 2355916

Title: Expression of cyr61, a growth factor-inducible immediate-early gene.

PubMed ID: 2355916

DOI: 10.1128/mcb.10.7.3569-3577.1990

PubMed ID: 2062642

Title: Promoter function and structure of the growth factor-inducible immediate early gene cyr61.

PubMed ID: 2062642

DOI: 10.1093/nar/19.12.3261

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10821835

Title: Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin alpha 6beta 1 and cell surface heparan sulfate proteoglycans.

PubMed ID: 10821835

DOI: 10.1074/jbc.m003040200

Sequence Information:

  • Length: 379
  • Mass: 41709
  • Checksum: FA6B5014B56A8EE9
  • Sequence:
    • MSSSTFRTLA VAVTLLHLTR LALSTCPAAC HCPLEAPKCA PGVGLVRDGC GCCKVCAKQL 
NEDCSKTQPC DHTKGLECNF GASSTALKGI CRAQSEGRPC EYNSRIYQNG ESFQPNCKHQ 
CTCIDGAVGC IPLCPQELSL PNLGCPNPRL VKVSGQCCEE WVCDEDSIKD SLDDQDDLLG 
LDASEVELTR NNELIAIGKG SSLKRLPVFG TEPRVLFNPL HAHGQKCIVQ TTSWSQCSKS 
CGTGISTRVT NDNPECRLVK ETRICEVRPC GQPVYSSLKK GKKCSKTKKS PEPVRFTYAG 
CSSVKKYRPK YCGSCVDGRC CTPLQTRTVK MRFRCEDGEM FSKNVMMIQS CKCNYNCPHP 
NEASFRLYSL FNDIHKFRD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.