Details for: Itgb1

Gene ID: 16412

Symbol: Itgb1

Ensembl ID: ENSMUSG00000025809

Description: integrin beta 1 (fibronectin receptor beta)

Associated with

Other Information

Genular Protein ID: 3036568884

Symbol: ITB1_MOUSE

Name: Fibronectin receptor subunit beta

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 3262537

Title: Murine mRNA for the beta-subunit of integrin is increased in BALB/c-3T3 cells entering the G1 phase from the G0 state.

PubMed ID: 3262537

DOI: 10.1016/0014-5793(88)80503-9

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2523953

Title: Molecular cloning of a murine fibronectin receptor and its expression during inflammation. Expression of VLA-5 is increased in activated peritoneal macrophages in a manner discordant from major histocompatibility complex class II.

PubMed ID: 2523953

DOI: 10.1084/jem.169.5.1589

PubMed ID: 2521606

Title: Coordinate induction of fibronectin, fibronectin receptor, tropomyosin, and actin genes in serum-stimulated fibroblasts.

PubMed ID: 2521606

DOI: 10.1016/0014-4827(89)90080-3

PubMed ID: 8567725

Title: Beta 1D integrin displaces the beta 1A isoform in striated muscles: localization at junctional structures and signaling potential in nonmuscle cells.

PubMed ID: 8567725

DOI: 10.1083/jcb.132.1.211

PubMed ID: 8870969

Title: Genomic organization of the mouse beta 1 gene: conservation of the beta 1D but not of the beta 1B and beta 1C integrin splice variants.

PubMed ID: 8870969

DOI: 10.3109/15419069609010759

PubMed ID: 9553049

Title: Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development.

PubMed ID: 9553049

DOI: 10.1101/gad.12.8.1202

PubMed ID: 10634791

Title: Requirement of CD9 on the egg plasma membrane for fertilization.

PubMed ID: 10634791

DOI: 10.1126/science.287.5451.321

PubMed ID: 11805835

Title: Fibulin-5/DANCE is essential for elastogenesis in vivo.

PubMed ID: 11805835

DOI: 10.1038/415171a

PubMed ID: 12189152

Title: The tetraspan protein epithelial membrane protein-2 interacts with beta1 integrins and regulates adhesion.

PubMed ID: 12189152

DOI: 10.1074/jbc.m206868200

PubMed ID: 12941630

Title: The muscle integrin binding protein (MIBP) interacts with alpha7beta1 integrin and regulates cell adhesion and laminin matrix deposition.

PubMed ID: 12941630

DOI: 10.1016/s0012-1606(03)00304-x

PubMed ID: 15466886

Title: alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor.

PubMed ID: 15466886

DOI: 10.1242/jcs.01423

PubMed ID: 15181153

Title: NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin.

PubMed ID: 15181153

DOI: 10.1091/mbc.e04-03-0236

PubMed ID: 15734730

Title: Disabled-2 (Dab2) is required for transforming growth factor beta-induced epithelial to mesenchymal transition (EMT).

PubMed ID: 15734730

DOI: 10.1074/jbc.m500974200

PubMed ID: 17947660

Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.

PubMed ID: 17947660

DOI: 10.4049/jimmunol.179.9.5864

PubMed ID: 18804435

Title: Integrin trafficking regulated by Rab21 is necessary for cytokinesis.

PubMed ID: 18804435

DOI: 10.1016/j.devcel.2008.08.001

PubMed ID: 18483218

Title: Kindlin-2 controls bidirectional signaling of integrins.

PubMed ID: 18483218

DOI: 10.1101/gad.469408

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19656770

Title: The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.

PubMed ID: 19656770

DOI: 10.1074/mcp.m900195-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 19903482

Title: c-Abl and Src-family kinases cross-talk in regulation of myeloid cell migration.

PubMed ID: 19903482

DOI: 10.1016/j.febslet.2009.11.009

PubMed ID: 21768292

Title: Osteoblast mineralization requires beta1 integrin/ICAP-1-dependent fibronectin deposition.

PubMed ID: 21768292

DOI: 10.1083/jcb.201007108

PubMed ID: 22654117

Title: Polydom/SVEP1 is a ligand for integrin alpha9beta1.

PubMed ID: 22654117

DOI: 10.1074/jbc.m112.355016

PubMed ID: 28179430

Title: Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.

PubMed ID: 28179430

DOI: 10.1161/circresaha.116.308825

PubMed ID: 34427057

Title: TMEM182 interacts with integrin beta 1 and regulates myoblast differentiation and muscle regeneration.

PubMed ID: 34427057

DOI: 10.1002/jcsm.12767

PubMed ID: 35802072

Title: The integrin ligand SVEP1 regulates GPCR-mediated vasoconstriction via integrins alpha9beta1 and alpha4beta1.

PubMed ID: 35802072

DOI: 10.1111/bph.15921

PubMed ID: 35687021

Title: PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins.

PubMed ID: 35687021

DOI: 10.1083/jcb.202108027

PubMed ID: 36812915

Title: Exercise-activated hepatic autophagy via the FN1-alpha5beta1 integrin pathway drives metabolic benefits of exercise.

PubMed ID: 36812915

DOI: 10.1016/j.cmet.2023.01.011

Sequence Information:

  • Length: 798
  • Mass: 88231
  • Checksum: 26788F7F0A168B56
  • Sequence:
  • MNLQLVSWIG LISLICSVFG QTDKNRCLKA NAKSCGECIQ AGPNCGWCTN TTFLQEGMPT 
    SARCDDLEAL KKKGCQPSDI ENPRGSQTIK KNKNVTNRSK GMAEKLRPED ITQIQPQQLL 
    LKLRSGEPQK FTLKFKRAED YPIDLYYLMD LSYSMKDDLE NVKSLGTDLM NEMRRITSDF 
    RIGFGSFVEK TVMPYISTTP AKLRNPCTSE QNCTSPFSYK NVLSLTDRGE FFNELVGQQR 
    ISGNLDSPEG GFDAIMQVAV CGSLIGWRNV TRLLVFSTDA GFHFAGDGKL GGIVLPNDGQ 
    CHLENNVYTM SHYYDYPSIA HLVQKLSENN IQTIFAVTEE FQPVYKELKN LIPKSAVGTL 
    SGNSSNVIQL IIDAYNSLSS EVILENSKLP DGVTINYKSY CKNGVNGTGE NGRKCSNISI 
    GDEVQFEISI TANKCPNKES ETIKIKPLGF TEEVEVVLQF ICKCNCQSHG IPASPKCHEG 
    NGTFECGACR CNEGRVGRHC ECSTDEVNSE DMDAYCRKEN SSEICSNNGE CVCGQCVCRK 
    RDNTNEIYSG KFCECDNFNC DRSNGLICGG NGVCRCRVCE CYPNYTGSAC DCSLDTGPCL 
    ASNGQICNGR GICECGACKC TDPKFQGPTC ETCQTCLGVC AEHKECVQCR AFNKGEKKDT 
    CAQECSHFNL TKVESREKLP QPVQVDPVTH CKEKDIDDCW FYFTYSVNGN NEAIVHVVET 
    PDCPTGPDII PIVAGVVAGI VLIGLALLLI WKLLMIIHDR REFAKFEKEK MNAKWDTGEN 
    PIYKSAVTTV VNPKYEGK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.