Details for: Lfng

Gene ID: 16848

Symbol: Lfng

Ensembl ID: ENSMUSG00000029570

Description: LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Associated with

Other Information

Genular Protein ID: 4054406228

Symbol: LFNG_MOUSE

Name: O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

UniProtKB Accession Codes:

O09010 Q3U659 Q8K3F1 Q9DC10

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID-ORCS 1 CAZy 1 CCDS 1 CTD 1 ChEBI 14 DNASU 1 EC 2 EMBL 5 Ensembl 1 ExpressionAtlas 1 GO 13 Gene3D 1 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 2 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 Rhea 6 SAM 1 SMR 1 STRING 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 9187150

Title: A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

PubMed ID: 9187150

DOI: 10.1242/dev.124.11.2245

PubMed ID: 9207795

Title: Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila.

PubMed ID: 9207795

DOI: 10.1038/ng0797-283

PubMed ID: 12110169

Title: Clock regulatory elements control cyclic expression of Lunatic fringe during somitogenesis.

PubMed ID: 12110169

DOI: 10.1016/s1534-5807(02)00212-5

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 10330372

Title: Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse.

PubMed ID: 10330372

DOI: 10.1016/s0960-9822(99)80212-7

PubMed ID: 10935626

Title: Fringe is a glycosyltransferase that modifies Notch.

PubMed ID: 10935626

DOI: 10.1038/35019000

PubMed ID: 12167404

Title: Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth.

PubMed ID: 12167404

DOI: 10.1006/dbio.2002.0734

PubMed ID: 9690473

Title: Lunatic fringe is an essential mediator of somite segmentation and patterning.

PubMed ID: 9690473

DOI: 10.1038/28632

PubMed ID: 10341080

Title: Genomic structure, mapping, and expression analysis of the mammalian Lunatic, Manic, and Radical fringe genes.

PubMed ID: 10341080

DOI: 10.1007/s003359901039

PubMed ID: 11520458

Title: Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1.

PubMed ID: 11520458

DOI: 10.1016/s1074-7613(01)00189-3

PubMed ID: 12110168

Title: Periodic Lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to notch signaling.

PubMed ID: 12110168

DOI: 10.1016/s1534-5807(02)00211-3

PubMed ID: 16221665

Title: Lunatic fringe, manic fringe, and radical fringe recognize similar specificity determinants in O-fucosylated epidermal growth factor-like repeats.

PubMed ID: 16221665

DOI: 10.1074/jbc.m509552200

PubMed ID: 16385447

Title: Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype.

PubMed ID: 16385447

DOI: 10.1086/498879

PubMed ID: 28089369

Title: Deciphering the fringe-mediated notch code: identification of activating and inhibiting sites allowing discrimination between ligands.

PubMed ID: 28089369

DOI: 10.1016/j.devcel.2016.12.013

Sequence Information:

  • Length: 378
  • Mass: 41952
  • Checksum: FD0A02597BF9AFED
  • Sequence:
    • MLQRCGRRLL LALVGALLAC LLVLTADPPP TPMPAERGRR ALRSLAGSSG GAPASGSRAA 
VDPGVLTREV HSLSEYFSLL TRARRDADPP PGVASRQGDG HPRPPAEVLS PRDVFIAVKT 
TRKFHRARLD LLFETWISRH KEMTFIFTDG EDEALAKLTG NVVLTNCSSA HSRQALSCKM 
AVEYDRFIES GKKWFCHVDD DNYVNLRALL RLLASYPHTQ DVYIGKPSLD RPIQATERIS 
EHKVRPVHFW FATGGAGFCI SRGLALKMGP WASGGHFMST AERIRLPDDC TIGYIVEALL 
GVPLIRSGLF HSHLENLQQV PTTELHEQVT LSYGMFENKR NAVHIKGPFS VEADPSRFRS 
VHCHLYPDTP WCPRSAIF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.