Details for: Lag3
Associated with
Other Information
Genular Protein ID: 4195979777
Symbol: LAG3_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8921170
Title: Cloning of murine LAG-3 by magnetic bead bound homologous probes and PCR (gene-capture PCR).
PubMed ID: 8921170
PubMed ID: 8602528
Title: Independent modes of natural killing distinguished in mice lacking Lag3.
PubMed ID: 8602528
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12209638
Title: Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3).
PubMed ID: 12209638
DOI: 10.1002/1521-4141(200208)32:8<2255::aid-immu2255>3.0.co;2-a
PubMed ID: 11937541
Title: Maturation and activation of dendritic cells induced by lymphocyte activation gene-3 (CD223).
PubMed ID: 11937541
PubMed ID: 12421911
Title: Molecular analysis of the negative regulatory function of lymphocyte activation gene-3.
PubMed ID: 12421911
PubMed ID: 12672063
Title: The CD4-related molecule, LAG-3 (CD223), regulates the expansion of activated T cells.
PubMed ID: 12672063
PubMed ID: 15485628
PubMed ID: 15100286
Title: Lymphocyte activation gene-3 (CD223) regulates the size of the expanding T cell population following antigen activation in vivo.
PubMed ID: 15100286
PubMed ID: 15557174
Title: Biochemical analysis of the regulatory T cell protein lymphocyte activation gene-3 (LAG-3; CD223).
PubMed ID: 15557174
PubMed ID: 15634887
Title: Negative regulation of T cell homeostasis by lymphocyte activation gene-3 (CD223).
PubMed ID: 15634887
PubMed ID: 17245433
Title: Metalloproteases regulate T-cell proliferation and effector function via LAG-3.
PubMed ID: 17245433
PubMed ID: 19201841
Title: LAG-3 regulates plasmacytoid dendritic cell homeostasis.
PubMed ID: 19201841
PubMed ID: 21300912
Title: PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice.
PubMed ID: 21300912
DOI: 10.1084/jem.20100466
PubMed ID: 21873518
Title: Accelerated autoimmune diabetes in the absence of LAG-3.
PubMed ID: 21873518
PubMed ID: 30580966
Title: Fibrinogen-like protein 1 is a major immune inhibitory ligand of LAG-3.
PubMed ID: 30580966
PubMed ID: 30349037
Title: LAG-3 inhibits the activation of CD4+ T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII.
PubMed ID: 30349037
Sequence Information:
- Length: 521
- Mass: 56978
- Checksum: 64C29C40EB780E48
- Sequence:
MREDLLLGFL LLGLLWEAPV VSSGPGKELP VVWAQEGAPV HLPCSLKSPN LDPNFLRRGG VIWQHQPDSG QPTPIPALDL HQGMPSPRQP APGRYTVLSV APGGLRSGRQ PLHPHVQLEE RGLQRGDFSL WLRPALRTDA GEYHATVRLP NRALSCSLRL RVGQASMIAS PSGVLKLSDW VLLNCSFSRP DRPVSVHWFQ GQNRVPVYNS PRHFLAETFL LLPQVSPLDS GTWGCVLTYR DGFNVSITYN LKVLGLEPVA PLTVYAAEGS RVELPCHLPP GVGTPSLLIA KWTPPGGGPE LPVAGKSGNF TLHLEAVGLA QAGTYTCSIH LQGQQLNATV TLAVITVTPK SFGLPGSRGK LLCEVTPASG KERFVWRPLN NLSRSCPGPV LEIQEARLLA ERWQCQLYEG QRLLGATVYA AESSSGAHSA RRISGDLKGG HLVLVLILGA LSLFLLVAGA FGFHWWRKQL LLRRFSALEH GIQPFPAQRK IEELERELET EMGQEPEPEP EPQLEPEPRQ L
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.