Details for: Itpa

Gene ID: 16434

Symbol: Itpa

Ensembl ID: ENSMUSG00000074797

Description: inosine triphosphatase (nucleoside triphosphate pyrophosphatase)

Associated with

Other Information

Genular Protein ID: 3049405260

Symbol: ITPA_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9D892 Q8R0Q8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CPTAC 1 CTD 1 ChEBI 35 ChiTaRS 1 DNASU 1 EC 5 EMBL 2 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 15 Gene3D 1 GeneTree 1 Genevisible 1 HAMAP 1 HAMAP-Rule 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 2 RefSeq 2 Rhea 10 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17090528

Title: Substrate specificity of RdgB protein, a deoxyribonucleoside triphosphate pyrophosphohydrolase.

PubMed ID: 17090528

DOI: 10.1074/jbc.m608708200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20601097

Title: ITPA protein, an enzyme that eliminates deaminated purine nucleoside triphosphates in cells.

PubMed ID: 20601097

DOI: 10.1016/j.mrgentox.2010.06.009

PubMed ID: 20081199

Title: NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals.

PubMed ID: 20081199

DOI: 10.1093/nar/gkp1250

Sequence Information:

  • Length: 198
  • Mass: 21897
  • Checksum: D70337E3D2001A9E
  • Sequence:
    • MAASLVGKKI VFVTGNAKKL EEVIQILGDN FPCTLEAQKI DLPEYQGEPD EISIQKCREA 
ARQVQGPVLV EDTCLCFNAL GGLPGPYIKW FLQKLKPEGL HQLLAGFEDK SAYALCTFAL 
STGDPSQPVL LFRGQTSGQI VMPRGSRDFG WDPCFQPDGY EQTYAEMPKS EKNTISHRFR 
ALHKLQEYFS VAAGAGDH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.