Genular: Defining Cellular Identity and Function

Details for: Itgb6

Gene ID: 16420

Symbol: Itgb6

Ensembl ID: ENSMUSG00000026971

Description: integrin beta 6

Associated with

Ecm proteoglycans
(R-MMU-3000178)
Elastic fibre formation
(R-MMU-1566948)
Extracellular matrix organization
(R-MMU-1474244)
Integrin cell surface interactions
(R-MMU-216083)
Molecules associated with elastic fibres
(R-MMU-2129379)
Signaling by tgf-beta receptor complex
(R-MMU-170834)
Signaling by tgfb family members
(R-MMU-9006936)
Signal transduction
(R-MMU-162582)
Tgf-beta receptor signaling activates smads
(R-MMU-2173789)
Anchoring junction
(GO:0070161)
Bone development
(GO:0060348)
Bronchiole development
(GO:0060435)
Cell-cell adhesion
(GO:0098609)
Cell-matrix adhesion
(GO:0007160)
Cell adhesion
(GO:0007155)
Cell adhesion mediated by integrin
(GO:0033627)
Cell junction
(GO:0030054)
Cell migration
(GO:0016477)
Cell morphogenesis
(GO:0000902)
Cell surface
(GO:0009986)
Cellular response to ionizing radiation
(GO:0071479)
Centrosome
(GO:0005813)
Cytokine production involved in inflammatory response
(GO:0002534)
Enamel mineralization
(GO:0070166)
External side of plasma membrane
(GO:0009897)
Focal adhesion
(GO:0005925)
Gene expression
(GO:0010467)
Hard palate development
(GO:0060022)
Immune response
(GO:0006955)
Inflammatory response
(GO:0006954)
Integrin-mediated signaling pathway
(GO:0007229)
Integrin alphav-beta6 complex
(GO:0034685)
Integrin binding
(GO:0005178)
Langerhans cell differentiation
(GO:0061520)
Lung alveolus development
(GO:0048286)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Nucleoplasm
(GO:0005654)
Phospholipid homeostasis
(GO:0055091)
Plasma membrane
(GO:0005886)
Receptor complex
(GO:0043235)
Regulation of transforming growth factor beta activation
(GO:1901388)
Response to virus
(GO:0009615)
Response to wounding
(GO:0009611)
Skin development
(GO:0043588)
Surfactant homeostasis
(GO:0043129)
Transforming growth factor beta production
(GO:0071604)
Transforming growth factor beta receptor signaling pathway
(GO:0007179)
Wound healing
(GO:0042060)

Other Information

Proteins

Integrin beta-6

Genular Protein ID: 3298536646

Symbol: ITB6_MOUSE

Name: Integrin beta-6

UniProtKB Accession Codes:

Q9Z0T9 Q544J9

Database IDs:

Citations:

PubMed ID: 11095652

Title: Mouse beta(6) integrin sequence, pattern of expression, and role in kidney development.

PubMed ID: 11095652

DOI: 10.1681/asn.v11122297

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 10025398

Title: The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis.

PubMed ID: 10025398

DOI: 10.1016/s0092-8674(00)80545-0

Sequence Information:

Length: 787
Mass: 86042
Checksum: C6438C6F1E6B7FBD
Sequence:

MGIELVCLFL LLLGRNDHVQ GGCAWGGAES CSDCLLTGPH CAWCSQENFT HLSGAGERCD 
TPANLLAKGC QLPFIENPVS RIEVLQNKPL SVGRQKNSSD IVQIAPQSLV LKLRPGREQT 
LQVQVRQTED YPVDLYYLMD LSASMDDDLN TIKELGSRLA KEMSKLTSNF RLGFGSFVEK 
PVSPFMKTTP EEITNPCSSI PYFCLPTFGF KHILPLTDDA ERFNEIVRKQ KISANIDTPE 
GGFDAIMQAA VCKEKIGWRN DSLHLLVFVS DADSHFGMDS KLAGIVIPND GLCHLDHRNE 
YSMSTVLEYP TIGQLIDKLV QNNVLLIFAV TQEQVHLYEN YAKLIPGATV GLLQKDSGNI 
LQLIISAYEE LRSEVELEVL GDTEGLNLSF TALCNNGVLF PHQKKCSHMK VGDTASFNVT 
VSVSNCEKRS RNLIIKPVGL GDTLEILVSA ECDCDCQREI ETNSSKCHNG NGSFQCGVCT 
CNPGHMGPHC ECGEDMVSTD SCKESPGHPS CSGRGDCYCG QCICHLSPYG SIYGPYCQCD 
NFSCLRHKGL LCGDNGDCDC GECVCRDGWT GEYCNCTTNR DSCTSEDGVL CSGRGDCVCG 
KCVCRNPGAS GPTCERCPTC GDPCNSKRSC IECYLSADGQ AQEECADKCK AIGATISEED 
FSKDTSVSCS LQGENECLIT FLITTDNEGK TIIHNINEKD CPKPPNIPMI MLGVSLAILL 
IGVVLLCIWK LLVSFHDRKE VAKFEAERSK AKWQTGTNPL YRGSTSTFKN VTYKHREKHK 
AGLSSDG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Itgb6

Associated with

Other Information

Mouse beta(6) integrin sequence, pattern of expression, and role in kidney development. PubMed ID: 11095652

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334