Details for: Kit
Associated with
Other Information
Genular Protein ID: 3455520726
Symbol: KIT_MOUSE
Name: Mast/stem cell growth factor receptor Kit
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2456920
Title: Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family -- oncogenic activation of v-kit involves deletion of extracellular domain and C-terminus.
PubMed ID: 2456920
PubMed ID: 1709486
Title: Exon skipping by mutation of an authentic splice site of c-kit gene in W/W mouse.
PubMed ID: 1709486
PubMed ID: 1378413
Title: A novel c-kit transcript, potentially encoding a truncated receptor, originates within a kit gene intron in mouse spermatids.
PubMed ID: 1378413
PubMed ID: 15731517
Title: Identification of a novel point mutation of mouse proto-oncogene c-kit through N-ethyl-N-nitrosourea mutagenesis.
PubMed ID: 15731517
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7682073
Title: Cloning and functional analysis of the mouse c-kit promoter.
PubMed ID: 7682073
PubMed ID: 1698611
Title: Candidate ligand for the c-kit transmembrane kinase receptor: KL, a fibroblast derived growth factor stimulates mast cells and erythroid progenitors.
PubMed ID: 1698611
PubMed ID: 1714377
Title: Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase.
PubMed ID: 1714377
PubMed ID: 7509796
Title: Tyrosine residue 719 of the c-kit receptor is essential for binding of the P85 subunit of phosphatidylinositol (PI) 3-kinase and for c-kit-associated PI 3-kinase activity in COS-1 cells.
PubMed ID: 7509796
PubMed ID: 7527401
Title: Mechanism of down-regulation of c-kit receptor. Roles of receptor tyrosine kinase, phosphatidylinositol 3'-kinase, and protein kinase C.
PubMed ID: 7527401
PubMed ID: 9722617
Title: Involvement of phospholipase Cgamma1 in mouse egg activation induced by a truncated form of the C-kit tyrosine kinase present in spermatozoa.
PubMed ID: 9722617
PubMed ID: 9528781
Title: SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain.
PubMed ID: 9528781
PubMed ID: 12558531
Title: Molecular mechanisms utilized by alternative c-kit gene products in the control of spermatogonial proliferation and sperm-mediated egg activation.
PubMed ID: 12558531
PubMed ID: 17595334
Title: The tyrosine kinase FES is an essential effector of KITD816V proliferation signal.
PubMed ID: 17595334
PubMed ID: 17947660
Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.
PubMed ID: 17947660
PubMed ID: 18725415
Title: Protein-tyrosine phosphatase alpha regulates stem cell factor-dependent c-Kit activation and migration of mast cells.
PubMed ID: 18725415
PubMed ID: 18447649
Title: Murine hematopoietic stem cells and multipotent progenitors express truncated intracellular form of c-kit receptor.
PubMed ID: 18447649
PubMed ID: 21037083
Title: Nf1-/- Schwann cell-conditioned medium modulates mast cell degranulation by c-Kit-mediated hyperactivation of phosphatidylinositol 3-kinase.
PubMed ID: 21037083
PubMed ID: 20200353
Title: The receptor tyrosine kinase c-Kit controls IL-33 receptor signaling in mast cells.
PubMed ID: 20200353
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 17255936
Title: Structural basis for stem cell factor-KIT signaling and activation of class III receptor tyrosine kinases.
PubMed ID: 17255936
PubMed ID: 1688471
Title: The dominant W42 spotting phenotype results from a missense mutation in the c-kit receptor kinase.
PubMed ID: 1688471
PubMed ID: 1693331
Title: Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W.
PubMed ID: 1693331
Sequence Information:
- Length: 979
- Mass: 109343
- Checksum: 03FB4D672248585E
- Sequence:
MRGARGAWDL LCVLLVLLRG QTATSQPSAS PGEPSPPSIH PAQSELIVEA GDTLSLTCID PDFVRWTFKT YFNEMVENKK NEWIQEKAEA TRTGTYTCSN SNGLTSSIYV FVRDPAKLFL VGLPLFGKED SDALVRCPLT DPQVSNYSLI ECDGKSLPTD LTFVPNPKAG ITIKNVKRAY HRLCVRCAAQ RDGTWLHSDK FTLKVRAAIK AIPVVSVPET SHLLKKGDTF TVVCTIKDVS TSVNSMWLKM NPQPQHIAQV KHNSWHRGDF NYERQETLTI SSARVDDSGV FMCYANNTFG SANVTTTLKV VEKGFINISP VKNTTVFVTD GENVDLVVEY EAYPKPEHQQ WIYMNRTSAN KGKDYVKSDN KSNIRYVNQL RLTRLKGTEG GTYTFLVSNS DASASVTFNV YVNTKPEILT YDRLINGMLQ CVAEGFPEPT IDWYFCTGAE QRCTTPVSPV DVQVQNVSVS PFGKLVVQSS IDSSVFRHNG TVECKASNDV GKSSAFFNFA FKGNNKEQIQ AHTLFTPLLI GFVVAAGAMG IIVMVLTYKY LQKPMYEVQW KVVEEINGNN YVYIDPTQLP YDHKWEFPRN RLSFGKTLGA GAFGKVVEAT AYGLIKSDAA MTVAVKMLKP SAHLTEREAL MSELKVLSYL GNHMNIVNLL GACTVGGPTL VITEYCCYGD LLNFLRRKRD SFIFSKQEEQ AEAALYKNLL HSTEPSCDSS NEYMDMKPGV SYVVPTKTDK RRSARIDSYI ERDVTPAIME DDELALDLDD LLSFSYQVAK GMAFLASKNC IHRDLAARNI LLTHGRITKI CDFGLARDIR NDSNYVVKGN ARLPVKWMAP ESIFSCVYTF ESDVWSYGIF LWELFSLGSS PYPGMPVDSK FYKMIKEGFR MVSPEHAPAE MYDVMKTCWD ADPLKRPTFK QVVQLIEKQI SDSTKHIYSN LANCNPNPEN PVVVDHSVRV NSVGSSASST QPLLVHEDA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.