Details for: DAP

Gene ID: 1611

Symbol: DAP

Ensembl ID: ENSG00000112977

Description: death associated protein

Associated with

  • Activation of cysteine-type endopeptidase activity involved in apoptotic process
    (GO:0006919)
  • Apoptotic process
    (GO:0006915)
  • Apoptotic signaling pathway
    (GO:0097190)
  • Autophagy
    (GO:0006914)
  • Cellular response to amino acid starvation
    (GO:0034198)
  • Death domain binding
    (GO:0070513)
  • Negative regulation of autophagy
    (GO:0010507)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of nf-kappab transcription factor activity
    (GO:0032088)
  • Regulation of translation
    (GO:0006417)

Other Information

Genular Protein ID: 1419481593

Symbol: DAP1_HUMAN

Name: N/A

UniProtKB Accession Codes:

P51397 Q6FGC3 Q9BUC9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 10 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 2 SAM 1 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7828849

Title: Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death.

PubMed ID: 7828849

DOI: 10.1101/gad.9.1.15

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16602700

Title: Beyond linker histones and high mobility group proteins: global profiling of perchloric acid soluble proteins.

PubMed ID: 16602700

DOI: 10.1021/pr050415p

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20537536

Title: DAP1, a novel substrate of mTOR, negatively regulates autophagy.

PubMed ID: 20537536

DOI: 10.1016/j.cub.2010.04.041

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

Sequence Information:

  • Length: 102
  • Mass: 11165
  • Checksum: 52FBEFD23ABD182F
  • Sequence:
    • MSSPPEGKLE TKAGHPPAVK AGGMRIVQKH PHTGDTKEEK DKDDQEWESP SPPKPTVFIS 
GVIARGDKDF PPAAAQVAHQ KPHASMDKHP SPRTQHIQQP RK

Genular Protein ID: 3754185718

Symbol: B4DQ75_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DQ75

Database IDs:

ARBA 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 EPD 1 Ensembl 2 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 204
  • Mass: 23224
  • Checksum: 05A17C36622FF8A9
  • Sequence:
    • MSSPPEGKLE TKAGHPPAVK AGGMRIVQKH PHTGDTKEEK DKDDQEWESP RVTKISPRRL 
RRWLTRSRMP PWTSILPQEP STSSSHASEP GVHQPAPWPR LCCTWYFPDR ENQQFRPNPT 
LLGNLRQNQV LCPLPYISIF KTRNSSSPNL VYGESGWMSF EDHCAPRGAI SRICQDPRKI 
LALVLFQQSP DVLVYGLKNK KAHI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.