Details for: Itih2

Gene ID: 16425

Symbol: Itih2

Ensembl ID: ENSMUSG00000037254

Description: inter-alpha trypsin inhibitor, heavy chain 2

Associated with

  • Metabolism of proteins
    (R-MMU-392499)
  • Post-translational protein modification
    (R-MMU-597592)
  • Post-translational protein phosphorylation
    (R-MMU-8957275)
  • Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
    (R-MMU-381426)
  • Collagen-containing extracellular matrix
    (GO:0062023)
  • Extracellular region
    (GO:0005576)
  • Hyaluronan metabolic process
    (GO:0030212)
  • Hyaluronic acid binding
    (GO:0005540)
  • Negative regulation of peptidase activity
    (GO:0010466)
  • Peptidase inhibitor activity
    (GO:0030414)
  • Serine-type endopeptidase inhibitor activity
    (GO:0004867)

Other Information

Genular Protein ID: 3764576389

Symbol: ITIH2_MOUSE

Name: Inter-alpha-trypsin inhibitor heavy chain H2

UniProtKB Accession Codes:

Q61703 A2AKU6 Q3UZM0

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CPTAC 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 Ensembl 1 GO 5 Gene3D 1 GeneTree 1 GlyCosmos 1 GlyGen 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PaxDb 1 Pfam 3 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 UniProtKB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 7534067

Title: The three heavy-chain precursors for the inter-alpha-inhibitor family in mouse: new members of the multicopper oxidase protein group with differential transcription in liver and brain.

PubMed ID: 7534067

DOI: 10.1042/bj3060505

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 16944957

Title: Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

PubMed ID: 16944957

DOI: 10.1021/pr060186m

PubMed ID: 17330941

Title: Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides.

PubMed ID: 17330941

DOI: 10.1021/pr0604559

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 946
  • Mass: 105928
  • Checksum: 40DB6716433ED9DC
  • Sequence:
    • MQRPVCLLIW LFLLEAQAFE IPINGNSEFA EYSDLVELAP DKLPFVQENG RHQRSLPEES 
GEETDTVDPV TLYSYKVQST ITSRVATTTI QSKLVNNSPL PQSVVFDVQI PKGAFISNFT 
MTVNGMTFTS SIKEKTVGRA LYSQARAKGK TAGWVRSRTL DMENFNTEVN IPPGAKVQFE 
LHYQEVKWRK LGSYEHKIHL QPGKLAKHLE VNVWIIEPQG MRFLHVPDTF EGHFQGVPVI 
SKGQQKAHVS FKPTVAQQRK CPNCTETAVN GELVVMYDVN REEKAGELEV FNGYFVHFFA 
PENLDPIPKN ILFVIDVSGS MWGIKMKQTV EAMKTILDDL RTDDQFSVVD FNHNVRTWRN 
DLVSATKTQI ADAKRYIEKI QPSGGTNINE ALLRAIFILN EASNMGLLNP DSVSLIILVS 
DGDPTVGELK LSKIQKNVKQ SIQDNISLFS LGIGFDVDYD FLKRLSNENR GIAQRIYGNQ 
DTSSQLKKFY NQVSTPLLRN VQFNYPQASV TDVTQNNFHN YFGGSEIVVA GKFDPSKLTE 
VQSIITATSA NTELVLETLS QMDDLEEFLS KDKHADPDFT KKLWAYLTIN QLLAERSLAP 
TAAIKRKITK TILQMSLDHH IVTPLTAMVI ENDAGDERML ADSPPQDHSC CSGALYYGTK 
VASGPIPSWA NPSPTPMSAM LAVGAKPLES TPPTHLNQVE NDPHFIIYLP KSKRNICFNI 
DSEPGKILSL VSDPESGIVV NGQLIGAKRA ENGKLSTYFG KLGFYFQKEG MKIEISTETI 
TLSSGSSTSR LSWSDTAHLG NSRVLISVKK EKSVTLTLNK ELFFSVLLHR VWRKHPVNVD 
FLGIYAPPID KFSPRVHGLL GQFMQEPAIH IFNERPGKEP GKPEASMEVK GHKLTVTRGL 
QKDYRTDIVF GTDVPCWFVH NSGKGFIDGH YKDYFVPQLY SFLKRP

Genular Protein ID: 3830194036

Symbol: G3X977_MOUSE

Name: N/A

UniProtKB Accession Codes:

G3X977

Database IDs:

AGR 1 ARBA 6 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 HOGENOM 1 InterPro 4 KEGG 1 MGI 2 MaxQB 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 4 PeptideAtlas 1 Pfam 3 PhylomeDB 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 jPOST 1

Citations:

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.M400085-MCP200

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 950
  • Mass: 106361
  • Checksum: BB9AC3513CB69377
  • Sequence:
    • MSSKMQRPVC LLIWLFLLEA QAFEIPINGN SEFAEYSDLV ELAPDKLPFV QENGRHQRSL 
PEESGEETDT VDPVTLYSYK VQSTITSRVA TTTIQSKLVN NSPLPQSVVF DVQIPKGAFI 
SNFTMTVNGM TFTSSIKEKT VGRALYSQAR AKGKTAGWVR SRTLDMENFN TEVNIPPGAK 
VQFELHYQEV KWRKLGSYEH KIHLQPGKLA KHLEVNVWII EPQGMRFLHV PDTFEGHFQG 
VPVISKGQQK AHVSFKPTVA QQRKCPNCTE TAVNGELVVM YDVNREEKAG ELEVFNGYFV 
HFFAPENLDP IPKNILFVID VSGSMWGIKM KQTVEAMKTI LDDLRTDDQF SVVDFNHNVR 
TWRNDLVSAT KTQIADAKRY IEKIQPSGGT NINEALLRAI FILNEASNMG LLNPDSVSLI 
ILVSDGDPTV GELKLSKIQK NVKQSIQDNI SLFSLGIGFD VDYDFLKRLS NENRGIAQRI 
YGNQDTSSQL KKFYNQVSTP LLRNVQFNYP QASVTDVTQN NFHNYFGGSE IVVAGKFDPS 
KLTEVQSIIT ATSANTELVL ETLSQMDDLE EFLSKDKHAD PDFTKKLWAY LTINQLLAER 
SLAPTAAIKR KITKTILQMS LDHHIVTPLT AMVIENDAGD ERMLADSPPQ DHSCCSGALY 
YGTKVASGPI PSWANPSPTP MSAMLAVGAK PLESTPPTHL NQVENDPHFI IYLPKSKRNI 
CFNIDSEPGK ILSLVSDPES GIVVNGQLIG AKRAENGKLS TYFGKLGFYF QKEGMKIEIS 
TETITLSSGS STSRLSWSDT AHLGNSRVLI SVKKEKSVTL TLNKELFFSV LLHRVWRKHP 
VNVDFLGIYA PPIDKFSPRV HGLLGQFMQE PAIHIFNERP GKEPGKPEAS MEVKGHKLTV 
TRGLQKDYRT DIVFGTDVPC WFVHNSGKGF IDGHYKDYFV PQLYSFLKRP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.