Genular: Defining Cellular Identity and Function

Details for: Kcnn4

Gene ID: 16534

Symbol: Kcnn4

Ensembl ID: ENSMUSG00000054342

Description: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

Associated with

Ca2+ activated k+ channels
(R-MMU-1296052)
Neuronal system
(R-MMU-112316)
Potassium channels
(R-MMU-1296071)
Apical plasma membrane
(GO:0016324)
Basolateral plasma membrane
(GO:0016323)
Calcium-activated potassium channel activity
(GO:0015269)
Calcium ion transport
(GO:0006816)
Calmodulin binding
(GO:0005516)
Cardiac muscle hypertrophy
(GO:0003300)
Cell volume homeostasis
(GO:0006884)
Cytosol
(GO:0005829)
Establishment of localization in cell
(GO:0051649)
Hepatocyte apoptotic process
(GO:0097284)
Immune system process
(GO:0002376)
Intermediate conductance calcium-activated potassium channel activity
(GO:0022894)
Inward rectifier potassium channel activity
(GO:0005242)
Membrane
(GO:0016020)
Monoatomic anion transport
(GO:0006820)
Monoatomic ion transmembrane transport
(GO:0034220)
Monoatomic ion transport
(GO:0006811)
Mononuclear cell migration
(GO:0071674)
Negative regulation of cardiac muscle hypertrophy
(GO:0010614)
Negative regulation of cell volume
(GO:0045794)
Negative regulation of hepatic stellate cell proliferation
(GO:1904898)
Neuronal cell body
(GO:0043025)
Neuron projection
(GO:0043005)
Phospholipid translocation
(GO:0045332)
Plasma membrane
(GO:0005886)
Positive regulation of g0 to g1 transition
(GO:0070318)
Positive regulation of microglial cell activation
(GO:1903980)
Positive regulation of p38mapk cascade
(GO:1900745)
Positive regulation of protein secretion
(GO:0050714)
Positive regulation of smooth muscle cell proliferation
(GO:0048661)
Positive regulation of t cell receptor signaling pathway
(GO:0050862)
Potassium channel activity
(GO:0005267)
Potassium ion export across plasma membrane
(GO:0097623)
Potassium ion transmembrane transport
(GO:0071805)
Potassium ion transport
(GO:0006813)
Protein phosphatase binding
(GO:0019903)
Regulation of angiotensin levels in blood
(GO:0002002)
Regulation of monocyte chemotactic protein-1 production
(GO:0071637)
Regulation of renin secretion into blood stream
(GO:1900133)
Regulation of smooth muscle cell proliferation
(GO:0048660)
Regulation of tumor necrosis factor production
(GO:0032680)
Saliva secretion
(GO:0046541)
Small conductance calcium-activated potassium channel activity
(GO:0016286)
Stabilization of membrane potential
(GO:0030322)
Vascular associated smooth muscle cell migration
(GO:1904738)
Vesicle
(GO:0031982)

Other Information

Proteins

Intermediate conductance calcium-activated potassium channel protein 4

Genular Protein ID: 1698936220

Symbol: KCNN4_MOUSE

Name: Intermediate conductance calcium-activated potassium channel protein 4

UniProtKB Accession Codes:

O89109 Q3U1J8 Q9CY39

Database IDs:

Citations:

PubMed ID: 9705284

Title: cDNA cloning and functional characterization of the mouse Ca2+-gated K+ channel, mIK1. Roles in regulatory volume decrease and erythroid differentiation.

PubMed ID: 9705284

DOI: 10.1074/jbc.273.34.21542

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 20884616

Title: Nucleoside diphosphate kinase B knock-out mice have impaired activation of the K+ channel KCa3.1, resulting in defective T cell activation.

PubMed ID: 20884616

DOI: 10.1074/jbc.m110.168070

Sequence Information:

Length: 425
Mass: 47784
Checksum: DCD2FC86BDD69A73
Sequence:

MGGELVTGLG ALRRRKRLLE QEKRVAGWAL VLAGTGIGLM VLHAEMLWFL GCKWVLYLLL 
VKCLITLSTA FLLCLIVVFH AKEVQLFMTD NGLRDWRVAL TRRQVAQILL ELLVCGVHPV 
PLRSPHCALA GEATDAQPWP GFLGEGEALL SLAMLLRLYL VPRAVLLRSG VLLNASYRSI 
GALNQVRFRH WFVAKLYMNT HPGRLLLGLT LGLWLTTAWV LSVAERQAVN ATGHLTDTLW 
LIPITFLTIG YGDVVPGTMW GKIVCLCTGV MGVCCTALLV AVVARKLEFN KAEKHVHNFM 
MDIHYAKEMK ESAARLLQEA WMYYKHTRRK DSRAARRHQR KMLAAIHTFR QVRLKHRKLR 
EQVNSMVDIS KMHMILCDLQ LGLSSSHRAL EKRIDGLAGK LDALTELLGT ALQQQQLPEP 
SQEAT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Kcnn4

Associated with

Other Information

cDNA cloning and functional characterization of the mouse Ca2+-gated K+ channel, mIK1. Roles in regulatory volume decrease and erythroid differentiation. PubMed ID: 9705284

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Nucleoside diphosphate kinase B knock-out mice have impaired activation of the K+ channel KCa3.1, resulting in defective T cell activation. PubMed ID: 20884616

Database document:

PubMed ID: 9705284

PubMed ID: 16141072

PubMed ID: 15489334

PubMed ID: 20884616