Genular: Defining Cellular Identity and Function

Details for: Rpsa

Gene ID: 16785

Symbol: Rpsa

Ensembl ID: ENSMUSG00000032518

Description: ribosomal protein SA

Associated with

Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
(R-MMU-72662)
Cap-dependent translation initiation
(R-MMU-72737)
Eukaryotic translation initiation
(R-MMU-72613)
Formation of a pool of free 40s subunits
(R-MMU-72689)
Formation of the ternary complex, and subsequently, the 43s complex
(R-MMU-72695)
Gtp hydrolysis and joining of the 60s ribosomal subunit
(R-MMU-72706)
L13a-mediated translational silencing of ceruloplasmin expression
(R-MMU-156827)
Major pathway of rrna processing in the nucleolus and cytosol
(R-MMU-6791226)
Metabolism of proteins
(R-MMU-392499)
Metabolism of rna
(R-MMU-8953854)
Nonsense-mediated decay (nmd)
(R-MMU-927802)
Nonsense mediated decay (nmd) enhanced by the exon junction complex (ejc)
(R-MMU-975957)
Nonsense mediated decay (nmd) independent of the exon junction complex (ejc)
(R-MMU-975956)
Ribosomal scanning and start codon recognition
(R-MMU-72702)
Rrna processing
(R-MMU-72312)
Rrna processing in the nucleus and cytosol
(R-MMU-8868773)
Srp-dependent cotranslational protein targeting to membrane
(R-MMU-1799339)
Translation initiation complex formation
(R-MMU-72649)
Basement membrane
(GO:0005604)
Cell-cell adhesion
(GO:0098609)
Collagen-containing extracellular matrix
(GO:0062023)
Cytoplasm
(GO:0005737)
Cytoplasmic translation
(GO:0002181)
Cytosol
(GO:0005829)
Cytosolic ribosome
(GO:0022626)
Cytosolic small ribosomal subunit
(GO:0022627)
Glutamatergic synapse
(GO:0098978)
Laminin binding
(GO:0043236)
Laminin receptor activity
(GO:0005055)
Membrane
(GO:0016020)
Neuronal cell body
(GO:0043025)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Postsynapse
(GO:0098794)
Protein binding
(GO:0005515)
Ribonucleoprotein complex
(GO:1990904)
Ribosomal small subunit assembly
(GO:0000028)
Ribosome
(GO:0005840)
Ribosome binding
(GO:0043022)
Small ribosomal subunit
(GO:0015935)
Structural constituent of ribosome
(GO:0003735)
Synapse
(GO:0045202)
Translation
(GO:0006412)

Other Information

Proteins

37 kDa oncofetal antigen

Genular Protein ID: 4102359435

Symbol: RSSA_MOUSE

Name: 37 kDa oncofetal antigen

UniProtKB Accession Codes:

P14206 Q58E74 Q8BHL0 Q8BNL2 Q91V31 Q9CY13

Database IDs:

Citations:

PubMed ID: 2531008

Title: Evidence for a precursor of the high-affinity metastasis-associated murine laminin receptor.

PubMed ID: 2531008

DOI: 10.1021/bi00444a047

PubMed ID: 3357791

Title: Nucleotide sequence for a major messenger RNA for a 40 kilodalton polypeptide that is under translational control in mouse tumor cells.

PubMed ID: 3357791

DOI: 10.1093/nar/16.5.2349

PubMed ID: 10697612

Title: 37 kilodalton oncofetal antigen protein and immature laminin receptor protein are identical, universal T-cell inducing immunogens on primary rodent and human cancers.

PubMed ID: 10697612

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8954992

Title: Analysis of nuclear localization of laminin binding protein precursor p40 (LBP/p40).

PubMed ID: 8954992

DOI: 10.1006/bbrc.1996.1899

PubMed ID: 6301485

Title: Isolation of a tumor cell laminin receptor.

PubMed ID: 6301485

DOI: 10.1016/0006-291x(83)91370-0

PubMed ID: 16453457

Title: Isolation of a laminin-binding protein from muscle cell membranes.

PubMed ID: 16453457

DOI: 10.1002/j.1460-2075.1983.tb01514.x

PubMed ID: 6302102

Title: Isolation of a cell surface receptor protein for laminin from murine fibrosarcoma cells.

PubMed ID: 6302102

DOI: 10.1083/jcb.96.5.1475

PubMed ID: 1374897

Title: A 33-kDa polypeptide with homology to the laminin receptor: component of translation machinery.

PubMed ID: 1374897

DOI: 10.1073/pnas.89.10.4368

PubMed ID: 11689427

Title: The 37-kDa/67-kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein.

PubMed ID: 11689427

DOI: 10.1093/emboj/20.21.5863

PubMed ID: 11597123

Title: Midkine binds to 37-kDa laminin binding protein precursor, leading to nuclear transport of the complex.

PubMed ID: 11597123

DOI: 10.1006/excr.2001.5341

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 18339329

Title: Subcellular localization of prion proteins and the 37 kDa/67 kDa laminin receptor fused to fluorescent proteins.

PubMed ID: 18339329

DOI: 10.1016/j.bbadis.2008.02.003

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 36517592

Title: A male germ-cell-specific ribosome controls male fertility.

PubMed ID: 36517592

DOI: 10.1038/s41586-022-05508-0

Sequence Information:

Length: 295
Mass: 32838
Checksum: C698CFA6B759FD2E
Sequence:

MSGALDVLQM KEEDVLKFLA AGTHLGGTNL DFQMEQYIYK RKSDGIYIIN LKRTWEKLLL 
AARAIVAIEN PADVSVISSR NTGQRAVLKF AAATGATPIA GRFTPGTFTN QIQAAFREPR 
LLVVTDPRAD HQPLTEASYV NLPTIALCNT DSPLRYVDIA IPCNNKGAHS VGLMWWMLAR 
EVLRMRGTIS REHPWEVMPD LYFYRDPEEI EKEEQAAAEK AVTKEEFQGE WTAPAPEFTA 
AQPEVADWSE GVQVPSVPIQ QFPTEDWSAQ PATEDWSAAP TAQATEWVGA TTEWS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rpsa

Associated with

Other Information

Evidence for a precursor of the high-affinity metastasis-associated murine laminin receptor. PubMed ID: 2531008

Nucleotide sequence for a major messenger RNA for a 40 kilodalton polypeptide that is under translational control in mouse tumor cells. PubMed ID: 3357791

37 kilodalton oncofetal antigen protein and immature laminin receptor protein are identical, universal T-cell inducing immunogens on primary rodent and human cancers. PubMed ID: 10697612

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Analysis of nuclear localization of laminin binding protein precursor p40 (LBP/p40). PubMed ID: 8954992

Isolation of a tumor cell laminin receptor. PubMed ID: 6301485

Isolation of a laminin-binding protein from muscle cell membranes. PubMed ID: 16453457

Isolation of a cell surface receptor protein for laminin from murine fibrosarcoma cells. PubMed ID: 6302102

A 33-kDa polypeptide with homology to the laminin receptor: component of translation machinery. PubMed ID: 1374897

The 37-kDa/67-kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein. PubMed ID: 11689427

Midkine binds to 37-kDa laminin binding protein precursor, leading to nuclear transport of the complex. PubMed ID: 11597123

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. PubMed ID: 15592455

Subcellular localization of prion proteins and the 37 kDa/67 kDa laminin receptor fused to fluorescent proteins. PubMed ID: 18339329

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

A male germ-cell-specific ribosome controls male fertility. PubMed ID: 36517592