Genular: Defining Cellular Identity and Function

Details for: Il2rb

Gene ID: 16185

Symbol: Il2rb

Ensembl ID: ENSMUSG00000068227

Description: interleukin 2 receptor, beta chain

Associated with

Cytokine signaling in immune system
(R-MMU-1280215)
Immune system
(R-MMU-168256)
Interleukin-2 family signaling
(R-MMU-451927)
Interleukin-2 signaling
(R-MMU-9020558)
Interleukin-3, interleukin-5 and gm-csf signaling
(R-MMU-512988)
Interleukin-15 signaling
(R-MMU-8983432)
Interleukin receptor shc signaling
(R-MMU-912526)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Raf/map kinase cascade
(R-MMU-5673001)
Signaling by interleukins
(R-MMU-449147)
Signal transduction
(R-MMU-162582)
Cell surface
(GO:0009986)
Coreceptor activity
(GO:0015026)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytokine receptor activity
(GO:0004896)
External side of plasma membrane
(GO:0009897)
Immunoglobulin mediated immune response
(GO:0016064)
Interleukin-2 binding
(GO:0019976)
Interleukin-2 receptor activity
(GO:0004911)
Interleukin-2-mediated signaling pathway
(GO:0038110)
Interleukin-15 receptor activity
(GO:0042010)
Interleukin-15-mediated signaling pathway
(GO:0035723)
Membrane
(GO:0016020)
Negative regulation of apoptotic process
(GO:0043066)
Plasma membrane
(GO:0005886)
Positive regulation of phagocytosis
(GO:0050766)

Other Information

Proteins

Interleukin-2 receptor subunit beta

Genular Protein ID: 3313010050

Symbol: IL2RB_MOUSE

Name: Interleukin-2 receptor subunit beta

UniProtKB Accession Codes:

P16297 Q3TZT2

Database IDs:

Citations:

PubMed ID: 2155425

Title: Murine interleukin 2 receptor beta chain: dysregulated gene expression in lymphoma line EL-4 caused by a promoter insertion.

PubMed ID: 2155425

DOI: 10.1073/pnas.87.5.1806

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

Sequence Information:

Length: 539
Mass: 60539
Checksum: 365C9D206E86FE14
Sequence:

MATIALPWSL SLYVFLLLLA TPWASAAVKN CSHLECFYNS RANVSCMWSH EEALNVTTCH 
VHAKSNLRHW NKTCELTLVR QASWACNLIL GSFPESQSLT SVDLLDINVV CWEEKGWRRV 
KTCDFHPFDN LRLVAPHSLQ VLHIDTQRCN ISWKVSQVSH YIEPYLEFEA RRRLLGHSWE 
DASVLSLKQR QQWLFLEMLI PSTSYEVQVR VKAQRNNTGT WSPWSQPLTF RTRPADPMKE 
ILPMSWLRYL LLVLGCFSGF FSCVYILVKC RYLGPWLKTV LKCHIPDPSE FFSQLSSQHG 
GDLQKWLSSP VPLSFFSPSG PAPEISPLEV LDGDSKAVQL LLLQKDSAPL PSPSGHSQAS 
CFTNQGYFFF HLPNALEIES CQVYFTYDPC VEEEVEEDGS RLPEGSPHPP LLPLAGEQDD 
YCAFPPRDDL LLFSPSLSTP NTAYGGSRAP EERSPLSLHE GLPSLASRDL MGLQRPLERM 
PEGDGEGLSA NSSGEQASVP EGNLHGQDQD RGQGPILTLN TDAYLSLQEL QAQDSVHLI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.