Details for: Lef1

Gene ID: 16842

Symbol: Lef1

Ensembl ID: ENSMUSG00000027985

Description: lymphoid enhancer binding factor 1

Associated with

Other Information

Genular Protein ID: 3206040154

Symbol: LEF1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1827423

Title: LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function.

PubMed ID: 1827423

DOI: 10.1101/gad.5.5.880

PubMed ID: 8415007

Title: Nucleotide sequence of a cDNA encoding an alternative form of LEF-1.

PubMed ID: 8415007

DOI: 10.1093/nar/21.18.4403

PubMed ID: 8898217

Title: Msx1 controls inductive signaling in mammalian tooth morphogenesis.

PubMed ID: 8898217

DOI: 10.1242/dev.122.10.3035

PubMed ID: 10498690

Title: Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation.

PubMed ID: 10498690

DOI: 10.1242/dev.126.20.4557

PubMed ID: 10966653

Title: Hot spots in beta-catenin for interactions with LEF-1, conductin and APC.

PubMed ID: 10966653

DOI: 10.1038/79039

PubMed ID: 11445543

Title: Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin.

PubMed ID: 11445543

DOI: 10.1101/gad.891401

PubMed ID: 11731474

Title: PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies.

PubMed ID: 11731474

DOI: 10.1101/gad.944801

PubMed ID: 12446687

Title: Identification of a promoter-specific transcriptional activation domain at the C-terminus of the Wnt effector protein T-cell factor 4.

PubMed ID: 12446687

DOI: 10.1074/jbc.m210081200

PubMed ID: 17218525

Title: Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13.

PubMed ID: 17218525

DOI: 10.1126/science.1135344

PubMed ID: 19304756

Title: Dazap2 modulates transcription driven by the Wnt effector TCF-4.

PubMed ID: 19304756

DOI: 10.1093/nar/gkp179

PubMed ID: 23562159

Title: A network of high-mobility group box transcription factors programs innate interleukin-17 production.

PubMed ID: 23562159

DOI: 10.1016/j.immuni.2013.01.010

PubMed ID: 27713059

Title: Bmp4-Msx1 signaling and Osr2 control tooth organogenesis through antagonistic regulation of secreted Wnt antagonists.

PubMed ID: 27713059

DOI: 10.1016/j.ydbio.2016.10.001

PubMed ID: 29148101

Title: Homeobox protein MSX-1 inhibits expression of bone morphogenetic protein 2, bone morphogenetic protein 4, and lymphoid enhancer-binding factor 1 via Wnt/beta-catenin signaling to prevent differentiation of dental mesenchymal cells during the late bell stage.

PubMed ID: 29148101

DOI: 10.1111/eos.12390

PubMed ID: 7651541

Title: Structural basis for DNA bending by the architectural transcription factor LEF-1.

PubMed ID: 7651541

DOI: 10.1038/376791a0

Sequence Information:

  • Length: 397
  • Mass: 44059
  • Checksum: 0CA01B6C528FD7FA
  • Sequence:
  • MPQLSGGGGG GDPELCATDE MIPFKDEGDP QKEKIFAEIS HPEEEGDLAD IKSSLVNESE 
    IIPASNGHEV VRQAPSSQEP YHDKAREHPD EGKHPDGGLY NKGPSYSSYS GYIMMPNMNS 
    DPYMSNGSLS PPIPRTSNKV PVVQPSHAVH PLTPLITYSD EHFSPGSHPS HIPSDVNSKQ 
    GMSRHPPAPE IPTFYPLSPG GVGQITPPIG WQGQPVYPIT GGFRQPYPSS LSGDTSMSRF 
    SHHMIPGPPG PHTTGIPHPA IVTPQVKQEH PHTDSDLMHV KPQHEQRKEQ EPKRPHIKKP 
    LNAFMLYMKE MRANVVAECT LKESAAINQI LGRRWHALSR EEQAKYYELA RKERQLHMQL 
    YPGWSARDNY GKKKKRKREK LQESTSGTGP RMTAAYI

Genular Protein ID: 1188632615

Symbol: Q8C402_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 331
  • Mass: 37041
  • Checksum: 383E0F6AA6F7E84F
  • Sequence:
  • MAGVVRQAPS SQEPYHDKAR EHPDEGKHPD GGLYNKGPSY SSYSGYIMMP NMNSDPYMSN 
    GSLSPPIPRT SNKVPVVQPS HAVHPLTPLI TYSDEHFSPG SHPSHIPSDV NSKQGMSRHP 
    PAPEIPTFYP LSPGGVGQIT PPIGWQGQPV YPITGGFRQP YPSSLSGDTS MSRFSHHMIP 
    GPPGPHTTGI PHPAIVTPQV KQEHPHTDSD LMHVKPQHEQ RKEQEPKRPH IKKPLNAFML 
    YMKEMRANVV AECTLKESAA INQILGRRWH ALSREEQAKY YELARKERQL HMQLYPGWSA 
    RDNYGKKKKR KREKLQESTS GTGPRMTAAY I

Genular Protein ID: 2386117805

Symbol: Q8BGZ9_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 384
  • Mass: 42576
  • Checksum: 5E9313F72287ECCE
  • Sequence:
  • MPQLSGGGGG GDPELCATDE MIPFKDEGDP QKEKIFAEIS HPEEEGDLAD IKSSLVNESE 
    IIPASNGHEV VRQAPSSQEP YHDKAREHPD EGKHPDGGLY NKGPSYSSYS GYIMMPNMNS 
    DPYMSNGSLS PPIPRTSNKV PVVQPSHAVH PLTPLITYSD EHFSPGSHPS HIPSDVNSKQ 
    GMSRHPPAPE IPTFYPLSPG GVGQITPPIG WFSHHMIPGP PGPHTTGIPH PAIVTPQVKQ 
    EHPHTDSDLM HVKPQHEQRK EQEPKRPHIK KPLNAFMLYM KEMRANVVAE CTLKESAAIN 
    QILGRRWHAL SREEQAKYYE LARKERQLHM QLYPGWSARD NYGKKKKRKR EKLQESTSGG 
    KRSSFPTCKA KAATPGPLLE MEAC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.