Genular: Defining Cellular Identity and Function

Details for: Il18rap

Gene ID: 16174

Symbol: Il18rap

Ensembl ID: ENSMUSG00000026068

Description: interleukin 18 receptor accessory protein

Associated with

Cytokine signaling in immune system
(R-MMU-1280215)
Immune system
(R-MMU-168256)
Interleukin-1 family signaling
(R-MMU-446652)
Interleukin-18 signaling
(R-MMU-9012546)
Signaling by interleukins
(R-MMU-449147)
Cell population proliferation
(GO:0008283)
Cellular response to interleukin-18
(GO:0071351)
Coreceptor activity
(GO:0015026)
Hydrolase activity
(GO:0016787)
Inflammatory response
(GO:0006954)
Interleukin-1 receptor activity
(GO:0004908)
Interleukin-6 production
(GO:0032635)
Interleukin-18 receptor activity
(GO:0042008)
Interleukin-18 receptor complex
(GO:0045092)
Interleukin-18-mediated signaling pathway
(GO:0035655)
Membrane
(GO:0016020)
Nad+ nucleotidase, cyclic adp-ribose generating
(GO:0061809)
Nadp+ nucleosidase activity
(GO:0050135)
Neutrophil activation
(GO:0042119)
Plasma membrane
(GO:0005886)
Positive regulation of natural killer cell mediated cytotoxicity
(GO:0045954)
Positive regulation of nf-kappab transcription factor activity
(GO:0051092)
Signal transduction
(GO:0007165)
T-helper 1 cell cytokine production
(GO:0035744)
Type ii interferon production
(GO:0032609)

Other Information

Proteins

Interleukin-18 receptor accessory protein
Q3TTU1_MOUSE

Genular Protein ID: 938145432

Symbol: I18RA_MOUSE

Name: Interleukin-18 receptor accessory protein

UniProtKB Accession Codes:

Q9Z2B1

Database IDs:

Citations:

PubMed ID: 9792649

Title: Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling.

PubMed ID: 9792649

DOI: 10.1074/jbc.273.45.29445

PubMed ID: 11046021

Title: IL-18 receptors, their role in ligand binding and function: anti-IL-1RAcPL antibody, a potent antagonist of IL-18.

PubMed ID: 11046021

DOI: 10.4049/jimmunol.165.9.4950

PubMed ID: 15843532

Title: Accessory protein-like is essential for IL-18-mediated signaling.

PubMed ID: 15843532

DOI: 10.4049/jimmunol.174.9.5351

Sequence Information:

Length: 614
Mass: 70094
Checksum: B71D005E4FA99BA1
Sequence:

MLCLGWVFLW FVAGEKTTGF NHSACATKKL LWTYSARGAE NFVLFCDLQE LQEQKFSHAS 
QLSPTQSPAH KPCSGSQKDL SDVQWYMQPR SGSPLEEISR NSPHMQSEGM LHILAPQTNS 
IWSYICRPRI RSPQDMACCI KTVLEVKPQR NVSCGNTAQD EQVLLLGSTG SIHCPSLSCQ 
SDVQSPEMTW YKDGRLLPEH KKNPIEMADI YVFNQGLYVC DYTQSDNVSS WTVRAVVKVR 
TIGKDINVKP EILDPITDTL DVELGKPLTL PCRVQFGFQR LSKPVIKWYV KESTQEWEMS 
VFEEKRIQST FKNEVIERTI FLREVTQRDL SRKFVCFAQN SIGNTTRTIR LRKKEEVVFV 
YILLGTALML VGVLVAAAFL YWYWIEVVLL CRTYKNKDET LGDKKEFDAF VSYSNWSSPE 
TDAVGSLSEE HLALNLFPEV LEDTYGYRLC LLDRDVTPGG VYADDIVSII KKSRRGIFIL 
SPSYLNGPRV FELQAAVNLA LVDQTLKLIL IKFCSFQEPE SLPYLVKKAL RVLPTVTWKG 
LKSVHASSRF WTQIRYHMPV KNSNRFMFNG LRIFLKGFSP EKDLVTQKPL EGMPKSGNDH 
GAQNLLLYSD QKRC

Genular Protein ID: 1981684853

Symbol: Q3TTU1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3TTU1

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 59
Mass: 6784
Checksum: 1497C6F8DABEE3F1
Sequence:

YHMPVKNSNR FMFNGLRIFL KGFSPEKDLV TQKPLEGMPK SGNDHGAQNL LLYSDQNRC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Il18rap

Associated with

Other Information

Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling. PubMed ID: 9792649

IL-18 receptors, their role in ligand binding and function: anti-IL-1RAcPL antibody, a potent antagonist of IL-18. PubMed ID: 11046021

Accessory protein-like is essential for IL-18-mediated signaling. PubMed ID: 15843532

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073