Genular: Defining Cellular Identity and Function

Details for: Kras

Gene ID: 16653

Symbol: Kras

Ensembl ID: ENSMUSG00000030265

Description: Kirsten rat sarcoma viral oncogene homolog

Associated with

Activation of ras in b cells
(R-MMU-1169092)
Adaptive immune system
(R-MMU-1280218)
Axon guidance
(R-MMU-422475)
Beta-catenin independent wnt signaling
(R-MMU-3858494)
C-type lectin receptors (clrs)
(R-MMU-5621481)
Ca2+ pathway
(R-MMU-4086398)
Cd209 (dc-sign) signaling
(R-MMU-5621575)
Cell surface interactions at the vascular wall
(R-MMU-202733)
Cytokine signaling in immune system
(R-MMU-1280215)
Dap12 interactions
(R-MMU-2172127)
Dap12 signaling
(R-MMU-2424491)
Developmental biology
(R-MMU-1266738)
Downstream signaling events of b cell receptor (bcr)
(R-MMU-1168372)
Downstream signaling of activated fgfr1
(R-MMU-5654687)
Downstream signaling of activated fgfr2
(R-MMU-5654696)
Downstream signaling of activated fgfr3
(R-MMU-5654708)
Downstream signaling of activated fgfr4
(R-MMU-5654716)
Downstream signal transduction
(R-MMU-186763)
Egfr transactivation by gastrin
(R-MMU-2179392)
Esr-mediated signaling
(R-MMU-8939211)
Estrogen-stimulated signaling through prkcz
(R-MMU-9634635)
Extra-nuclear estrogen signaling
(R-MMU-9009391)
Fc epsilon receptor (fceri) signaling
(R-MMU-2454202)
Fceri mediated mapk activation
(R-MMU-2871796)
Flt3 signaling
(R-MMU-9607240)
Frs-mediated fgfr1 signaling
(R-MMU-5654693)
Frs-mediated fgfr2 signaling
(R-MMU-5654700)
Frs-mediated fgfr3 signaling
(R-MMU-5654706)
Frs-mediated fgfr4 signaling
(R-MMU-5654712)
G alpha (q) signalling events
(R-MMU-416476)
Gastrin-creb signalling pathway via pkc and mapk
(R-MMU-881907)
Gpcr downstream signalling
(R-MMU-388396)
Grb2 events in egfr signaling
(R-MMU-179812)
Grb2 events in erbb2 signaling
(R-MMU-1963640)
Hemostasis
(R-MMU-109582)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Map2k and mapk activation
(R-MMU-5674135)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Met activates ras signaling
(R-MMU-8851805)
Ncam signaling for neurite out-growth
(R-MMU-375165)
Negative regulation of mapk pathway
(R-MMU-5675221)
Nervous system development
(R-MMU-9675108)
P38mapk events
(R-MMU-171007)
Ptk6 regulates rho gtpases, ras gtpase and map kinases
(R-MMU-8849471)
Raf/map kinase cascade
(R-MMU-5673001)
Raf activation
(R-MMU-5673000)
Ras processing
(R-MMU-9648002)
Regulation of ras by gaps
(R-MMU-5658442)
Shc-mediated cascade:fgfr1
(R-MMU-5654688)
Shc-mediated cascade:fgfr2
(R-MMU-5654699)
Shc-mediated cascade:fgfr3
(R-MMU-5654704)
Shc-mediated cascade:fgfr4
(R-MMU-5654719)
Shc1 events in egfr signaling
(R-MMU-180336)
Shc1 events in erbb4 signaling
(R-MMU-1250347)
Signaling by csf3 (g-csf)
(R-MMU-9674555)
Signaling by egfr
(R-MMU-177929)
Signaling by erbb2
(R-MMU-1227986)
Signaling by erbb4
(R-MMU-1236394)
Signaling by fgfr
(R-MMU-190236)
Signaling by fgfr1
(R-MMU-5654736)
Signaling by fgfr2
(R-MMU-5654738)
Signaling by fgfr3
(R-MMU-5654741)
Signaling by fgfr4
(R-MMU-5654743)
Signaling by gpcr
(R-MMU-372790)
Signaling by met
(R-MMU-6806834)
Signaling by non-receptor tyrosine kinases
(R-MMU-9006927)
Signaling by ntrk1 (trka)
(R-MMU-187037)
Signaling by ntrks
(R-MMU-166520)
Signaling by nuclear receptors
(R-MMU-9006931)
Signaling by pdgf
(R-MMU-186797)
Signaling by ptk6
(R-MMU-8848021)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by scf-kit
(R-MMU-1433557)
Signaling by the b cell receptor (bcr)
(R-MMU-983705)
Signaling by vegf
(R-MMU-194138)
Signaling by wnt
(R-MMU-195721)
Signalling to erks
(R-MMU-187687)
Signalling to ras
(R-MMU-167044)
Tie2 signaling
(R-MMU-210993)
Vegfa-vegfr2 pathway
(R-MMU-4420097)
Vegfr2 mediated cell proliferation
(R-MMU-5218921)
Gdp binding
(GO:0019003)
Gmp binding
(GO:0019002)
G protein activity
(GO:0003925)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Hydrolase activity
(GO:0016787)
Identical protein binding
(GO:0042802)
Lrr domain binding
(GO:0030275)
Nucleotide binding
(GO:0000166)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein-containing complex binding
(GO:0044877)
Protein-membrane adaptor activity
(GO:0043495)
Protein binding
(GO:0005515)
Signal transduction
(GO:0007165)

Other Information

Proteins

GTPase KRas
Q5J7N1_MOUSE

Genular Protein ID: 590703103

Symbol: RASK_MOUSE

Name: GTPase KRas

UniProtKB Accession Codes:

P32883 P04200 P08643

Database IDs:

Citations:

PubMed ID: 4006913

Title: Structure and expression of amplified cKi-ras gene sequences in Y1 mouse adrenal tumor cells.

PubMed ID: 4006913

DOI: 10.1002/j.1460-2075.1985.tb03760.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6474169

Title: Activation of a c-K-ras oncogene by somatic mutation in mouse lymphomas induced by gamma radiation.

PubMed ID: 6474169

DOI: 10.1126/science.6474169

PubMed ID: 1352876

Title: Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids.

PubMed ID: 1352876

DOI: 10.1073/pnas.89.13.5804

PubMed ID: 6546797

Title: Amplified DNA in Y1 mouse adrenal tumor cells: isolation of cDNAs complementary to an amplified c-Ki-ras gene and localization of homologous sequences to mouse chromosome 6.

PubMed ID: 6546797

DOI: 10.1093/nar/12.6.2731

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 189
Mass: 21656
Checksum: 97345422E01D2C81
Sequence:

MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG 
QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL 
PSRTVDTKQA QELARSYGIP FIETSAKTRQ RVEDAFYTLV REIRQYRLKK ISKEEKTPGC 
VKIKKCVIM

Genular Protein ID: 462577752

Symbol: Q5J7N1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q5J7N1

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 188
Mass: 21483
Checksum: B0A542E8AD158F51
Sequence:

MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG 
QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL 
PSRTVDTKQA QELARSYGIP FIETSAKTRQ GVDDAFYTLV REIRKHKEKM SKDGKKKKKK 
SRTRCTVM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Kras

Associated with

Other Information

Structure and expression of amplified cKi-ras gene sequences in Y1 mouse adrenal tumor cells. PubMed ID: 4006913

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Activation of a c-K-ras oncogene by somatic mutation in mouse lymphomas induced by gamma radiation. PubMed ID: 6474169

Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids. PubMed ID: 1352876

Amplified DNA in Y1 mouse adrenal tumor cells: isolation of cDNAs complementary to an amplified c-Ki-ras gene and localization of homologous sequences to mouse chromosome 6. PubMed ID: 6546797

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Database document:

PubMed ID: 4006913

PubMed ID: 15489334

PubMed ID: 6474169

PubMed ID: 1352876

PubMed ID: 6546797

PubMed ID: 21183079

PubMed ID: 10349636

PubMed ID: 11042159

PubMed ID: 11076861

PubMed ID: 11217851

PubMed ID: 12466851

PubMed ID: 15489334

PubMed ID: 16141073