Genular: Defining Cellular Identity and Function

Details for: Il2rg

Gene ID: 16186

Symbol: Il2rg

Ensembl ID: ENSMUSG00000031304

Description: interleukin 2 receptor, gamma chain

Associated with

Cytokine signaling in immune system
(R-MMU-1280215)
Immune system
(R-MMU-168256)
Interleukin-2 family signaling
(R-MMU-451927)
Interleukin-2 signaling
(R-MMU-9020558)
Interleukin-3, interleukin-5 and gm-csf signaling
(R-MMU-512988)
Interleukin-4 and interleukin-13 signaling
(R-MMU-6785807)
Interleukin-7 signaling
(R-MMU-1266695)
Interleukin-9 signaling
(R-MMU-8985947)
Interleukin-15 signaling
(R-MMU-8983432)
Interleukin-21 signaling
(R-MMU-9020958)
Interleukin receptor shc signaling
(R-MMU-912526)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Raf/map kinase cascade
(R-MMU-5673001)
Signaling by interleukins
(R-MMU-449147)
Signal transduction
(R-MMU-162582)
B cell differentiation
(GO:0030183)
Cd4-positive, cd25-positive, alpha-beta regulatory t cell differentiation
(GO:0002361)
Cell surface
(GO:0009986)
Coreceptor activity
(GO:0015026)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytokine binding
(GO:0019955)
Cytokine receptor activity
(GO:0004896)
Endoplasmic reticulum
(GO:0005783)
External side of plasma membrane
(GO:0009897)
Gene expression
(GO:0010467)
Interleukin-2 binding
(GO:0019976)
Interleukin-2-mediated signaling pathway
(GO:0038110)
Interleukin-9-mediated signaling pathway
(GO:0038113)
Interleukin-15 receptor activity
(GO:0042010)
Interleukin-15-mediated signaling pathway
(GO:0035723)
Lymphocyte differentiation
(GO:0030098)
Mature b cell differentiation
(GO:0002335)
Membrane
(GO:0016020)
Nucleoplasm
(GO:0005654)
Plasma membrane
(GO:0005886)
Positive regulation of b cell differentiation
(GO:0045579)
Positive regulation of cd4-positive, cd25-positive, alpha-beta regulatory t cell differentiation
(GO:0032831)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of phagocytosis
(GO:0050766)
Positive regulation of t cell differentiation in thymus
(GO:0033089)
Receptor complex
(GO:0043235)
Regulation of gene expression
(GO:0010468)
T cell differentiation in thymus
(GO:0033077)

Other Information

Proteins

Cytokine receptor common subunit gamma
V5SIM2_MOUSE

Genular Protein ID: 2464011908

Symbol: IL2RG_MOUSE

Name: Cytokine receptor common subunit gamma

UniProtKB Accession Codes:

P34902

Database IDs:

Citations:

PubMed ID: 8503926

Title: Cloning of the mouse interleukin 2 receptor gamma chain: demonstration of functional differences between the mouse and human receptors.

PubMed ID: 8503926

DOI: 10.1006/bbrc.1993.1631

PubMed ID: 8378320

Title: Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression.

PubMed ID: 8378320

DOI: 10.1073/pnas.90.18.8464

PubMed ID: 8359699

Title: Cloning and sequencing of the cDNA encoding a mouse IL-2 receptor gamma.

PubMed ID: 8359699

DOI: 10.1016/0378-1119(93)90436-7

PubMed ID: 7805729

Title: The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus.

PubMed ID: 7805729

DOI: 10.1002/eji.1830241214

PubMed ID: 8750189

Title: Molecular mechanisms regulating the hyaluronan binding activity of the adhesion protein CD44.

PubMed ID: 8750189

DOI: 10.1007/bf01052626

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7718508

Title: Sharing of the IL-2 receptor gamma chain with the functional IL-9 receptor complex.

PubMed ID: 7718508

DOI: 10.1093/intimm/7.1.115

Sequence Information:

Length: 369
Mass: 42241
Checksum: CB2D5AB459077AC7
Sequence:

MLKLLLSPRS FLVLQLLLLR AGWSSKVLMS SANEDIKADL ILTSTAPEHL SAPTLPLPEV 
QCFVFNIEYM NCTWNSSSEP QATNLTLHYR YKVSDNNTFQ ECSHYLFSKE ITSGCQIQKE 
DIQLYQTFVV QLQDPQKPQR RAVQKLNLQN LVIPRAPENL TLSNLSESQL ELRWKSRHIK 
ERCLQYLVQY RSNRDRSWTE LIVNHEPRFS LPSVDELKRY TFRVRSRYNP ICGSSQQWSK 
WSQPVHWGSH TVEENPSLFA LEAVLIPVGT MGLIITLIFV YCWLERMPPI PPIKNLEDLV 
TEYQGNFSAW SGVSKGLTES LQPDYSERFC HVSEIPPKGG ALGEGPGGSP CSLHSPYWPP 
PCYSLKPEA

Genular Protein ID: 4055382966

Symbol: V5SIM2_MOUSE

Name: N/A

UniProtKB Accession Codes:

V5SIM2

Database IDs:

Sequence Information:

Length: 266
Mass: 30593
Checksum: F24D6AD13F3FD2F4
Sequence:

MLKLLLSPRS FLVLQLLLLR AGWSSKVLMS SANEDIKADL ILTSTAPEHL SAPTLPLPEV 
QCFVFNIEYM NCTWNSSSEP QATNLTLHYR CKVSDNNTFQ ECSHYLFSKE ITSGCQIQKE 
DIQLYQTFVV QLQDPQKPQR RAVQKLNLQN LVIPRAPENL TLSNLSESQL ELRWKSRHIK 
ERCLQYLVQY RSNRDRSWTE LIVNHEPRFS LPSVDELKRE SFLVCTGSCA YPCWHHGVDY 
YPDLCVLLVG TNASNSPHQE SRGSGY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Il2rg

Associated with

Other Information

Cloning of the mouse interleukin 2 receptor gamma chain: demonstration of functional differences between the mouse and human receptors. PubMed ID: 8503926

Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression. PubMed ID: 8378320

Cloning and sequencing of the cDNA encoding a mouse IL-2 receptor gamma. PubMed ID: 8359699

The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus. PubMed ID: 7805729

Molecular mechanisms regulating the hyaluronan binding activity of the adhesion protein CD44. PubMed ID: 8750189

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Sharing of the IL-2 receptor gamma chain with the functional IL-9 receptor complex. PubMed ID: 7718508