Details for: Lck
Associated with
Other Information
Genular Protein ID: 2653073185
Symbol: LCK_MOUSE
Name: Proto-oncogene tyrosine-protein kinase LCK
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2416464
Title: A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA.
PubMed ID: 2416464
PubMed ID: 3081813
Title: Expression of a new tyrosine protein kinase is stimulated by retrovirus promoter insertion.
PubMed ID: 3081813
DOI: 10.1038/319682a0
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2850479
Title: Structure of the murine lck gene and its rearrangement in a murine lymphoma cell line.
PubMed ID: 2850479
PubMed ID: 3501824
Title: Two lck transcripts containing different 5' untranslated regions are present in T cells.
PubMed ID: 3501824
PubMed ID: 3380790
Title: Avian reovirus mRNAs are nonfunctional in infected mouse cells: translational basis for virus host-range restriction.
PubMed ID: 3380790
PubMed ID: 2107025
Title: Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs.
PubMed ID: 2107025
PubMed ID: 1279202
Title: Creation and characterization of temperature-sensitive mutants of the lck tyrosine protein kinase.
PubMed ID: 1279202
PubMed ID: 1706070
Title: Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck.
PubMed ID: 1706070
DOI: 10.1038/350062a0
PubMed ID: 1708890
Title: Thymic tumorigenesis induced by overexpression of p56lck.
PubMed ID: 1708890
PubMed ID: 1579166
Title: Profound block in thymocyte development in mice lacking p56lck.
PubMed ID: 1579166
DOI: 10.1038/357161a0
PubMed ID: 8371758
Title: Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk.
PubMed ID: 8371758
DOI: 10.1038/365156a0
PubMed ID: 8421674
Title: The conserved lysine of the catalytic domain of protein kinases is actively involved in the phosphotransfer reaction and not required for anchoring ATP.
PubMed ID: 8421674
PubMed ID: 8413237
Title: Palmitylation of an amino-terminal cysteine motif of protein tyrosine kinases p56lck and p59fyn mediates interaction with glycosyl-phosphatidylinositol-anchored proteins.
PubMed ID: 8413237
PubMed ID: 7980442
Title: Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif.
PubMed ID: 7980442
DOI: 10.1042/bj3030749
PubMed ID: 10646608
Title: Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b.
PubMed ID: 10646608
DOI: 10.1038/35003228
PubMed ID: 12218089
Title: Fyn is essential for tyrosine phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells.
PubMed ID: 12218089
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
Sequence Information:
- Length: 509
- Mass: 57943
- Checksum: 3513102F49A7FD0B
- Sequence:
MGCVCSSNPE DDWMENIDVC ENCHYPIVPL DSKISLPIRN GSEVRDPLVT YEGSLPPASP LQDNLVIALH SYEPSHDGDL GFEKGEQLRI LEQSGEWWKA QSLTTGQEGF IPFNFVAKAN SLEPEPWFFK NLSRKDAERQ LLAPGNTHGS FLIRESESTA GSFSLSVRDF DQNQGEVVKH YKIRNLDNGG FYISPRITFP GLHDLVRHYT NASDGLCTKL SRPCQTQKPQ KPWWEDEWEV PRETLKLVER LGAGQFGEVW MGYYNGHTKV AVKSLKQGSM SPDAFLAEAN LMKQLQHPRL VRLYAVVTQE PIYIITEYME NGSLVDFLKT PSGIKLNVNK LLDMAAQIAE GMAFIEEQNY IHRDLRAANI LVSDTLSCKI ADFGLARLIE DNEYTAREGA KFPIKWTAPE AINYGTFTIK SDVWSFGILL TEIVTHGRIP YPGMTNPEVI QNLERGYRMV RPDNCPEELY HLMMLCWKER PEDRPTFDYL RSVLDDFFTA TEGQYQPQP
Genular Protein ID: 3595741417
Symbol: E9Q696_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
Sequence Information:
- Length: 520
- Mass: 59003
- Checksum: 76DC69BEF5907FCC
- Sequence:
MGASELTISG IMGCVCSSNP EDDWMENIDV CENCHYPIVP LDSKISLPIR NGSEVRDPLV TYEGSLPPAS PLQDNLVIAL HSYEPSHDGD LGFEKGEQLR ILEQSGEWWK AQSLTTGQEG FIPFNFVAKA NSLEPEPWFF KNLSRKDAER QLLAPGNTHG SFLIRESEST AGSFSLSVRD FDQNQGEVVK HYKIRNLDNG GFYISPRITF PGLHDLVRHY TNASDGLCTK LSRPCQTQKP QKPWWEDEWE VPRETLKLVE RLGAGQFGEV WMGYYNGHTK VAVKSLKQGS MSPDAFLAEA NLMKQLQHPR LVRLYAVVTQ EPIYIITEYM ENGSLVDFLK TPSGIKLNVN KLLDMAAQIA EGMAFIEEQN YIHRDLRAAN ILVSDTLSCK IADFGLARLI EDNEYTAREG AKFPIKWTAP EAINYGTFTI KSDVWSFGIL LTEIVTHGRI PYPGMTNPEV IQNLERGYRM VRPDNCPEEL YHLMMLCWKE RPEDRPTFDY LRSVLDDFFT ATEGQYQPQP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.