Genular: Defining Cellular Identity and Function

Details for: Itga3

Gene ID: 16400

Symbol: Itga3

Ensembl ID: ENSMUSG00000001507

Description: integrin alpha 3

Associated with

Basigin interactions
(R-MMU-210991)
Cell surface interactions at the vascular wall
(R-MMU-202733)
Extracellular matrix organization
(R-MMU-1474244)
Hemostasis
(R-MMU-109582)
Integrin cell surface interactions
(R-MMU-216083)
Laminin interactions
(R-MMU-3000157)
Met activates ptk2 signaling
(R-MMU-8874081)
Met promotes cell motility
(R-MMU-8875878)
Signaling by met
(R-MMU-6806834)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signal transduction
(R-MMU-162582)
Anchoring junction
(GO:0070161)
Basolateral plasma membrane
(GO:0016323)
Behavior
(GO:0007610)
Cell-cell adhesion
(GO:0098609)
Cell-matrix adhesion
(GO:0007160)
Cell adhesion
(GO:0007155)
Cell adhesion mediated by integrin
(GO:0033627)
Cell periphery
(GO:0071944)
Cell projection
(GO:0042995)
Cell surface
(GO:0009986)
Collagen binding
(GO:0005518)
Dendritic spine maintenance
(GO:0097062)
Excitatory synapse
(GO:0060076)
Exploration behavior
(GO:0035640)
External side of plasma membrane
(GO:0009897)
Fibronectin binding
(GO:0001968)
Filopodium membrane
(GO:0031527)
Fusion of sperm to egg plasma membrane involved in single fertilization
(GO:0007342)
Glutamatergic synapse
(GO:0098978)
Growth cone
(GO:0030426)
Growth cone filopodium
(GO:1990812)
Integrin-mediated signaling pathway
(GO:0007229)
Integrin alpha3-beta1 complex
(GO:0034667)
Integrin binding
(GO:0005178)
Integrin complex
(GO:0008305)
Laminin binding
(GO:0043236)
Leukocyte migration
(GO:0050900)
Lung development
(GO:0030324)
Membrane
(GO:0016020)
Memory
(GO:0007613)
Negative regulation of cell projection organization
(GO:0031345)
Negative regulation of rho protein signal transduction
(GO:0035024)
Nephron development
(GO:0072006)
Neuromuscular junction
(GO:0031594)
Neuron migration
(GO:0001764)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Positive regulation of cell-substrate adhesion
(GO:0010811)
Positive regulation of epithelial cell migration
(GO:0010634)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of neuron projection development
(GO:0010976)
Positive regulation of protein localization to plasma membrane
(GO:1903078)
Postsynapse organization
(GO:0099173)
Postsynaptic membrane
(GO:0045211)
Presynaptic active zone membrane
(GO:0048787)
Protease binding
(GO:0002020)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein heterodimerization activity
(GO:0046982)
Receptor complex
(GO:0043235)
Regulation of bmp signaling pathway
(GO:0030510)
Regulation of transforming growth factor beta receptor signaling pathway
(GO:0017015)
Regulation of wnt signaling pathway
(GO:0030111)
Renal filtration
(GO:0097205)
Rho protein signal transduction
(GO:0007266)
Skin development
(GO:0043588)
Synapse
(GO:0045202)
Synaptic membrane
(GO:0097060)
Synaptic membrane adhesion
(GO:0099560)

Other Information

Proteins

Integrin alpha-3

Genular Protein ID: 3530835561

Symbol: ITA3_MOUSE

Name: Integrin alpha-3

UniProtKB Accession Codes:

Q62470 Q08441 Q08442 Q5SWA8 Q5SWB9 Q6P6I1

Database IDs:

Citations:

PubMed ID: 7759572

Title: cDNA cloning of mouse VLA-3 alpha subunit.

PubMed ID: 7759572

DOI: 10.1002/jcb.240570221

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1946438

Title: Cell type-specific integrin variants with alternative alpha chain cytoplasmic domains.

PubMed ID: 1946438

DOI: 10.1073/pnas.88.22.10183

PubMed ID: 15181153

Title: NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin.

PubMed ID: 15181153

DOI: 10.1091/mbc.e04-03-0236

PubMed ID: 19656770

Title: The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.

PubMed ID: 19656770

DOI: 10.1074/mcp.m900195-mcp200

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 1053
Mass: 116745
Checksum: 6A5E8FBDBA86D6E5
Sequence:

MGPGPCRVPR APGWLLRALA LMVAACGRVA FAFNLDTRFL VVKEAVNPGS LFGYSVALHR 
QTERQQRYLL LAGAPRDLAV GDDYTNRTGA VYLCPLTAHK DDCERMDISE KSDPDHHIIE 
DMWLGVTVAS QGPAGRVLVC AHRYTKVLWS GLEDQRRMVG KCYVRGNDLQ LDPGDDWQTY 
HNEMCNSNTD YLQTGMCQLG TSGGFTQNTV YFGAPGAYNW KGNSYMIQRK DWDLSEYSYR 
GSEEQGNLYI GYTVQVGNAI LHPTDIITVV TGAPRHQHMG AVFLLKQESG GDLQRKQVLK 
GTQVGAYFGS AIALADLNND GWQDLLVGAP YYFERKEEVG GAVYVFMNQA GASFPDQPSL 
LLHGPSRSAF GISIASIGDI NQDGFQDIAV GAPFEGLGKV YIYHSSSGGL LRQPQQIIHG 
EKLGLPGLAT FGYSLSGKMD VDENLYPDLL VGSLSDHIVL LRARPVINIL HRTLVARPAV 
LDPALCTATS CVQVELCFAY NQSAGNPNYR RNITLAYTLE ADRDRRPPRL RFARSQSSVF 
HGFFSMPETH CQTLELLLMD NVRDKLRPIV IAMNYSLPLR MPDRLKLGLR SLDAYPVLNQ 
AQAMENHTEV HFQKECGPDN KCDSNLQMRA AFLSEQLQPL SRLQYSRDTK KLFLSINVTN 
SPSSQRAGED AHEALLTLEV PSALLLSSVR PSGTCQANNE TILCELGNPF KRNQRMELLI 
AFEVIGVTLH TRDLPVLLQL STSSHQDNLQ PVLLTLQVDY TLQASLSLMN HRLQSFFGGT 
VMGEAAMKTA EDVGSPLKYE FQVSPVGDGL AALGTLVLGL EWPYEVTNGK WLLYPTEITI 
HSNGSWPCQP SGNLVNPLNL TLSDPGVTPL SPQRRRRQLD PGGDQSSPPV TLAAAKKAKS 
ETVLTCSNGR ARCVWLECPL PDTSNITNVT VKARVWNSTF IEDYKDFDRV RVDGWATLFL 
RTSIPTINME NKTTWFSVDI DSELVEELPA EIELWLVLVA VGAGLLLLGL IILLLWKCGF 
FKRARTRALY EAKRQKAEMK SQPSETERLT DDY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Itga3

Associated with

Other Information

cDNA cloning of mouse VLA-3 alpha subunit. PubMed ID: 7759572

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Cell type-specific integrin variants with alternative alpha chain cytoplasmic domains. PubMed ID: 1946438

NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin. PubMed ID: 15181153

The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation. PubMed ID: 19656770

Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. PubMed ID: 19349973

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079