Genular: Defining Cellular Identity and Function

Details for: Eif3e

Gene ID: 16341

Symbol: Eif3e

Ensembl ID: ENSMUSG00000022336

Description: eukaryotic translation initiation factor 3, subunit E

Associated with

Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
(R-MMU-72662)
Cap-dependent translation initiation
(R-MMU-72737)
Eukaryotic translation initiation
(R-MMU-72613)
Formation of a pool of free 40s subunits
(R-MMU-72689)
Formation of the ternary complex, and subsequently, the 43s complex
(R-MMU-72695)
Gtp hydrolysis and joining of the 60s ribosomal subunit
(R-MMU-72706)
L13a-mediated translational silencing of ceruloplasmin expression
(R-MMU-156827)
Metabolism of proteins
(R-MMU-392499)
Ribosomal scanning and start codon recognition
(R-MMU-72702)
Translation initiation complex formation
(R-MMU-72649)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Eukaryotic translation initiation factor 3 complex
(GO:0005852)
Intracellular calcium ion homeostasis
(GO:0006874)
Nuclear-transcribed mrna catabolic process, nonsense-mediated decay
(GO:0000184)
Nucleus
(GO:0005634)
Pml body
(GO:0016605)
Positive regulation of intracellular protein transport
(GO:0090316)
Positive regulation of mrna binding
(GO:1902416)
Positive regulation of translation
(GO:0045727)
Postsynaptic density
(GO:0014069)
Translation
(GO:0006412)
Translational initiation
(GO:0006413)
Translation initiation factor activity
(GO:0003743)
Transmembrane transporter binding
(GO:0044325)

Other Information

Proteins

MMTV integration site 6

Genular Protein ID: 417286741

Symbol: EIF3E_MOUSE

Name: MMTV integration site 6

UniProtKB Accession Codes:

P60229 O43902 Q64058 Q64059 Q64252

Database IDs:

Citations:

PubMed ID: 7853537

Title: Int-6, a highly conserved, widely expressed gene, is mutated by mouse mammary tumor virus in mammary preneoplasia.

PubMed ID: 7853537

DOI: 10.1128/jvi.69.3.1932-1938.1995

PubMed ID: 9260927

Title: Characterization of the INT6 mammary tumor gene product.

PubMed ID: 9260927

DOI: 10.1089/dna.1997.16.839

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17581632

Title: Reconstitution reveals the functional core of mammalian eIF3.

PubMed ID: 17581632

DOI: 10.1038/sj.emboj.7601765

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 445
Mass: 52221
Checksum: A5368651DD0DDD0C
Sequence:

MAEYDLTTRI AHFLDRHLVF PLLEFLSVKE IYNEKELLQG KLDLLSDTNM VDFAMDVYKN 
LYSDDIPHAL REKRTTVVAQ LKQLQAETEP IVKMFEDPET TRQMQSTRDG RMLFDYLADK 
HGFRQEYLDT LYRYAKFQYE CGNYSGAAEY LYFFRVLVPA TDRNALSSLW GKLASEILMQ 
NWDAAMEDLT RLKETIDNNS VSSPLQSLQQ RTWLIHWSLF VFFNHPKGRD NIIDLFLYQP 
QYLNAIQTMC PHILRYLTTA VITNKDVRKR RQVLKDLVKV IQQESYTYKD PITEFVECLY 
VNFDFDGAQK KLRECESVLV NDFFLVACLE DFIENARLFI FETFCRIHQC ISINMLADKL 
NMTPEEAERW IVNLIRNARL DAKIDSKLGH VVMGNNAVSP YQQVIEKTKS LSFRSQMLAM 
NIEKKLNQNS RSEAPNWATQ DSGFY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Eif3e

Associated with

Other Information

Int-6, a highly conserved, widely expressed gene, is mutated by mouse mammary tumor virus in mammary preneoplasia. PubMed ID: 7853537

Characterization of the INT6 mammary tumor gene product. PubMed ID: 9260927

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. PubMed ID: 15592455

Reconstitution reveals the functional core of mammalian eIF3. PubMed ID: 17581632

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. PubMed ID: 17525332

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079