Details for: Kcnd2
Associated with
Other Information
Genular Protein ID: 719245217
Symbol: KCND2_MOUSE
Name: Potassium voltage-gated channel subfamily D member 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12465718
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
PubMed ID: 12465718
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9734479
Title: Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit.
PubMed ID: 9734479
PubMed ID: 10601491
Title: Molecular basis of transient outward K+ current diversity in mouse ventricular myocytes.
PubMed ID: 10601491
PubMed ID: 10818150
Title: A-type K+ current mediated by the Kv4 channel regulates the generation of action potential in developing cerebellar granule cells.
PubMed ID: 10818150
PubMed ID: 11040264
Title: Input-specific immunolocalization of differentially phosphorylated Kv4.2 in the mouse brain.
PubMed ID: 11040264
DOI: 10.1101/lm.35300
PubMed ID: 11606724
Title: A role for frequenin, a Ca2+-binding protein, as a regulator of Kv4 K+-currents.
PubMed ID: 11606724
PubMed ID: 11909823
Title: Role of heteromultimers in the generation of myocardial transient outward K+ currents.
PubMed ID: 11909823
PubMed ID: 16293790
Title: Targeted deletion of Kv4.2 eliminates I(to,f) and results in electrical and molecular remodeling, with no evidence of ventricular hypertrophy or myocardial dysfunction.
PubMed ID: 16293790
PubMed ID: 16009497
Title: Postsynaptic and extrasynaptic localization of Kv4.2 channels in the mouse hippocampal region, with special reference to targeted clustering at gabaergic synapses.
PubMed ID: 16009497
PubMed ID: 17122039
Title: Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons.
PubMed ID: 17122039
PubMed ID: 17122053
Title: Differential expression of I(A) channel subunits Kv4.2 and Kv4.3 in mouse visual cortical neurons and synapses.
PubMed ID: 17122053
PubMed ID: 18045912
Title: Metabotropic glutamate receptor 5 modulates nociceptive plasticity via extracellular signal-regulated kinase-Kv4.2 signaling in spinal cord dorsal horn neurons.
PubMed ID: 18045912
PubMed ID: 17917103
Title: Ionic channel function in action potential generation: current perspective.
PubMed ID: 17917103
PubMed ID: 18187474
Title: Electrical remodelling maintains firing properties in cortical pyramidal neurons lacking KCND2-encoded A-type K+ currents.
PubMed ID: 18187474
PubMed ID: 18357523
PubMed ID: 19713751
Title: Proteomic analyses of native brain K(V)4.2 channel complexes.
PubMed ID: 19713751
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 20371829
Title: Molecular dissection of I(A) in cortical pyramidal neurons reveals three distinct components encoded by Kv4.2, Kv4.3, and Kv1.4 alpha-subunits.
PubMed ID: 20371829
PubMed ID: 20943905
Title: Interdependent roles for accessory KChIP2, KChIP3, and KChIP4 subunits in the generation of Kv4-encoded IA channels in cortical pyramidal neurons.
PubMed ID: 20943905
PubMed ID: 20857488
Title: Spatial learning deficits in mice lacking A-type K(+) channel subunits.
PubMed ID: 20857488
DOI: 10.1002/hipo.20877
PubMed ID: 22738428
Title: Effects of genetic deletion of the Kv4.2 voltage-gated potassium channel on murine anxiety-, fear- and stress-related behaviors.
PubMed ID: 22738428
PubMed ID: 22612819
Title: The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice.
PubMed ID: 22612819
PubMed ID: 22098631
Title: Unique somato-dendritic distribution pattern of Kv4.2 channels on hippocampal CA1 pyramidal cells.
PubMed ID: 22098631
PubMed ID: 22311982
Title: Augmentation of Kv4.2-encoded currents by accessory dipeptidyl peptidase 6 and 10 subunits reflects selective cell surface Kv4.2 protein stabilization.
PubMed ID: 22311982
PubMed ID: 22815518
Title: I(A) channels encoded by Kv1.4 and Kv4.2 regulate neuronal firing in the suprachiasmatic nucleus and circadian rhythms in locomotor activity.
PubMed ID: 22815518
PubMed ID: 23713033
Title: Stabilization of Kv4 protein by the accessory K(+) channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K(+) currents.
PubMed ID: 23713033
Sequence Information:
- Length: 630
- Mass: 70577
- Checksum: 7FB94277429E7683
- Sequence:
MAAGVAAWLP FARAAAIGWM PVASGPMPAP PRQERKRTQD ALIVLNVSGT RFQTWQDTLE RYPDTLLGSS ERDFFYHPET QQYFFDRDPD IFRHILNFYR TGKLHYPRHE CISAYDEELA FFGLIPEIIG DCCYEEYKDR RRENAERLQD DADTDNTGES ALPTMTARQR VWRAFENPHT STMALVFYYV TGFFIAVSVI ANVVETVPCG SSPGHIKELP CGERYAVAFF CLDTACVMIF TVEYLLRLAA APSRYRFVRS VMSIIDVVAI LPYYIGLVMT DNEDVSGAFV TLRVFRVFRI FKFSRHSQGL RILGYTLKSC ASELGFLLFS LTMAIIIFAT VMFYAEKGSS ASKFTSIPAA FWYTIVTMTT LGYGDMVPKT IAGKIFGSIC SLSGVLVIAL PVPVIVSNFS RIYHQNQRAD KRRAQKKARL ARIRAAKSGS ANAYMQSKRN GLLSNQLQSS EDEPAFISKS GSSFETQHHH LLHCLEKTTN HEFVDEQVFE ESCMEVATVN RPSSHSPSLS SQQGVTSTCC SRRHKKTFRI PNANVSGSHR GSVQELSTIQ IRCVERTPLS NSRSSLNAKM EECVKLNCEQ PYVTTAIISI PTPPVTTPEG DDRPESPEYS GGNIVRVSAL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.