Genular: Defining Cellular Identity and Function

Details for: Il7

Gene ID: 16196

Symbol: Il7

Ensembl ID: ENSMUSG00000040329

Description: interleukin 7

Associated with

Cytokine signaling in immune system
(R-MMU-1280215)
Immune system
(R-MMU-168256)
Interleukin-7 signaling
(R-MMU-1266695)
Signaling by interleukins
(R-MMU-449147)
B cell proliferation
(GO:0042100)
Bone resorption
(GO:0045453)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytokine activity
(GO:0005125)
Cytokine receptor binding
(GO:0005126)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Extrinsic apoptotic signaling pathway
(GO:0097191)
Growth factor activity
(GO:0008083)
Homeostasis of number of cells within a tissue
(GO:0048873)
Immune response
(GO:0006955)
Interleukin-7 receptor binding
(GO:0005139)
Negative regulation of catalytic activity
(GO:0043086)
Negative regulation of extrinsic apoptotic signaling pathway
(GO:2001237)
Negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
(GO:2001240)
Organ growth
(GO:0035265)
Positive regulation of b cell differentiation
(GO:0045579)
Positive regulation of b cell proliferation
(GO:0030890)
Positive regulation of chemokine production
(GO:0032722)
Positive regulation of cytokine-mediated signaling pathway
(GO:0001961)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of organ growth
(GO:0046622)
Positive regulation of t cell differentiation
(GO:0045582)
Regulation of gene expression
(GO:0010468)
Regulation of peptidyl-tyrosine phosphorylation
(GO:0050730)
T cell lineage commitment
(GO:0002360)

Other Information

Proteins

Interleukin-7
Q3UT18_MOUSE

Genular Protein ID: 3405013861

Symbol: IL7_MOUSE

Name: Interleukin-7

UniProtKB Accession Codes:

P10168

Database IDs:

Citations:

PubMed ID: 3259677

Title: Stimulation of B-cell progenitors by cloned murine interleukin-7.

PubMed ID: 3259677

DOI: 10.1038/333571a0

PubMed ID: 2329282

Title: Characterization of the human and murine IL-7 genes.

PubMed ID: 2329282

PubMed ID: 7699333

Title: Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

PubMed ID: 7699333

DOI: 10.1084/jem.181.4.1519

PubMed ID: 28811625

Title: Interleukin-7 in the transition of bone marrow progenitors to the thymus.

PubMed ID: 28811625

DOI: 10.1038/icb.2017.68

Sequence Information:

Length: 154
Mass: 17727
Checksum: CBAAB7A1A7516A42
Sequence:

MFHVSFRYIF GIPPLILVLL PVTSSECHIK DKEGKAYESV LMISIDELDK MTGTDSNCPN 
NEPNFFRKHV CDDTKEAAFL NRAARKLKQF LKMNISEEFN VHLLTVSQGT QTLVNCTSKE 
EKNVKEQKKN DACFLKRLLR EIKTCWNKIL KGSI

Genular Protein ID: 3543354013

Symbol: Q3UT18_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UT18

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 113
Mass: 13066
Checksum: 113817BA31C286E0
Sequence:

MISIDELDKM TGTDSNCPNN EPNFFRKHVC DDTKEAAFLN RAARKLKQFL KMNISEEFNV 
HLLTVSQGTQ TLVNCTSKEE KNVKEQKKND ACFLKRLLRE IKTCWNKILK GSI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Il7

Associated with

Other Information

Stimulation of B-cell progenitors by cloned murine interleukin-7. PubMed ID: 3259677

Characterization of the human and murine IL-7 genes. PubMed ID: 2329282

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. PubMed ID: 7699333

Interleukin-7 in the transition of bone marrow progenitors to the thymus. PubMed ID: 28811625

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303