Genular: Defining Cellular Identity and Function

Details for: Il1r2

Gene ID: 16178

Symbol: Il1r2

Ensembl ID: ENSMUSG00000026073

Description: interleukin 1 receptor, type II

Associated with

Cytokine signaling in immune system
(R-MMU-1280215)
Immune system
(R-MMU-168256)
Interleukin-1 family signaling
(R-MMU-446652)
Interleukin-1 signaling
(R-MMU-9020702)
Signaling by interleukins
(R-MMU-449147)
Cytoplasm
(GO:0005737)
Extracellular region
(GO:0005576)
Interleukin-1 binding
(GO:0019966)
Interleukin-1 receptor activity
(GO:0004908)
Interleukin-1, type ii, blocking receptor activity
(GO:0004910)
Membrane
(GO:0016020)
Negative regulation of cytokine production involved in inflammatory response
(GO:1900016)
Negative regulation of interleukin-1 alpha production
(GO:0032690)
Negative regulation of interleukin-1-mediated signaling pathway
(GO:2000660)
Negative regulation of protein processing
(GO:0010955)
Plasma membrane
(GO:0005886)
Protein processing
(GO:0016485)

Other Information

Proteins

Interleukin-1 receptor type 2

Genular Protein ID: 2869644786

Symbol: IL1R2_MOUSE

Name: Interleukin-1 receptor type 2

UniProtKB Accession Codes:

P27931

Database IDs:

Citations:

PubMed ID: 1833184

Title: A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.

PubMed ID: 1833184

DOI: 10.1002/j.1460-2075.1991.tb07831.x

PubMed ID: 8332913

Title: Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4.

PubMed ID: 8332913

DOI: 10.1126/science.8332913

PubMed ID: 9662436

Title: Interleukin-1 receptor accessory protein interacts with the type II interleukin-1 receptor.

PubMed ID: 9662436

DOI: 10.1016/s0014-5793(98)00467-0

PubMed ID: 16944957

Title: Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

PubMed ID: 16944957

DOI: 10.1021/pr060186m

PubMed ID: 15986350

Title: Soluble interleukin-1 receptor accessory protein ameliorates collagen-induced arthritis by a different mode of action from that of interleukin-1 receptor antagonist.

PubMed ID: 15986350

DOI: 10.1002/art.21108

Sequence Information:

Length: 410
Mass: 45645
Checksum: 923DFC27C70AF604
Sequence:

MFILLVLVTG VSAFTTPTVV HTGKVSESPI TSEKPTVHGD NCQFRGREFK SELRLEGEPV 
VLRCPLAPHS DISSSSHSFL TWSKLDSSQL IPRDEPRMWV KGNILWILPA VQQDSGTYIC 
TFRNASHCEQ MSVELKVFKN TEASLPHVSY LQISALSTTG LLVCPDLKEF ISSNADGKIQ 
WYKGAILLDK GNKEFLSAGD PTRLLISNTS MDDAGYYRCV MTFTYNGQEY NITRNIELRV 
KGTTTEPIPV IISPLETIPA SLGSRLIVPC KVFLGTGTSS NTIVWWLANS TFISAAYPRG 
RVTEGLHHQY SENDENYVEV SLIFDPVTRE DLHTDFKCVA SNPRSSQSLH TTVKEVSSTF 
SWSIALAPLS LIILVVGAIW MRRRCKRRAG KTYGLTKLRT DNQDFPSSPN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Il1r2

Associated with

Other Information

A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. PubMed ID: 1833184

Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. PubMed ID: 8332913

Interleukin-1 receptor accessory protein interacts with the type II interleukin-1 receptor. PubMed ID: 9662436