Details for: Igtp
Associated with
Other Information
Genular Protein ID: 2295265856
Symbol: IRGM3_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 22892676
Title: Comparative genomic analysis of eutherian interferon-gamma-inducible GTPases.
PubMed ID: 22892676
PubMed ID: 8702776
Title: Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma.
PubMed ID: 8702776
PubMed ID: 9099712
Title: The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding.
PubMed ID: 9099712
PubMed ID: 10639151
Title: Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP.
PubMed ID: 10639151
PubMed ID: 11500431
Title: Gamma interferon-induced inhibition of Toxoplasma gondii in astrocytes is mediated by IGTP.
PubMed ID: 11500431
PubMed ID: 12438372
Title: The function of gamma interferon-inducible GTP-binding protein IGTP in host resistance to Toxoplasma gondii is Stat1 dependent and requires expression in both hematopoietic and nonhematopoietic cellular compartments.
PubMed ID: 12438372
PubMed ID: 16940170
Title: Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages.
PubMed ID: 16940170
DOI: 10.1084/jem.20061318
PubMed ID: 18765738
Title: The gamma interferon (IFN-gamma)-inducible GTP-binding protein IGTP is necessary for toxoplasma vacuolar disruption and induces parasite egression in IFN-gamma-stimulated astrocytes.
PubMed ID: 18765738
DOI: 10.1128/iai.01288-07
PubMed ID: 21981022
Title: The immunity-related GTPase Irgm3 relieves endoplasmic reticulum stress response during coxsackievirus B3 infection via a PI3K/Akt dependent pathway.
PubMed ID: 21981022
PubMed ID: 25644000
Title: IRGM3 contributes to immunopathology and is required for differentiation of antigen-specific effector CD8+ T cells in experimental cerebral malaria.
PubMed ID: 25644000
DOI: 10.1128/iai.02701-14
PubMed ID: 23785284
Title: IRG and GBP host resistance factors target aberrant, 'non-self' vacuoles characterized by the missing of 'self' IRGM proteins.
PubMed ID: 23785284
PubMed ID: 36629440
Title: Differential requirement for IRGM proteins during Tuberculosis infection in mice.
PubMed ID: 36629440
DOI: 10.1128/iai.00510-22
Sequence Information:
- Length: 423
- Mass: 48494
- Checksum: 8FAA2254A6DF4574
- Sequence:
MDLVTKLPQN IWKTFTLFIN MANYLKRLIS PWSKSMTAGE SLYSSQNSSS PEVIEDIGKA VTEGNLQKVI GIVKDEIQSK SRYRVKIAVT GDSGNGMSSF INALRFIGHE EEDSAPTGVV RTTKKPACYS SDSHFPYVEL WDLPGLGATA QSVESYLEEM QISTFDLIII VASEQFSSNH VKLAITMQRM RKRFYVVWTK LDRDLSTSTF PEPQLLQSIQ RNIRENLQQA QVRDPPLFLI SCFSPSFHDF PELRNTLQKD IFSIRYRDPL EIISQVCDKC ISNKAFSLKE DQMLMKDLEA AVSSEDDTAN LERGLQTYQK LFGVDDGSLQ QVARSTGRLE MGSRALQFQD LIKMDRRLEL MMCFAVNKFL RLLESSWWYG LWNVVTRYFR HQRHKLVIEI VAENTKTSLR KALKDSVLPP EIH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.