Details for: Kcna1
Associated with
Other Information
Genular Protein ID: 2866072641
Symbol: KCNA1_MOUSE
Name: MKI
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2305265
Title: A family of three mouse potassium channel genes with intronless coding regions.
PubMed ID: 2305265
PubMed ID: 2451788
Title: Cloning of a probable potassium channel gene from mouse brain.
PubMed ID: 2451788
DOI: 10.1038/332837a0
PubMed ID: 8361541
Title: Heteromultimeric K+ channels in terminal and juxtaparanodal regions of neurons.
PubMed ID: 8361541
DOI: 10.1038/365075a0
PubMed ID: 8046438
Title: Localization of Kv1.1 and Kv1.2, two K channel proteins, to synaptic terminals, somata, and dendrites in the mouse brain.
PubMed ID: 8046438
PubMed ID: 7517498
Title: Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
PubMed ID: 7517498
PubMed ID: 8995755
Title: Megencephaly: a new mouse mutation on chromosome 6 that causes hypertrophy of the brain.
PubMed ID: 8995755
PubMed ID: 9736643
Title: Temperature-sensitive neuromuscular transmission in Kv1.1 null mice: role of potassium channels under the myelin sheath in young nerves.
PubMed ID: 9736643
PubMed ID: 9581771
Title: Deletion of the K(V)1.1 potassium channel causes epilepsy in mice.
PubMed ID: 9581771
PubMed ID: 10191303
Title: Specific alteration of spontaneous GABAergic inhibition in cerebellar Purkinje cells in mice lacking the potassium channel Kv1. 1.
PubMed ID: 10191303
PubMed ID: 14686897
Title: Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly.
PubMed ID: 14686897
PubMed ID: 12611922
Title: Hyperexcitability and reduced low threshold potassium currents in auditory neurons of mice lacking the channel subunit Kv1.1.
PubMed ID: 12611922
PubMed ID: 12907802
Title: Nervous system targets of RNA editing identified by comparative genomics.
PubMed ID: 12907802
PubMed ID: 15361858
Title: Control of human potassium channel inactivation by editing of a small mRNA hairpin.
PubMed ID: 15361858
DOI: 10.1038/nsmb825
PubMed ID: 16452087
Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.
PubMed ID: 16452087
PubMed ID: 17250763
Title: Kv1.1 null mice have enlarged hippocampus and ventral cortex.
PubMed ID: 17250763
PubMed ID: 17315199
Title: Lack of potassium channel induces proliferation and survival causing increased neurogenesis and two-fold hippocampus enlargement.
PubMed ID: 17315199
DOI: 10.1002/hipo.20268
PubMed ID: 17917103
Title: Ionic channel function in action potential generation: current perspective.
PubMed ID: 17917103
PubMed ID: 19307729
Title: A missense mutation in the Kv1.1 voltage-gated potassium channel-encoding gene KCNA1 is linked to human autosomal dominant hypomagnesemia.
PubMed ID: 19307729
DOI: 10.1172/jci36948
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 20392939
Title: Kv1.1 potassium channel deficiency reveals brain-driven cardiac dysfunction as a candidate mechanism for sudden unexplained death in epilepsy.
PubMed ID: 20392939
PubMed ID: 21966978
Title: Acoustic startle hypersensitivity in Mceph mice and its effect on hippocampal excitability.
PubMed ID: 21966978
PubMed ID: 21233214
Title: Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow.
PubMed ID: 21233214
PubMed ID: 21483673
Title: Evidence for presence and functional effects of Kv1.1 channels in beta-cells: general survey and results from mceph/mceph mice.
PubMed ID: 21483673
PubMed ID: 22396426
Title: Kcna1 gene deletion lowers the behavioral sensitivity of mice to small changes in sound location and increases asynchronous brainstem auditory evoked potentials but does not affect hearing thresholds.
PubMed ID: 22396426
PubMed ID: 22411008
Title: Kv1.1-dependent control of hippocampal neuron number as revealed by mosaic analysis with double markers.
PubMed ID: 22411008
PubMed ID: 22641786
Title: Transcompartmental reversal of single fibre hyperexcitability in juxtaparanodal Kv1.1-deficient vagus nerve axons by activation of nodal KCNQ channels.
PubMed ID: 22641786
PubMed ID: 22158511
Title: Neuregulin 1 regulates excitability of fast-spiking neurons through Kv1.1 and acts in epilepsy.
PubMed ID: 22158511
DOI: 10.1038/nn.3006
PubMed ID: 23466697
Title: Loss of the Kv1.1 potassium channel promotes pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices.
PubMed ID: 23466697
PubMed ID: 23473320
Title: Kv1.1 channels act as mechanical brake in the senses of touch and pain.
PubMed ID: 23473320
PubMed ID: 25377007
Title: The Kv1.1 null mouse, a model of sudden unexpected death in epilepsy (SUDEP).
PubMed ID: 25377007
DOI: 10.1111/epi.12793
PubMed ID: 23903368
Title: Ankyrin-3 is a novel binding partner of the voltage-gated potassium channel Kv1.1 implicated in renal magnesium handling.
PubMed ID: 23903368
DOI: 10.1038/ki.2013.280
PubMed ID: 26269648
Title: Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing.
PubMed ID: 26269648
Sequence Information:
- Length: 495
- Mass: 56409
- Checksum: C9249F130E943D3D
- Sequence:
MTVMSGENAD EASTAPGHPQ DGSYPRQADH DDHECCERVV INISGLRFET QLKTLAQFPN TLLGNPKKRM RYFDPLRNEY FFDRNRPSFD AILYYYQSGG RLRRPVNVPL DMFSEEIKFY ELGEEAMEKF REDEGFIKEE ERPLPEKEYQ RQVWLLFEYP ESSGPARVIA IVSVMVILIS IVIFCLETLP ELKDDKDFTG TIHRIDNTTV IYTSNIFTDP FFIVETLCII WFSFELVVRF FACPSKTDFF KNIMNFIDIV AIIPYFITLG TEIAEQEGNQ KGEQATSLAI LRVIRLVRVF RIFKLSRHSK GLQILGQTLK ASMRELGLLI FFLFIGVILF SSAVYFAEAE EAESHFSSIP DAFWWAVVSM TTVGYGDMYP VTIGGKIVGS LCAIAGVLTI ALPVPVIVSN FNYFYHRETE GEEQAQLLHV SSPNLASDSD LSRRSSSTIS KSEYMEIEED MNNSIAHYRQ ANIRTGNCTT ADQNCVNKSK LLTDV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.