Details for: Il17ra

Gene ID: 16172

Symbol: Il17ra

Ensembl ID: ENSMUSG00000002897

Description: interleukin 17 receptor A

Associated with

Other Information

Genular Protein ID: 708469688

Symbol: I17RA_MOUSE

Name: Interleukin-17 receptor A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8777726

Title: Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor.

PubMed ID: 8777726

DOI: 10.1016/1074-7613(95)90070-5

PubMed ID: 17911633

Title: Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F.

PubMed ID: 17911633

DOI: 10.4049/jimmunol.179.8.5462

PubMed ID: 18157131

Title: Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice.

PubMed ID: 18157131

DOI: 10.1038/ni1552

PubMed ID: 19144317

Title: Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses.

PubMed ID: 19144317

DOI: 10.1016/j.immuni.2008.11.009

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20364087

Title: IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice.

PubMed ID: 20364087

DOI: 10.1172/jci40891

PubMed ID: 20554964

Title: IL-17RC is required for immune signaling via an extended SEF/IL-17R signaling domain in the cytoplasmic tail.

PubMed ID: 20554964

DOI: 10.4049/jimmunol.0903739

PubMed ID: 21982598

Title: Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E.

PubMed ID: 21982598

DOI: 10.1016/j.immuni.2011.09.010

PubMed ID: 21993849

Title: IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens.

PubMed ID: 21993849

DOI: 10.1038/ni.2155

PubMed ID: 21993848

Title: IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.

PubMed ID: 21993848

DOI: 10.1038/ni.2156

PubMed ID: 27923703

Title: IL-17 Receptor Signaling in the Lung Epithelium Is Required for Mucosal Chemokine Gradients and Pulmonary Host Defense against K. pneumoniae.

PubMed ID: 27923703

DOI: 10.1016/j.chom.2016.10.003

PubMed ID: 26735852

Title: IL-17A Promotes Pulmonary B-1a Cell Differentiation via Induction of Blimp-1 Expression during Influenza Virus Infection.

PubMed ID: 26735852

DOI: 10.1371/journal.ppat.1005367

PubMed ID: 28813677

Title: The IL-17F/IL-17RC Axis Promotes Respiratory Allergy in the Proximal Airways.

PubMed ID: 28813677

DOI: 10.1016/j.celrep.2017.07.063

PubMed ID: 27795421

Title: Interleukin-17A Promotes CD8+ T Cell Cytotoxicity To Facilitate West Nile Virus Clearance.

PubMed ID: 27795421

DOI: 10.1128/jvi.01529-16

PubMed ID: 33723527

Title: Title: ORF8 contributes to cytokine storm during SARS-CoV-2 infection by activating IL-17 pathway.

PubMed ID: 33723527

DOI: 10.1016/j.isci.2021.102293

Sequence Information:

  • Length: 864
  • Mass: 97808
  • Checksum: 343FD51AA687DA31
  • Sequence:
  • MAIRRCWPRV VPGPALGWLL LLLNVLAPGR ASPRLLDFPA PVCAQEGLSC RVKNSTCLDD 
    SWIHPKNLTP SSPKNIYINL SVSSTQHGEL VPVLHVEWTL QTDASILYLE GAELSVLQLN 
    TNERLCVKFQ FLSMLQHHRK RWRFSFSHFV VDPGQEYEVT VHHLPKPIPD GDPNHKSKII 
    FVPDCEDSKM KMTTSCVSSG SLWDPNITVE TLDTQHLRVD FTLWNESTPY QVLLESFSDS 
    ENHSCFDVVK QIFAPRQEEF HQRANVTFTL SKFHWCCHHH VQVQPFFSSC LNDCLRHAVT 
    VPCPVISNTT VPKPVADYIP LWVYGLITLI AILLVGSVIV LIICMTWRLS GADQEKHGDD 
    SKINGILPVA DLTPPPLRPR KVWIVYSADH PLYVEVVLKF AQFLITACGT EVALDLLEEQ 
    VISEVGVMTW VSRQKQEMVE SNSKIIILCS RGTQAKWKAI LGWAEPAVQL RCDHWKPAGD 
    LFTAAMNMIL PDFKRPACFG TYVVCYFSGI CSERDVPDLF NITSRYPLMD RFEEVYFRIQ 
    DLEMFEPGRM HHVRELTGDN YLQSPSGRQL KEAVLRFQEW QTQCPDWFER ENLCLADGQD 
    LPSLDEEVFE DPLLPPGGGI VKQQPLVREL PSDGCLVVDV CVSEEESRMA KLDPQLWPQR 
    ELVAHTLQSM VLPAEQVPAA HVVEPLHLPD GSGAAAQLPM TEDSEACPLL GVQRNSILCL 
    PVDSDDLPLC STPMMSPDHL QGDAREQLES LMLSVLQQSL SGQPLESWPR PEVVLEGCTP 
    SEEEQRQSVQ SDQGYISRSS PQPPEWLTEE EELELGEPVE SLSPEELRSL RKLQRQLFFW 
    ELEKNPGWNS LEPRRPTPEE QNPS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.