Genular: Defining Cellular Identity and Function

Details for: Il5

Gene ID: 16191

Symbol: Il5

Ensembl ID: ENSMUSG00000036117

Description: interleukin 5

Associated with

Cytokine signaling in immune system
(R-MMU-1280215)
Immune system
(R-MMU-168256)
Interleukin-2 family signaling
(R-MMU-451927)
Interleukin-3, interleukin-5 and gm-csf signaling
(R-MMU-512988)
Interleukin receptor shc signaling
(R-MMU-912526)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Raf/map kinase cascade
(R-MMU-5673001)
Signaling by interleukins
(R-MMU-449147)
Signal transduction
(R-MMU-162582)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytokine activity
(GO:0005125)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Growth factor activity
(GO:0008083)
Immune response
(GO:0006955)
Interleukin-5 receptor binding
(GO:0005137)
Interleukin-5-mediated signaling pathway
(GO:0038043)
Peptidyl-tyrosine phosphorylation
(GO:0018108)
Positive regulation of b cell proliferation
(GO:0030890)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of dna-binding transcription factor activity
(GO:0051091)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of eosinophil differentiation
(GO:0045645)
Positive regulation of immunoglobulin production
(GO:0002639)
Positive regulation of peptidyl-tyrosine phosphorylation
(GO:0050731)
Positive regulation of podosome assembly
(GO:0071803)
Positive regulation of receptor signaling pathway via jak-stat
(GO:0046427)

Other Information

Proteins

Interleukin-5

Genular Protein ID: 3263325872

Symbol: IL5_MOUSE

Name: Interleukin-5

UniProtKB Accession Codes:

P04401

Database IDs:

Citations:

PubMed ID: 3133208

Title: Isolation, structure and expression of cDNA and genomic clones for murine eosinophil differentiation factor. Comparison with other eosinophilopoietic lymphokines and identity with interleukin-5.

PubMed ID: 3133208

DOI: 10.1111/j.1432-1033.1988.tb14104.x

PubMed ID: 3024009

Title: Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II.

PubMed ID: 3024009

DOI: 10.1038/324070a0

PubMed ID: 3078564

Title: Molecular cloning and structure of the mouse interleukin-5 gene.

PubMed ID: 3078564

DOI: 10.3109/08977198809000246

PubMed ID: 3128631

Title: Recombinant interleukin 2 or 5, but not 3 or 4, induces maturation of resting mouse B lymphocytes and propagates proliferation of activated B cell blasts.

PubMed ID: 3128631

DOI: 10.1084/jem.167.4.1377

PubMed ID: 2215480

Title: Structural comparison of murine T-cell (B151K12)-derived T-cell-replacing factor (IL-5) with rIL-5: dimer formation is essential for the expression of biological activity.

PubMed ID: 2215480

DOI: 10.1016/0161-5890(90)90158-v

PubMed ID: 1873482

Title: Analysis of interleukin 5 receptors on murine eosinophils: a comparison with receptors on B13 cells.

PubMed ID: 1873482

DOI: 10.1016/1043-4666(91)90503-6

PubMed ID: 10444455

Title: IL-5 contributes to worm expulsion and muscle hypercontractility in a primary T. spiralis infection.

PubMed ID: 10444455

DOI: 10.1152/ajpgi.1999.277.2.g400

Sequence Information:

Length: 133
Mass: 15410
Checksum: C6DC091682452AF4
Sequence:

MRRMLLHLSV LTLSCVWATA MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ 
LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE 
FLGVMSTEWA MEG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Il5

Associated with

Other Information

Isolation, structure and expression of cDNA and genomic clones for murine eosinophil differentiation factor. Comparison with other eosinophilopoietic lymphokines and identity with interleukin-5. PubMed ID: 3133208

Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II. PubMed ID: 3024009

Molecular cloning and structure of the mouse interleukin-5 gene. PubMed ID: 3078564

Recombinant interleukin 2 or 5, but not 3 or 4, induces maturation of resting mouse B lymphocytes and propagates proliferation of activated B cell blasts. PubMed ID: 3128631

Structural comparison of murine T-cell (B151K12)-derived T-cell-replacing factor (IL-5) with rIL-5: dimer formation is essential for the expression of biological activity. PubMed ID: 2215480

Analysis of interleukin 5 receptors on murine eosinophils: a comparison with receptors on B13 cells. PubMed ID: 1873482

IL-5 contributes to worm expulsion and muscle hypercontractility in a primary T. spiralis infection. PubMed ID: 10444455