Krt14 | ENSMUSG00000045545 | NCBI 16664

Details for: Krt14

Gene ID: 16664

Symbol: Krt14

Ensembl ID: ENSMUSG00000045545

Description: keratin 14

Associated with

Cell-cell communication
(R-MMU-1500931)
Cell junction organization
(R-MMU-446728)
Developmental biology
(R-MMU-1266738)
Formation of the cornified envelope
(R-MMU-6809371)
Keratinization
(R-MMU-6805567)
Type i hemidesmosome assembly
(R-MMU-446107)
Basal part of cell
(GO:0045178)
Cell periphery
(GO:0071944)
Cornified envelope
(GO:0001533)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Epithelial cell differentiation
(GO:0030855)
Hair cycle
(GO:0042633)
Intermediate filament
(GO:0005882)
Intermediate filament bundle assembly
(GO:0045110)
Intermediate filament organization
(GO:0045109)
Intracellular anatomical structure
(GO:0005622)
Keratin filament
(GO:0045095)
Keratin filament binding
(GO:1990254)
Keratinocyte differentiation
(GO:0030216)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Stem cell differentiation
(GO:0048863)
Structural molecule activity
(GO:0005198)

Other Information

Proteins

Keratin, type I cytoskeletal 14

Genular Protein ID: 3688602912

Symbol: K1C14_MOUSE

Name: Keratin, type I cytoskeletal 14

UniProtKB Accession Codes:

Q61781 A2A4G4 Q91VQ4 Q99LE0

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22705788

Title: Structural basis for heteromeric assembly and perinuclear organization of keratin filaments.

PubMed ID: 22705788

DOI: 10.1038/nsmb.2330

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2433272

Title: Three cDNA sequences of mouse type I keratins: cellular localization of the mRNAs in normal and hyperproliferative tissues.

PubMed ID: 2433272

DOI: 10.1016/s0021-9258(19)75876-1

PubMed ID: 11408584

Title: Complete cytolysis and neonatal lethality in keratin 5 knockout mice reveal its fundamental role in skin integrity and in epidermolysis bullosa simplex.

PubMed ID: 11408584

DOI: 10.1091/mbc.12.6.1775

PubMed ID: 12657653

Title: Amelogenin interacts with cytokeratin-5 in ameloblasts during enamel growth.

PubMed ID: 12657653

DOI: 10.1074/jbc.m211184200

PubMed ID: 16702408

Title: Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion.

PubMed ID: 16702408

DOI: 10.1101/gad.1387406

PubMed ID: 18285451

Title: Stress-induced recruitment of epiplakin to keratin networks increases their resistance to hyperphosphorylation-induced disruption.

PubMed ID: 18285451

DOI: 10.1242/jcs.013755

PubMed ID: 19267394

Title: Cytokines as genetic modifiers in K5-/- mice and in human epidermolysis bullosa simplex.

PubMed ID: 19267394

DOI: 10.1002/humu.20981

PubMed ID: 24940650

Title: Interaction of plectin with keratins 5 and 14: dependence on several plectin domains and keratin quaternary structure.

PubMed ID: 24940650

DOI: 10.1038/jid.2014.255

PubMed ID: 26758872

Title: Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy.

PubMed ID: 26758872

DOI: 10.1093/hmg/ddw001

Sequence Information:

Length: 484
Mass: 52867
Checksum: A9B6BA66B2F46668
Sequence:

MATCSRQFTS SSSMKGSCGI GGGSSRMSSI LAGGSCRAPS TYGGMSVTSS RFSSGGACGI 
GGGYGGSFSS SSFGGGLGSG FGGRFDGFGG GFGGGLGGGF GGGLGGGLGG GIGDGLLVGS 
EKVTMQNLND RLATYLDKVR ALEEANTELE VKIRDWYQRQ RPTEIKDYSP YFKTIEDLKS 
KILAATVDNA NVLLQIDNAR LAADDFRTKF ETEQSLRMSV EADINGLRRV LDELTLARAD 
LEMQIESLKE ELAYLKKNHE EEMASMRGQV GGDVNVEMDA APGVDLSRIL NEMRDQYEKM 
AEKNRKDAEE WFFSKTEELN REVATNSELV QSGKSEISEL RRTMQNLEIE LQSQLSMKAS 
LENNLEETKG RYCMQLAQIQ EMIGSVEEQL AQLRCEMEQQ NQEYKILLDV KTRLEQEIAT 
YRRLLEGEDA HLSSSQFSSS SQFSSGSQSS RDVTSTNRQI RTKVMDVHDG KVVSTHEQVL 
RTKN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Krt14

Associated with

Other Information

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Structural basis for heteromeric assembly and perinuclear organization of keratin filaments. PubMed ID: 22705788

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Three cDNA sequences of mouse type I keratins: cellular localization of the mRNAs in normal and hyperproliferative tissues. PubMed ID: 2433272

Complete cytolysis and neonatal lethality in keratin 5 knockout mice reveal its fundamental role in skin integrity and in epidermolysis bullosa simplex. PubMed ID: 11408584

Amelogenin interacts with cytokeratin-5 in ameloblasts during enamel growth. PubMed ID: 12657653

Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion. PubMed ID: 16702408

Stress-induced recruitment of epiplakin to keratin networks increases their resistance to hyperphosphorylation-induced disruption. PubMed ID: 18285451

Cytokines as genetic modifiers in K5-/- mice and in human epidermolysis bullosa simplex. PubMed ID: 19267394

Interaction of plectin with keratins 5 and 14: dependence on several plectin domains and keratin quaternary structure. PubMed ID: 24940650

Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy. PubMed ID: 26758872