Genular: Defining Cellular Identity and Function

Details for: Kcna4

Gene ID: 16492

Symbol: Kcna4

Ensembl ID: ENSMUSG00000042604

Description: potassium voltage-gated channel, shaker-related subfamily, member 4

Associated with

Neuronal system
(R-MMU-112316)
Potassium channels
(R-MMU-1296071)
Voltage gated potassium channels
(R-MMU-1296072)
Asymmetric synapse
(GO:0032279)
Axon
(GO:0030424)
Axon initial segment
(GO:0043194)
Cell projection
(GO:0042995)
Cell surface
(GO:0009986)
Delayed rectifier potassium channel activity
(GO:0005251)
Dendritic shaft
(GO:0043198)
Dendritic spine
(GO:0043197)
Glutamatergic synapse
(GO:0098978)
Membrane
(GO:0016020)
Monoatomic ion channel activity
(GO:0005216)
Monoatomic ion channel complex
(GO:0034702)
Monoatomic ion transmembrane transport
(GO:0034220)
Monoatomic ion transport
(GO:0006811)
Plasma membrane
(GO:0005886)
Postsynaptic membrane
(GO:0045211)
Potassium channel activity
(GO:0005267)
Potassium ion binding
(GO:0030955)
Potassium ion transmembrane transport
(GO:0071805)
Potassium ion transport
(GO:0006813)
Presynaptic membrane
(GO:0042734)
Protein binding
(GO:0005515)
Protein homooligomerization
(GO:0051260)
Regulation of presynaptic membrane potential
(GO:0099505)
Transmembrane transport
(GO:0055085)
Voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
(GO:0099508)
Voltage-gated potassium channel activity
(GO:0005249)
Voltage-gated potassium channel complex
(GO:0008076)

Other Information

Proteins

Potassium voltage-gated channel subfamily A member 4

Genular Protein ID: 3209521810

Symbol: KCNA4_MOUSE

Name: Potassium voltage-gated channel subfamily A member 4

UniProtKB Accession Codes:

Q61423 Q8CBF8

Database IDs:

Citations:

PubMed ID: 8020965

Title: Genomic organization, nucleotide sequence, biophysical properties, and localization of the voltage-gated K+ channel gene KCNA4/Kv1.4 to mouse chromosome 2/human 11p14 and mapping of KCNC1/Kv3.1 to mouse 7/human 11p14.3-p15.2 and KCNA1/Kv1.1 to human 12p13.

PubMed ID: 8020965

DOI: 10.1006/geno.1994.1153

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17114649

Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

PubMed ID: 17114649

DOI: 10.1074/mcp.m600046-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 27582084

Title: KCNA4 deficiency leads to a syndrome of abnormal striatum, congenital cataract and intellectual disability.

PubMed ID: 27582084

DOI: 10.1136/jmedgenet-2015-103637

Sequence Information:

Length: 654
Mass: 73470
Checksum: 9322A3DC9CBA2AC4
Sequence:

MEVAMVSAES SGCNSHMPYG YAAQARARER ERLAHSRAAA AAAVAAATAA VEGTGGSGGG 
PHHHHQTRGA YSSHDPQGSR GSRRRRRQRT EKKKLHHRQS SFPHCSDLMP SGSEEKILRE 
LSEEEEDEEE EEEEEEEGRF YYSEEDHGDG CSYTDLLPQD DGGGGGYSSV RYSDCCERVV 
INVSGLRFET QMKTLAQFPE TLLGDPEKRT QYFDPLRNEY FFDRNRPSFD AILYYYQSGG 
RLKRPVNVPF DIFTEEVKFY QLGEEALLKF REDEGFVREE EDRALPENEF KKQIWLLFEY 
PESSSPARGI AIVSVLVILI SIVIFCLETL PEFRDDRDLI MALSAGGHSR LLNDTSAPHL 
ENSGHTIFND PFFIVETVCI VWFSFEFVVR CFACPSQALF FKNIMNIIDI VSILPYFITL 
GTDLAQQQGG GNGQQQQAMS FAILRIIRLV RVFRIFKLSR HSKGLQILGH TLRASMRELG 
LLIFFLFIGV ILFSSAVYFA EADEPTTHFQ SIPDAFWWAV VTMTTVGYGD MKPITVGGKI 
VGSLCAIAGV LTIALPVPVI VSNFNYFYHR ETENEEQTQL TQNAVSCPYL PSNLLKKFRS 
STSSSLGDKS EYLEMEEGVK ESLCGKEEKC QGKGDESETD KNNCSNAKAV ETDV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Kcna4

Associated with

Other Information

Genomic organization, nucleotide sequence, biophysical properties, and localization of the voltage-gated K+ channel gene KCNA4/Kv1.4 to mouse chromosome 2/human 11p14 and mapping of KCNC1/Kv3.1 to mouse 7/human 11p14.3-p15.2 and KCNA1/Kv1.1 to human 12p13. PubMed ID: 8020965

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. PubMed ID: 17114649

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

KCNA4 deficiency leads to a syndrome of abnormal striatum, congenital cataract and intellectual disability. PubMed ID: 27582084