Details for: Krt2

Gene ID: 16681

Symbol: Krt2

Ensembl ID: ENSMUSG00000064201

Description: keratin 2

Associated with

Other Information

Genular Protein ID: 1269378663

Symbol: K22E_MOUSE

Name: Keratin, type II cytoskeletal 2 epidermal

UniProtKB Accession Codes:

Q3TTY5 Q0VBW1 Q61869

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CPTAC 1 CTD 1 DNASU 1 EMBL 9 Ensembl 1 GO 13 Gene3D 3 GeneTree 1 Genevisible 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 2448177

Title: An unusual type-II 70-kilodalton keratin protein of mouse epidermis exhibiting postnatal body-site specificity and sensitivity to hyperproliferation.

PubMed ID: 2448177

DOI: 10.1111/j.1432-0436.1987.tb00066.x

PubMed ID: 7508961

Title: The large type II 70-kDa keratin of mouse epidermis is the ortholog of human keratin K2e.

PubMed ID: 7508961

DOI: 10.1111/1523-1747.ep12371757

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9378767

Title: Out of balance: consequences of a partial keratin 10 knockout.

PubMed ID: 9378767

DOI: 10.1242/jcs.110.18.2175

PubMed ID: 15118396

Title: Keratin 2e: a marker for murine nipple epidermis.

PubMed ID: 15118396

DOI: 10.1159/000077033

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24751727

Title: Loss of keratin K2 expression causes aberrant aggregation of K10, hyperkeratosis, and inflammation.

PubMed ID: 24751727

DOI: 10.1038/jid.2014.197

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 26603179

Title: Keratins K2 and K10 are essential for the epidermal integrity of plantar skin.

PubMed ID: 26603179

DOI: 10.1016/j.jdermsci.2015.10.008

PubMed ID: 12533510

Title: Genetics of dark skin in mice.

PubMed ID: 12533510

DOI: 10.1101/gad.1023703

Sequence Information:

  • Length: 707
  • Mass: 70923
  • Checksum: 464D375DCBA90EF4
  • Sequence:
    • MSCQISCRSR RGGGGGGGGG FRGFSSGSAV VSGGSRRSNT SFSCISRHGG GRGGSGGGGF 
GSQSLVGLGG YKSISSSVAG NSGGYGGSSF GGSSGFGGGR GFGGGQGFGG SGGFGGGSGF 
GGGQGFGGGS RFGGGSGFGG GGFGGGSFGG GRFGGGPGGF GGPGGFPGGG IHEVSVNQSL 
LQPLDVKVDP EIQNVKSQER EQIKTLNNKF ASFIDKVRFL EQQNQVLRTK WELLQQLDVG 
SRTTNLDPIF QAYIGMLKKQ VDRLSAERTS QESELNNMQD LVEDFKKKYE DEINKRTSAE 
NDFVTIKKDV DSCYMDKTEL QARLDILAQE VNFLRTLYDA ELSQLQQDVT DTNVILSMDN 
NRNLDLDSII AEVQNQYEMI AHKSKAESEE LYHSKYEELQ VTAVKHGDSL KEIKMEISEL 
NRTIQRLQGE ISHVKKQCKG VQDSIADAEQ RGEHAIKDAR GKLTDLEEAL QQCREDLARL 
LRDYQELMNT KLSLDVEIAT YRKLLEGEEC RMSGDFSDNV SVSITSSTIS SSVASKTGFG 
SGGQSSGGRG SYGGRGGGGG GGSTYGSGGR SSGSRGSGSG SGGGGYSSGG GSRGGSGGGY 
GSGGGSRGGS GGGYGSGGGS GSGGGYSSGG GSRGGSGGGG VSSGGGSRGG SSSGGGSRGG 
SSSGGGGYSS GGGSRGGSSS GGAGSSSEKG GSGSGEGCGS GVTFSFR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.