Genular: Defining Cellular Identity and Function

Details for: Itgb7

Gene ID: 16421

Symbol: Itgb7

Ensembl ID: ENSMUSG00000001281

Description: integrin beta 7

Associated with

Adaptive immune system
(R-MMU-1280218)
Extracellular matrix organization
(R-MMU-1474244)
Immune system
(R-MMU-168256)
Immunoregulatory interactions between a lymphoid and a non-lymphoid cell
(R-MMU-198933)
Integrin cell surface interactions
(R-MMU-216083)
Cell-cell adhesion
(GO:0098609)
Cell-matrix adhesion
(GO:0007160)
Cell-matrix adhesion involved in ameboidal cell migration
(GO:0003366)
Cell adhesion
(GO:0007155)
Cell adhesion mediated by integrin
(GO:0033627)
Cell adhesion molecule binding
(GO:0050839)
Cell surface
(GO:0009986)
Focal adhesion
(GO:0005925)
Heterotypic cell-cell adhesion
(GO:0034113)
Integrin-mediated signaling pathway
(GO:0007229)
Integrin alpha4-beta7 complex
(GO:0034669)
Integrin binding
(GO:0005178)
Integrin complex
(GO:0008305)
Leukocyte migration
(GO:0050900)
Leukocyte tethering or rolling
(GO:0050901)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Plasma membrane
(GO:0005886)
Receptor clustering
(GO:0043113)
Receptor complex
(GO:0043235)
Substrate adhesion-dependent cell spreading
(GO:0034446)
T cell migration
(GO:0072678)

Other Information

Proteins

Integrin beta-7

Genular Protein ID: 2169336427

Symbol: ITB7_MOUSE

Name: Integrin beta-7

UniProtKB Accession Codes:

P26011 Q3U2M1 Q64656

Database IDs:

Citations:

PubMed ID: 1518854

Title: Cloning and expression of mouse integrin beta p(beta 7): a functional role in Peyer's patch-specific lymphocyte homing.

PubMed ID: 1518854

DOI: 10.1073/pnas.89.17.8254

PubMed ID: 1559978

Title: Molecular cloning of the mouse integrin beta 7 subunit.

PubMed ID: 1559978

DOI: 10.1016/s0021-9258(18)42524-0

PubMed ID: 1381390

Title: Expression of murine beta 7, alpha 4, and beta 1 integrin genes by rodent mast cells.

PubMed ID: 1381390

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1710115

Title: Identity between the novel integrin beta 7 subunit and an antigen found highly expressed on intraepithelial lymphocytes in the small intestine.

PubMed ID: 1710115

DOI: 10.1016/0006-291x(91)90448-g

PubMed ID: 8318458

Title: The mouse beta 7 integrin gene promoter: transcriptional regulation of the leukocyte integrins LPAM-1 and M290.

PubMed ID: 8318458

DOI: 10.1093/intimm/5.5.551

Sequence Information:

Length: 806
Mass: 87411
Checksum: E793A3F3BA0B5C18
Sequence:

MVDSSTVLIF LLVLGGGQSE LDTKITSSGE AAEWEDPDLS LQGSCQPVPS CQKCILSHPS 
CAWCKQLNFT ASGEAEARRC ARREELLARG CPAQELEEPR GRQEVLQDKP LSQGDRGEGA 
TQLAPQRIRV TLRPGEPQKF RVRFLRAAGY PVDLYYLMDL SYSMKDDLER VRQLGHALLV 
RLQEVTHSVR IGFGSFVDKT VLPFVSTVPS KLHHPCPSRL ERCQPPFSFH HVLSLTGDAQ 
AFEREVGRQN VSGNLDSPEG GFDAILQAAL CQEQIGWRNV SRLLVFTSDD TFHTAGDGKL 
GGIFMPSDGR CHLDSNGVYT NSAEFDYPSV GQVAQALTAA NIQPIFAVTG ATLPVYQELR 
QLIPKSAVGE LSEDSSNVVQ LIMDAYDSLS STVTLEHSPL PPGVSISFES HCKGPEKTEG 
EAGDRGQCND VRVNQTVDFW VTLQATHCLP EAHVLRLWAL GFSEELTVEL HTVCDCNCGD 
AQPHAPYCSD GQGDLQCGIC SCAPGRLGQL CECSEADLSS PDLESGCRAP NGTGPLCSGK 
GRCQCGRCSC SGQSSGRLCE CDDASCERHE GILCGGFGHC QCGVCHCHAN HTGRACECSK 
SVDSCVSPEG GLCSGHGYCK CNRCQCLDGY YGALCDQCLG CKSPCEQYRD CAECGAFGTG 
PLAANCSVVC ADVNVTLTLA PNLDDGWCKE RTIDNQLFFF LVEHAASGIV LRVRPQEKGV 
DHTRAIILGC TGGIVAVGLG LVLAYRLSVE IYDRREYRRF EKEQQQLNWK QDNNPLYKSA 
ITTTVNPRFQ GTNGRSPSLS LTREAD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Itgb7

Associated with

Other Information

Cloning and expression of mouse integrin beta p(beta 7): a functional role in Peyer's patch-specific lymphocyte homing. PubMed ID: 1518854

Molecular cloning of the mouse integrin beta 7 subunit. PubMed ID: 1559978

Expression of murine beta 7, alpha 4, and beta 1 integrin genes by rodent mast cells. PubMed ID: 1381390

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identity between the novel integrin beta 7 subunit and an antigen found highly expressed on intraepithelial lymphocytes in the small intestine. PubMed ID: 1710115

The mouse beta 7 integrin gene promoter: transcriptional regulation of the leukocyte integrins LPAM-1 and M290. PubMed ID: 8318458