Genular: Defining Cellular Identity and Function

Details for: Itgb1bp1

Gene ID: 16413

Symbol: Itgb1bp1

Ensembl ID: ENSMUSG00000062352

Description: integrin beta 1 binding protein 1

Associated with

Activation of protein kinase b activity
(GO:0032148)
Angiogenesis
(GO:0001525)
Biomineral tissue development
(GO:0031214)
Blood vessel diameter maintenance
(GO:0097746)
Blood vessel endothelial cell proliferation involved in sprouting angiogenesis
(GO:0002043)
Cell-matrix adhesion
(GO:0007160)
Cell adhesion
(GO:0007155)
Cell differentiation
(GO:0030154)
Cell periphery
(GO:0071944)
Cell projection
(GO:0042995)
Cellular response to fibroblast growth factor stimulus
(GO:0044344)
Cellular response to vascular endothelial growth factor stimulus
(GO:0035924)
Centriolar satellite
(GO:0034451)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Cytosol
(GO:0005829)
Gdp-dissociation inhibitor activity
(GO:0005092)
Integrin-mediated signaling pathway
(GO:0007229)
Integrin activation
(GO:0033622)
Integrin binding
(GO:0005178)
Kinase binding
(GO:0019900)
Lamellipodium
(GO:0030027)
Membrane
(GO:0016020)
Myoblast migration
(GO:0051451)
Negative regulation of cell adhesion involved in substrate-bound cell migration
(GO:0006933)
Negative regulation of cell migration involved in sprouting angiogenesis
(GO:0090051)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of erk1 and erk2 cascade
(GO:0070373)
Negative regulation of fibroblast migration
(GO:0010764)
Negative regulation of focal adhesion assembly
(GO:0051895)
Negative regulation of protein binding
(GO:0032091)
Negative regulation of protein kinase activity
(GO:0006469)
Negative regulation of protein targeting to membrane
(GO:0090315)
Negative regulation of substrate adhesion-dependent cell spreading
(GO:1900025)
Notch signaling pathway
(GO:0007219)
Nuclear body
(GO:0016604)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Positive regulation of cell division
(GO:0051781)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of endothelial cell migration
(GO:0010595)
Positive regulation of focal adhesion assembly
(GO:0051894)
Positive regulation of notch signaling pathway
(GO:0045747)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Positive regulation of protein targeting to membrane
(GO:0090314)
Positive regulation of stress fiber assembly
(GO:0051496)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Protein localization to plasma membrane
(GO:0072659)
Receptor clustering
(GO:0043113)
Regulation of cell adhesion
(GO:0030155)
Regulation of cell adhesion mediated by integrin
(GO:0033628)
Regulation of gtpase activity
(GO:0043087)
Regulation of integrin-mediated signaling pathway
(GO:2001044)
Ruffle
(GO:0001726)
Tube formation
(GO:0035148)

Other Information

Proteins

Integrin beta-1-binding protein 1

Genular Protein ID: 3678963934

Symbol: ITBP1_MOUSE

Name: Integrin beta-1-binding protein 1

UniProtKB Accession Codes:

O35671 Q542A8

Database IDs:

Citations:

PubMed ID: 9626504

Title: Bodenin: a novel murine gene expressed in restricted areas of the brain.

PubMed ID: 9626504

DOI: 10.1002/(sici)1097-0177(199806)212:2<293::aid-aja14>3.0.co;2-5

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16741948

Title: Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane.

PubMed ID: 16741948

DOI: 10.1002/jcp.20699

PubMed ID: 17567669

Title: Defective osteoblast function in ICAP-1-deficient mice.

PubMed ID: 17567669

DOI: 10.1242/dev.000877

PubMed ID: 18227284

Title: Cell adaptive response to extracellular matrix density is controlled by ICAP-1-dependent beta1-integrin affinity.

PubMed ID: 18227284

DOI: 10.1083/jcb.200707142

PubMed ID: 17654484

Title: Integrin Cytoplasmic domain-Associated Protein-1 (ICAP-1) promotes migration of myoblasts and affects focal adhesions.

PubMed ID: 17654484

DOI: 10.1002/jcp.21215

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21768292

Title: Osteoblast mineralization requires beta1 integrin/ICAP-1-dependent fibronectin deposition.

PubMed ID: 21768292

DOI: 10.1083/jcb.201007108

Sequence Information:

Length: 200
Mass: 21644
Checksum: F7F0EB09490AEA37
Sequence:

MFRKGKKRHS SSSSQSSEIS TKSKSVDSSL GGLSRSSTVA SLDTDSTKSS GQSNSNLDTC 
AEFRIKYVGA IEKLAVSEGK SLEGPLDLIN YIDVAQQDGK LPFVPLEEEF ILGVSKYGIK 
VSTTDQHGVL HRHALYLIIR MVCYDDGLGA GKSLLALKTT DASNEEYSLW VYQCNSLEQA 
QAICKVLSTA FDSVLTSDKS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Itgb1bp1

Associated with

Other Information

Bodenin: a novel murine gene expressed in restricted areas of the brain. PubMed ID: 9626504

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane. PubMed ID: 16741948

Defective osteoblast function in ICAP-1-deficient mice. PubMed ID: 17567669

Cell adaptive response to extracellular matrix density is controlled by ICAP-1-dependent beta1-integrin affinity. PubMed ID: 18227284

Integrin Cytoplasmic domain-Associated Protein-1 (ICAP-1) promotes migration of myoblasts and affects focal adhesions. PubMed ID: 17654484

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Osteoblast mineralization requires beta1 integrin/ICAP-1-dependent fibronectin deposition. PubMed ID: 21768292