Genular: Defining Cellular Identity and Function

Details for: Inhba

Gene ID: 16323

Symbol: Inhba

Ensembl ID: ENSMUSG00000041324

Description: inhibin beta-A

Associated with

Antagonism of activin by follistatin
(R-MMU-2473224)
Glycoprotein hormones
(R-MMU-209822)
Metabolism of proteins
(R-MMU-392499)
Peptide hormone biosynthesis
(R-MMU-209952)
Peptide hormone metabolism
(R-MMU-2980736)
Signaling by activin
(R-MMU-1502540)
Signaling by bmp
(R-MMU-201451)
Signaling by tgfb family members
(R-MMU-9006936)
Signal transduction
(R-MMU-162582)
Activin a complex
(GO:0043509)
Activin receptor signaling pathway
(GO:0032924)
Autophagy
(GO:0006914)
Cardiac fibroblast cell development
(GO:0060936)
Cellular response to cholesterol
(GO:0071397)
Cellular response to follicle-stimulating hormone stimulus
(GO:0071372)
Cytokine activity
(GO:0005125)
Endodermal cell differentiation
(GO:0035987)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Extrinsic apoptotic signaling pathway
(GO:0097191)
Eyelid development in camera-type eye
(GO:0061029)
Gabaergic neuron differentiation
(GO:0097154)
Growth factor activity
(GO:0008083)
Hair follicle development
(GO:0001942)
Hematopoietic progenitor cell differentiation
(GO:0002244)
Hemoglobin biosynthetic process
(GO:0042541)
Hormone activity
(GO:0005179)
Identical protein binding
(GO:0042802)
Inhibin a complex
(GO:0043512)
Male gonad development
(GO:0008584)
Mesodermal cell differentiation
(GO:0048333)
Mesoderm formation
(GO:0001707)
Negative regulation of cell growth
(GO:0030308)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of g1/s transition of mitotic cell cycle
(GO:2000134)
Negative regulation of hair follicle development
(GO:0051799)
Odontogenesis
(GO:0042476)
Ovarian follicle development
(GO:0001541)
Peptide hormone binding
(GO:0017046)
Perinuclear region of cytoplasm
(GO:0048471)
Positive regulation of collagen biosynthetic process
(GO:0032967)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of erythrocyte differentiation
(GO:0045648)
Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
(GO:2001241)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of ovulation
(GO:0060279)
Positive regulation of protein metabolic process
(GO:0051247)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of smad protein signal transduction
(GO:0060391)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Progesterone secretion
(GO:0042701)
Protein-containing complex binding
(GO:0044877)
Regulation of follicle-stimulating hormone secretion
(GO:0046880)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Roof of mouth development
(GO:0060021)
Signaling receptor binding
(GO:0005102)
Smad protein signal transduction
(GO:0060395)
Striatal medium spiny neuron differentiation
(GO:0021773)
Transcription by rna polymerase ii
(GO:0006366)
Type ii activin receptor binding
(GO:0070699)

Other Information

Proteins

Inhibin beta A chain

Genular Protein ID: 2709737907

Symbol: INHBA_MOUSE

Name: Inhibin beta A chain

UniProtKB Accession Codes:

Q04998

Database IDs:

Citations:

PubMed ID: 8330535

Title: Activins are expressed in preimplantation mouse embryos and in ES and EC cells and are regulated on their differentiation.

PubMed ID: 8330535

DOI: 10.1242/dev.117.2.711

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2133547

Title: A mesoderm-inducing factor produced by WEHI-3 murine myelomonocytic leukemia cells is activin A.

PubMed ID: 2133547

DOI: 10.1242/dev.110.2.435

Sequence Information:

Length: 424
Mass: 47392
Checksum: 80C251B8754A7213
Sequence:

MPLLWLRGFL LASCWIIVRS SPTPGSEGHG SAPDCPSCAL ATLPKDGPNS QPEMVEAVKK 
HILNMLHLKK RPDVTQPVPK AALLNAIRKL HVGKVGENGY VEIEDDIGRR AEMNELMEQT 
SEIITFAESG TARKTLHFEI SKEGSDLSVV ERAEVWLFLK VPKANRTRTK VTIRLFQQQK 
HPQGSLDTGD EAEEMGLKGE RSELLLSEKV VDARKSTWHI FPVSSSIQRL LDQGKSSLDV 
RIACEQCQES GASLVLLGKK KKKEVDGDGK KKDGSDGGLE EEKEQSHRPF LMLQARQSED 
HPHRRRRRGL ECDGKVNICC KKQFFVSFKD IGWNDWIIAP SGYHANYCEG ECPSHIAGTS 
GSSLSFHSTV INHYRMRGHS PFANLKSCCV PTKLRPMSML YYDDGQNIIK KDIQNMIVEE 
CGCS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.