Genular: Defining Cellular Identity and Function

Details for: Incenp

Gene ID: 16319

Symbol: Incenp

Ensembl ID: ENSMUSG00000024660

Description: inner centromere protein

Associated with

Amplification of signal from the kinetochores
(R-MMU-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-MMU-141444)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Eml4 and nudc in mitotic spindle formation
(R-MMU-9648025)
Metabolism of proteins
(R-MMU-392499)
Mitotic anaphase
(R-MMU-68882)
Mitotic metaphase and anaphase
(R-MMU-2555396)
Mitotic prometaphase
(R-MMU-68877)
Mitotic spindle checkpoint
(R-MMU-69618)
M phase
(R-MMU-68886)
Post-translational protein modification
(R-MMU-597592)
Resolution of sister chromatid cohesion
(R-MMU-2500257)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate formins
(R-MMU-5663220)
Separation of sister chromatids
(R-MMU-2467813)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Sumo e3 ligases sumoylate target proteins
(R-MMU-3108232)
Sumoylation
(R-MMU-2990846)
Sumoylation of dna replication proteins
(R-MMU-4615885)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Central element
(GO:0000801)
Chromocenter
(GO:0010369)
Chromosome
(GO:0005694)
Chromosome, centromeric region
(GO:0000775)
Chromosome passenger complex
(GO:0032133)
Chromosome segregation
(GO:0007059)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Cytosol
(GO:0005829)
Kinetochore
(GO:0000776)
Lateral element
(GO:0000800)
Meiotic spindle midzone
(GO:1990385)
Meiotic spindle midzone assembly
(GO:0051257)
Metaphase chromosome alignment
(GO:0051310)
Microtubule
(GO:0005874)
Microtubule cytoskeleton
(GO:0015630)
Midbody
(GO:0030496)
Mitotic cell cycle
(GO:0000278)
Mitotic cytokinesis
(GO:0000281)
Mitotic spindle midzone assembly
(GO:0051256)
Mitotic spindle organization
(GO:0007052)
Molecular function activator activity
(GO:0140677)
Nuclear body
(GO:0016604)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Pericentric heterochromatin
(GO:0005721)
Positive regulation of attachment of mitotic spindle microtubules to kinetochore
(GO:1902425)
Positive regulation of mitotic cell cycle spindle assembly checkpoint
(GO:0090267)
Positive regulation of mitotic cytokinesis
(GO:1903490)
Positive regulation of mitotic sister chromatid separation
(GO:1901970)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein-containing complex
(GO:0032991)
Spindle
(GO:0005819)
Synaptonemal complex
(GO:0000795)

Other Information

Proteins

Inner centromere protein

Genular Protein ID: 1817536223

Symbol: INCE_MOUSE

Name: Inner centromere protein

UniProtKB Accession Codes:

Q9WU62 Q7TN28 Q8BGN4 Q8CGI4

Database IDs:

Citations:

PubMed ID: 10087305

Title: Cloning, expression, and promoter structure of a mammalian inner centromere protein (INCENP).

PubMed ID: 10087305

DOI: 10.1007/s003359901014

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12660166

Title: Pericentric heterochromatin becomes enriched with H2A.Z during early mammalian development.

PubMed ID: 12660166

DOI: 10.1093/emboj/cdg160

PubMed ID: 12584241

Title: Dynamic relocalization of the chromosomal passenger complex proteins inner centromere protein (INCENP) and aurora-B kinase during male mouse meiosis.

PubMed ID: 12584241

DOI: 10.1242/jcs.00330

PubMed ID: 14722118

Title: Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis.

PubMed ID: 14722118

DOI: 10.1074/jbc.m311128200

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20571061

Title: Sialic acid-focused quantitative mouse serum glycoproteomics by multiple reaction monitoring assay.

PubMed ID: 20571061

DOI: 10.1074/mcp.m110.000430

Sequence Information:

Length: 880
Mass: 101209
Checksum: 92169889A921FEFC
Sequence:

MGTTAPGPIC LLDLCDQKLL DFVCNVDNKD FMWLKEIEEE AERMFIREFS NEPELMPKTP 
SQKNRRKKRR VSNIQDENRD PVRKRLSRRK SRSSQVGTRH LRSKPVTIVE ENGFPVLQRI 
TRATAAAAAA AAAASVASAS SSSTAGSPTV LTKKAVVEIS TSERLSAELQ LTKLKGSLPP 
SPVSQGTLTS EEELTPKKSE AGKLDSVTVN SLKATPQSPK NRGVGEGRSV SKLKIARASW 
GLQDSPGSTD SPWQERVLSP ILLNNILPTT AKSPLGNIRS VRRSLISQDS QVPLASKYNL 
VAKQENGSRR SSRRIAKKAG KEPEASARII CHSYLERLLN VEVPQNVGLE QEPVEVAEPE 
EAEEEQEVSK NSGCPSKPRS ATKIAISTPT SKPAAAGQTT TVEEQEAELD QTDGHREPPQ 
SVRRKRSYKQ AISEPDEEQL EDEELQPCQN KTPSPPCPAN KVVRPLRTFL HTVQKNQMLM 
TPTLASRSSV MKSFIKRNTP LRVDPKCSFV EKERQRLESL RRKEEAEQRR RQKVEEDKRR 
RLEEVKLKRE ERLRKVLQAR ERVEQMKEEK KKQIEQKFAQ IDEKTEKAKE ERLAEKAKKK 
ATAKKMEEVE ARRKQEEEAR RLRWLQQEEE ERRHQEMLQR KKEEEQERRK AAEARRLAEQ 
REQERRREQE RREQERREQE RREQERKEQE RREQEQERLR AKREMQEREK ALRLQKERLQ 
KELEEKKRKE EQQRLAEQQL QEEQAKKAKE VAAARKVLNM TVDVQSPVCT SYQMTPQGPK 
SIPKISVDDY GMDLNSDDST DDESHPRKPI PSWAKGTQLS QAIVHQYYHP PNILELFGSI 
LPLDLEDIFK KRKTRYHKRT SSAVWNSPPL KATMVPSSGD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Incenp

Associated with

Other Information

Cloning, expression, and promoter structure of a mammalian inner centromere protein (INCENP). PubMed ID: 10087305

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Pericentric heterochromatin becomes enriched with H2A.Z during early mammalian development. PubMed ID: 12660166

Dynamic relocalization of the chromosomal passenger complex proteins inner centromere protein (INCENP) and aurora-B kinase during male mouse meiosis. PubMed ID: 12584241

Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis. PubMed ID: 14722118

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Sialic acid-focused quantitative mouse serum glycoproteomics by multiple reaction monitoring assay. PubMed ID: 20571061