Genular: Defining Cellular Identity and Function

Details for: Kcnj2

Gene ID: 16518

Symbol: Kcnj2

Ensembl ID: ENSMUSG00000041695

Description: potassium inwardly-rectifying channel, subfamily J, member 2

Associated with

Activation of gabab receptors
(R-MMU-991365)
Activation of g protein gated potassium channels
(R-MMU-1296041)
Cardiac conduction
(R-MMU-5576891)
Classical kir channels
(R-MMU-1296053)
Gaba b receptor activation
(R-MMU-977444)
Gaba receptor activation
(R-MMU-977443)
G protein gated potassium channels
(R-MMU-1296059)
Inhibition of voltage gated ca2+ channels via gbeta/gamma subunits
(R-MMU-997272)
Inwardly rectifying k+ channels
(R-MMU-1296065)
Muscle contraction
(R-MMU-397014)
Neuronal system
(R-MMU-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-MMU-112314)
Phase 4 - resting membrane potential
(R-MMU-5576886)
Potassium channels
(R-MMU-1296071)
Transmission across chemical synapses
(R-MMU-112315)
Cardiac muscle cell action potential
(GO:0086001)
Cardiac muscle cell action potential involved in contraction
(GO:0086002)
Dendrite
(GO:0030425)
Dendritic spine
(GO:0043197)
Glutamatergic synapse
(GO:0098978)
Identical protein binding
(GO:0042802)
Intercalated disc
(GO:0014704)
Inward rectifier potassium channel activity
(GO:0005242)
Magnesium ion transport
(GO:0015693)
Membrane
(GO:0016020)
Membrane repolarization during action potential
(GO:0086011)
Membrane repolarization during cardiac muscle cell action potential
(GO:0086013)
Monoatomic ion channel complex
(GO:0034702)
Monoatomic ion transmembrane transport
(GO:0034220)
Monoatomic ion transport
(GO:0006811)
Neuronal cell body
(GO:0043025)
Phosphatidylinositol-4,5-bisphosphate binding
(GO:0005546)
Plasma membrane
(GO:0005886)
Positive regulation of potassium ion transmembrane transport
(GO:1901381)
Postsynaptic membrane
(GO:0045211)
Potassium ion import across plasma membrane
(GO:1990573)
Potassium ion transmembrane transport
(GO:0071805)
Potassium ion transport
(GO:0006813)
Protein binding
(GO:0005515)
Protein homotetramerization
(GO:0051289)
Regulation of cardiac muscle cell contraction
(GO:0086004)
Regulation of heart rate by cardiac conduction
(GO:0086091)
Regulation of membrane repolarization
(GO:0060306)
Regulation of monoatomic ion transmembrane transport
(GO:0034765)
Regulation of skeletal muscle contraction via regulation of action potential
(GO:0014861)
Relaxation of cardiac muscle
(GO:0055119)
Relaxation of skeletal muscle
(GO:0090076)
T-tubule
(GO:0030315)
Voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
(GO:0086008)
Voltage-gated potassium channel complex
(GO:0008076)

Other Information

Proteins

Inward rectifier potassium channel 2

Genular Protein ID: 1402693381

Symbol: KCNJ2_MOUSE

Name: Inward rectifier potassium channel 2

UniProtKB Accession Codes:

P35561

Database IDs:

Citations:

PubMed ID: 7680768

Title: Primary structure and functional expression of a mouse inward rectifier potassium channel.

PubMed ID: 7680768

DOI: 10.1038/362127a0

PubMed ID: 8282096

Title: Molecular cloning, functional expression and localization of an inward rectifier potassium channel in the mouse brain.

PubMed ID: 8282096

DOI: 10.1016/0014-5793(93)80840-q

PubMed ID: 9533862

Title: Inwardly rectifying potassium channels in lens epithelium are from the IRK1 (Kir 2.1) family.

PubMed ID: 9533862

DOI: 10.1006/exer.1997.0432

PubMed ID: 16571646

Title: Functional and clinical characterization of a mutation in KCNJ2 associated with Andersen-Tawil syndrome.

PubMed ID: 16571646

DOI: 10.1136/jmg.2006.040816

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

Sequence Information:

Length: 428
Mass: 48389
Checksum: 5B4219F979BBA41C
Sequence:

MGSVRTNRYS IVSSEEDGMK LATMAVANGF GNGKSKVHTR QQCRSRFVKK DGHCNVQFIN 
VGEKGQRYLA DIFTTCVDIR WRWMLVIFCL AFVLSWLFFG CVFWLIALLH GDLDTSKVSK 
ACVSEVNSFT AAFLFSIETQ TTIGYGFRCV TDECPIAVFM VVFQSIVGCI IDAFIIGAVM 
AKMAKPKKRN ETLVFSHNAV IAMRDGKLCL MWRVGNLRKS HLVEAHVRAQ LLKSRITSEG 
EYIPLDQIDI NVGFDSGIDR IFLVSPITIV HEIDEDSPLY DLSKQDIDNA DFEIVVILEG 
MVEATAMTTQ CRSSYLANEI LWGHRYEPVL FEEKHYYKVD YSRFHKTYEV PNTPLCSARD 
LAEKKYILSN ANSFCYENEV ALTSKEEEED SENGVPESTS TDSPPGIDLH NQASVPLEPR 
PLRRESEI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Kcnj2

Associated with

Other Information

Primary structure and functional expression of a mouse inward rectifier potassium channel. PubMed ID: 7680768

Molecular cloning, functional expression and localization of an inward rectifier potassium channel in the mouse brain. PubMed ID: 8282096

Inwardly rectifying potassium channels in lens epithelium are from the IRK1 (Kir 2.1) family. PubMed ID: 9533862