Genular: Defining Cellular Identity and Function

Details for: Kpna1

Gene ID: 16646

Symbol: Kpna1

Ensembl ID: ENSMUSG00000022905

Description: karyopherin subunit alpha 1

Associated with

Apoptosis
(R-MMU-109581)
Apoptosis induced dna fragmentation
(R-MMU-140342)
Apoptotic execution phase
(R-MMU-75153)
Assembly of the orc complex at the origin of replication
(R-MMU-68616)
Assembly of the pre-replicative complex
(R-MMU-68867)
Cytokine signaling in immune system
(R-MMU-1280215)
Dna replication
(R-MMU-69306)
Dna replication pre-initiation
(R-MMU-69002)
Immune system
(R-MMU-168256)
Interferon alpha/beta signaling
(R-MMU-909733)
Interferon signaling
(R-MMU-913531)
Programmed cell death
(R-MMU-5357801)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dendrite
(GO:0030425)
Glutamatergic synapse
(GO:0098978)
Nls-bearing protein import into nucleus
(GO:0006607)
Nls-dependent protein nuclear import complex
(GO:0042564)
Nuclear import signal receptor activity
(GO:0061608)
Nuclear localization sequence binding
(GO:0008139)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Postsynapse to nucleus signaling pathway
(GO:0099527)
Postsynaptic density
(GO:0014069)
Protein binding
(GO:0005515)
Protein import into nucleus
(GO:0006606)
Protein transport
(GO:0015031)
Regulation of apoptotic process
(GO:0042981)
Regulation of canonical wnt signaling pathway
(GO:0060828)
Satellite cell activation involved in skeletal muscle regeneration
(GO:0014901)
Skeletal muscle satellite cell proliferation
(GO:0014841)
Skeletal muscle tissue regeneration
(GO:0043403)

Other Information

Proteins

Importin subunit alpha-5

Genular Protein ID: 722564579

Symbol: IMA5_MOUSE

Name: Importin subunit alpha-5

UniProtKB Accession Codes:

Q60960 Q3TF32

Database IDs:

Citations:

PubMed ID: 8631802

Title: The nuclear localization signal of lymphoid enhancer factor-1 is recognized by two differentially expressed Srp1-nuclear localization sequence receptor proteins.

PubMed ID: 8631802

DOI: 10.1074/jbc.271.13.7654

PubMed ID: 9369227

Title: Identification of novel homologues of mouse importin alpha, the alpha subunit of the nuclear pore-targeting complex, and their tissue-specific expression.

PubMed ID: 9369227

DOI: 10.1016/s0014-5793(97)01092-2

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8052633

Title: RAG-1 interacts with the repeated amino acid motif of the human homologue of the yeast protein SRP1.

PubMed ID: 8052633

DOI: 10.1073/pnas.91.16.7633

PubMed ID: 10692581

Title: Characterization of the nuclear transport of a novel leucine-rich acidic nuclear protein-like protein.

PubMed ID: 10692581

DOI: 10.1016/s0014-5793(00)01218-7

PubMed ID: 18716025

Title: Functional and structural basis of the nuclear localization signal in the ZIC3 zinc finger domain.

PubMed ID: 18716025

DOI: 10.1093/hmg/ddn239

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 27703206

Title: Two isoforms of TALDO1 generated by alternative translational initiation show differential nucleocytoplasmic distribution to regulate the global metabolic network.

PubMed ID: 27703206

DOI: 10.1038/srep34648

PubMed ID: 29599122

Title: Intersectin goes nuclear: secret life of an endocytic protein.

PubMed ID: 29599122

DOI: 10.1042/bcj20170897

Sequence Information:

Length: 538
Mass: 60183
Checksum: 8FE16ACA99F2BA4F
Sequence:

MSTPGKENFR LKSYKNKSLN PDEMRRRREE EGLQLRKQKR EEQLFKRRNV ATAEEETEEE 
VMSDGGFHEA QINNMEMAPG GVITSDMTDM IFSNSPEQQL SATQKFRKLL SKEPNPPIDE 
VINTPGVVAR FVEFLKRKEN CTLQFESAWV LTNIASGNSL QTRNVIQAGA VPIFIELLSS 
EFEDVQEQAV WALGNIAGDS TMCRDYVLNC NILPPLLQLF SKQNRLTMTR NAVWALSNLC 
RGKSPPPEFA KVSPCLNVLS WLLFVSDTDV LADACWALSY LSDGPNDKIQ AVIDAGVCRR 
LVELLMHNDY KVVSPALRAV GNIVTGDDIQ TQVILNCSAL QSLLHLLSSP KESIKKEACW 
TISNITAGNR AQIQTVIDAN MFPALISILQ TAEFRTRKEA AWAITNATSG GSAEQIKYLV 
ELGCIKPLCD LLTVMDAKIV QVALNGLENI LRLGEQEAKR NGSGINPYCA LIEEAYGLDK 
IEFLQSHENQ EIYQKAFDLI EHYFGTEDED SSIAPQVDLS QQQYIFQQCE APMEGFQL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Kpna1

Associated with

Other Information

The nuclear localization signal of lymphoid enhancer factor-1 is recognized by two differentially expressed Srp1-nuclear localization sequence receptor proteins. PubMed ID: 8631802

Identification of novel homologues of mouse importin alpha, the alpha subunit of the nuclear pore-targeting complex, and their tissue-specific expression. PubMed ID: 9369227

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

RAG-1 interacts with the repeated amino acid motif of the human homologue of the yeast protein SRP1. PubMed ID: 8052633

Characterization of the nuclear transport of a novel leucine-rich acidic nuclear protein-like protein. PubMed ID: 10692581

Functional and structural basis of the nuclear localization signal in the ZIC3 zinc finger domain. PubMed ID: 18716025

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Two isoforms of TALDO1 generated by alternative translational initiation show differential nucleocytoplasmic distribution to regulate the global metabolic network. PubMed ID: 27703206

Intersectin goes nuclear: secret life of an endocytic protein. PubMed ID: 29599122