Details for: Il1rap

Gene ID: 16180

Symbol: Il1rap

Ensembl ID: ENSMUSG00000022514

Description: interleukin 1 receptor accessory protein

Associated with

Other Information

Genular Protein ID: 4239506981

Symbol: IL1AP_MOUSE

Name: Interleukin-1 receptor accessory protein

UniProtKB Accession Codes:

Q61730 Q3UVZ1 Q8VCB9

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 3 CDD 2 CORUM 1 CPTAC 1 CTD 1 ChEBI 5 ChiTaRS 1 DIP 1 DNASU 1 EC 1 EMBL 8 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 26 Gene3D 2 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 2 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 4 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 6 RefSeq 3 Rhea 2 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 2 UniProtKB 1 VEuPathDB 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 7775431

Title: Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex.

PubMed ID: 7775431

DOI: 10.1074/jbc.270.23.13757

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9862719

Title: The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: a novel mechanism of regulation of IL-1 responsiveness.

PubMed ID: 9862719

PubMed ID: 10854325

Title: Tollip, a new component of the IL-1R1 pathway, links IRAK to the IL-1 receptor.

PubMed ID: 10854325

DOI: 10.1038/35014038

PubMed ID: 11880380

Title: Identification of essential regions in the cytoplasmic tail of interleukin-1 receptor accessory protein critical for interleukin-1 signaling.

PubMed ID: 11880380

DOI: 10.1074/jbc.m201000200

PubMed ID: 12659850

Title: Characterization of a cascade of protein interactions initiated at the IL-1 receptor.

PubMed ID: 12659850

DOI: 10.1016/s0006-291x(03)00385-1

PubMed ID: 15986350

Title: Soluble interleukin-1 receptor accessory protein ameliorates collagen-induced arthritis by a different mode of action from that of interleukin-1 receptor antagonist.

PubMed ID: 15986350

DOI: 10.1002/art.21108

PubMed ID: 17675517

Title: IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complex.

PubMed ID: 17675517

DOI: 10.4049/jimmunol.179.4.2551

PubMed ID: 18003919

Title: IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells.

PubMed ID: 18003919

DOI: 10.1073/pnas.0705939104

PubMed ID: 18450470

Title: The IL-1 receptor accessory protein (AcP) is required for IL-33 signaling and soluble AcP enhances the ability of soluble ST2 to inhibit IL-33.

PubMed ID: 18450470

DOI: 10.1016/j.cyto.2008.03.008

PubMed ID: 19481478

Title: A central nervous system-restricted isoform of the interleukin-1 receptor accessory protein modulates neuronal responses to interleukin-1.

PubMed ID: 19481478

DOI: 10.1016/j.immuni.2009.03.020

PubMed ID: 20200353

Title: The receptor tyrosine kinase c-Kit controls IL-33 receptor signaling in mast cells.

PubMed ID: 20200353

DOI: 10.1182/blood-2009-10-247411

PubMed ID: 21349253

Title: Production and functions of IL-33 in the central nervous system.

PubMed ID: 21349253

DOI: 10.1016/j.brainres.2011.02.045

PubMed ID: 21965679

Title: Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity.

PubMed ID: 21965679

DOI: 10.1074/jbc.m111.267922

PubMed ID: 22159118

Title: Neuron-specific effects of interleukin-1beta are mediated by a novel isoform of the IL-1 receptor accessory protein.

PubMed ID: 22159118

DOI: 10.1523/jneurosci.4067-11.2011

PubMed ID: 22778412

Title: Interleukin-1R3 mediates interleukin-1-induced potassium current increase through fast activation of Akt kinase.

PubMed ID: 22778412

DOI: 10.1073/pnas.1205207109

PubMed ID: 25908590

Title: Mechanisms of splicing-dependent trans-synaptic adhesion by PTPdelta-IL1RAPL1/IL-1RAcP for synaptic differentiation.

PubMed ID: 25908590

DOI: 10.1038/ncomms7926

Sequence Information:

  • Length: 570
  • Mass: 65741
  • Checksum: 4D4B07E0310AFDC5
  • Sequence:
    • MGLLWYLMSL SFYGILQSHA SERCDDWGLD TMRQIQVFED EPARIKCPLF EHFLKYNYST 
AHSSGLTLIW YWTRQDRDLE EPINFRLPEN RISKEKDVLW FRPTLLNDTG NYTCMLRNTT 
YCSKVAFPLE VVQKDSCFNS AMRFPVHKMY IEHGIHKITC PNVDGYFPSS VKPSVTWYKG 
CTEIVDFHNV LPEGMNLSFF IPLVSNNGNY TCVVTYPENG RLFHLTRTVT VKVVGSPKDA 
LPPQIYSPND RVVYEKEPGE ELVIPCKVYF SFIMDSHNEV WWTIDGKKPD DVTVDITINE 
SVSYSSTEDE TRTQILSIKK VTPEDLRRNY VCHARNTKGE AEQAAKVKQK VIPPRYTVEL 
ACGFGATVFL VVVLIVVYHV YWLEMVLFYR AHFGTDETIL DGKEYDIYVS YARNVEEEEF 
VLLTLRGVLE NEFGYKLCIF DRDSLPGGIV TDETLSFIQK SRRLLVVLSP NYVLQGTQAL 
LELKAGLENM ASRGNINVIL VQYKAVKDMK VKELKRAKTV LTVIKWKGEK SKYPQGRFWK 
QLQVAMPVKK SPRWSSNDKQ GLSYSSLKNV

Genular Protein ID: 2223543727

Symbol: E9Q6I2_MOUSE

Name: N/A

UniProtKB Accession Codes:

E9Q6I2

Database IDs:

AGR 1 ARBA 7 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 2 GeneTree 1 Genevisible 1 InterPro 9 MGI 2 MaxQB 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 4 PaxDb 1 PeptideAtlas 1 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 640
  • Mass: 73517
  • Checksum: F21C567FDC79B0C3
  • Sequence:
    • MGLLWYLMSL SFYGILQSHA SERCDDWGLD TMRQIQVFED EPARIKCPLF EHFLKYNYST 
AHSSGLTLIW YWTRQDRDLE EPINFRLPEN RISKEKDVLW FRPTLLNDTG NYTCMLRNTT 
YCSKVAFPLE VVQKDSCFNS AMRFPVHKMY IEHGIHKITC PNVDGYFPSS VKPSVTWYKG 
CTEIVDFHNV LPEGMNLSFF IPLVSNNGNY TCVVTYPENG RLFHLTRTVT VKVVGSPKDA 
LPPQIYSPND RVVYEKEPGE ELVIPCKVYF SFIMDSHNEV WWTIDGKKPD DVTVDITINE 
SVSYSSTEDE TRTQILSIKK VTPEDLRRNY VCHARNTKGE AEQAAKVKQK VIPPRYTVEL 
ACGFGATVFL VVVLIVVYHV YWLEMVLFYR AHFGTDETIL DGKEYDIYVS YARNVEEEEF 
VLLTLRGVLE NEFGYKLCIF DRDSLPGGNT VEAVFDFIQR SRRMIVVLSP DYVTEKSISM 
LEFKLGVMCQ NSIATKLIVV EYRPLEQPHP GIMQLKESVS FVSWKGEKSK HSGSKFWKAL 
RLALPLRSLS ASSGWNESCS SQSDISLDHV QRRSRLKEPP ELRSSERVSG AEPAPGTMSK 
HRGKPSAACR CCVTYCEGES HLRSKSRAEM HTHPQWETHL

Genular Protein ID: 3202732584

Symbol: Q3UEL3_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UEL3

Database IDs:

AGR 1 ARBA 4 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 ExpressionAtlas 1 GO 2 Gene3D 1 Genevisible 1 HOGENOM 1 InterPro 7 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 360
  • Mass: 41567
  • Checksum: E525471759FF7719
  • Sequence:
    • MGLLWYLMSL SFYGILQSHA SERCDDWGLD TMRQIQVFED EPARIKCPLF EHFLKYNYST 
AHSSGLTLIW YWTRQDRDLE EPINFRLPEN RISKEKDVLW FRPTLLNDTG NYTCMLRNTT 
YCSKVAFPLE VVQKDSCFNS AMRFPVHKMY IEHGIHKITC PNVDGYFPSS VKPSVTWYKG 
CTEIVDFHNV LPEGMNLSFF IPLVSNNGNY TCVVTYPENG RLFHLTRTVT VKVVGSPKDA 
LPPQIYSPND RVVYEKEPGE ELVIPCKVYF SFIMDSHNEV WWTIDGKKPD DVTVDITINE 
SVSYSSTEDE TRTQILSIKK VTPEDLRRNY VCHARNTKGE AEQAAKVKQK GNGCTEPMTL

Genular Protein ID: 91155514

Symbol: Q3V2X3_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3V2X3

Database IDs:

AGR 1 ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 4 Gene3D 2 Genevisible 1 Google 1 InterPro 9 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 4 Pfam 4 RefSeq 2 SAM 3 SMART 2 SUPFAM 2

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 685
  • Mass: 78624
  • Checksum: E1EEC0B8E1BB235F
  • Sequence:
    • MGLLWYLMSL SFYGILQSHA SERCDDWGLD TMRQIQVFED EPARIKCPLF EHFLKYNYST 
AHSSGLTLIW YWTRQDRDLE EPINFRLPEN RISKEKDVLW FRPTLLNDTG NYTCMLRNTT 
YCSKVAFPLE VVQKDSCFNS AMRFPVHKMY IEHGIHKITC PNVDGYFPSS VKPSVTWYKG 
CTEIVDFHNV LPEGMNLSFF IPLVSNNGNY TCVVTYPENG RLFHLTRTVT VKVVGSPKDA 
LPPQIYSPND RVVYEKEPGE ELVIPCKVYF SFIMDSHNEV WWTIDGKKPD DVTVDITINE 
SVSYSSTEDE TRTQILSIKK VTPEDLRRNY VCHARNTKGE AEQAAKVKQK VIPPRYTVEL 
ACGFGATVFL VVVLIVVYHV YWLEMVLFYR AHFGTDETIL DGKEYDIYVS YARNVEEEEF 
VLLTLRGVLE NEFGYKLCIF DRDSLPGGNT VEAVFDFIQR SRRMIVVLSP DYVTEKSISM 
LEFKLGVMCQ NSIATKLIVV EYRPLEQPHP GIMQLKESVS FVSWKGEKSK HSGSKFWKAL 
RLALPLRSLS ASSGWNESCS SQSDISLDHV QRRSRLKEPP ELRSSERVSG AEPAPGTMSK 
HRGKPSAACR CCVTYCEGES HLRSKSRAEM HTHPQWETHL SKPPLQESES QWIQNGTRPE 
PAPQISALAL RHFTDLSNNN DFYIL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.