Genular: Defining Cellular Identity and Function

Details for: Itln1

Gene ID: 16429

Symbol: Itln1

Ensembl ID: ENSMUSG00000038209

Description: intelectin 1 (galactofuranose binding)

Associated with

Antimicrobial peptides
(R-MMU-6803157)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Brush border membrane
(GO:0031526)
Calcium ion binding
(GO:0005509)
Carbohydrate binding
(GO:0030246)
Collagen-containing extracellular matrix
(GO:0062023)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Membrane raft
(GO:0045121)
Metal ion binding
(GO:0046872)
Oligosaccharide binding
(GO:0070492)
Plasma membrane
(GO:0005886)
Positive regulation of glucose import
(GO:0046326)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein homotrimerization
(GO:0070207)
Receptor complex
(GO:0043235)
Response to nematode
(GO:0009624)
Side of membrane
(GO:0098552)

Other Information

Proteins

Intelectin-1a

Genular Protein ID: 1137257973

Symbol: ITL1A_MOUSE

Name: Intelectin-1a

UniProtKB Accession Codes:

O88310 Q5IWS3

Database IDs:

Citations:

PubMed ID: 9790983

Title: Cloning of the novel gene intelectin, which is expressed in intestinal Paneth cells in mice.

PubMed ID: 9790983

DOI: 10.1006/bbrc.1998.9513

PubMed ID: 14720597

Title: The Xenopus laevis cortical granule lectin: cDNA cloning, developmental expression, and identification of the eglectin family of lectins.

PubMed ID: 14720597

DOI: 10.1016/s1095-6433(03)00269-1

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15222482

Title: Baculovirus expression of mouse lactoferrin receptor and tissue distribution in the mouse.

PubMed ID: 15222482

DOI: 10.1023/b:biom.0000027709.42733.e4

PubMed ID: 15265922

Title: Innate BALB/c enteric epithelial responses to Trichinella spiralis: inducible expression of a novel goblet cell lectin, intelectin-2, and its natural deletion in C57BL/10 mice.

PubMed ID: 15265922

DOI: 10.4049/jimmunol.173.3.1894

PubMed ID: 16936804

Title: Ontogenic changes in lactoferrin receptor and DMT1 in mouse small intestine: implications for iron absorption during early life.

PubMed ID: 16936804

DOI: 10.1139/o06-059

PubMed ID: 16866365

Title: Intelectin: a novel lipid raft-associated protein in the enterocyte brush border.

PubMed ID: 16866365

DOI: 10.1021/bi060570x

PubMed ID: 17420014

Title: Nippostrongylus brasiliensis: identification of intelectin-1 and -2 as Stat6-dependent genes expressed in lung and intestine during infection.

PubMed ID: 17420014

DOI: 10.1016/j.exppara.2007.02.015

PubMed ID: 17621593

Title: Differential structure and activity between human and mouse intelectin-1: human intelectin-1 is a disulfide-linked trimer, whereas mouse homologue is a monomer.

PubMed ID: 17621593

DOI: 10.1093/glycob/cwm075

PubMed ID: 26148048

Title: Recognition of microbial glycans by human intelectin-1.

PubMed ID: 26148048

DOI: 10.1038/nsmb.3053

Sequence Information:

Length: 313
Mass: 34953
Checksum: D2FA447D3D8547A4
Sequence:

MTQLGFLLFI MVATRGCSAA EENLDTNRWG NSFFSSLPRS CKEIKQEHTK AQDGLYFLRT 
KNGVIYQTFC DMTTAGGGWT LVASVHENNM RGKCTVGDRW SSQQGNRADY PEGDGNWANY 
NTFGSAEAAT SDDYKNPGYF DIQAENLGIW HVPNKSPLHN WRKSSLLRYR TFTGFLQHLG 
HNLFGLYKKY PVKYGEGKCW TDNGPALPVV YDFGDARKTA SYYSPSGQRE FTAGYVQFRV 
FNNERAASAL CAGVRVTGCN TEHHCIGGGG FFPEGNPVQC GDFASFDWDG YGTHNGYSSS 
RKITEAAVLL FYR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Itln1

Associated with

Other Information

Cloning of the novel gene intelectin, which is expressed in intestinal Paneth cells in mice. PubMed ID: 9790983

The Xenopus laevis cortical granule lectin: cDNA cloning, developmental expression, and identification of the eglectin family of lectins. PubMed ID: 14720597

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Baculovirus expression of mouse lactoferrin receptor and tissue distribution in the mouse. PubMed ID: 15222482

Innate BALB/c enteric epithelial responses to Trichinella spiralis: inducible expression of a novel goblet cell lectin, intelectin-2, and its natural deletion in C57BL/10 mice. PubMed ID: 15265922

Ontogenic changes in lactoferrin receptor and DMT1 in mouse small intestine: implications for iron absorption during early life. PubMed ID: 16936804

Intelectin: a novel lipid raft-associated protein in the enterocyte brush border. PubMed ID: 16866365

Nippostrongylus brasiliensis: identification of intelectin-1 and -2 as Stat6-dependent genes expressed in lung and intestine during infection. PubMed ID: 17420014

Differential structure and activity between human and mouse intelectin-1: human intelectin-1 is a disulfide-linked trimer, whereas mouse homologue is a monomer. PubMed ID: 17621593

Recognition of microbial glycans by human intelectin-1. PubMed ID: 26148048